A Case Report of Living Donor Liver Transplantation for Fulminant Hepatitis Related to Hepatitis E Virus Infection

2017 ◽  
Vol 28 (1) ◽  
pp. 91-92
Author(s):  
Keita Shimata ◽  
Yasuhiko Sugawara ◽  
Hidekazu Yamamoto ◽  
Hiroaki Okamoto ◽  
Koushi Uchida ◽  
...  

Hepatitis E virus (HEV) infection which may become fulminant, especially in elderly people is more common than previously recognized in develop countries. Here we report successful living-donor liver transplantation (LDLT) in a case of acute liver failure due to HEV. A 63-year-old Japanese man with no previous history of liver disease was admitted for severe acute hepatitis. Detection of anti-HEV immunoglobulin A established a diagnosis of this virus-related liver failure. The patient suffered from hepatic encephalopathy 10 days after symptom onset and underwent LDLT. The patient had an uneventful course. The HEV RNA showed spontaneous negative conversion 10 weeks after LDLT. LDLT led to a successful outcome in a patient with acute liver failure due to HEV infection and regular testing for HEV RNA should be performed until HEV RNA is undetectable.

2009 ◽  
Vol 136 (5) ◽  
pp. A-416
Author(s):  
Anantha Narayanan ◽  
Supriya Sharma ◽  
Gaurav Pande ◽  
Ismail Siyad ◽  
Geeta Sanil ◽  
...  

PLoS ONE ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. e0193327 ◽  
Author(s):  
Marek Szymczak ◽  
Piotr Kaliciński ◽  
Grzegorz Kowalewski ◽  
Dorota Broniszczak ◽  
Małgorzata Markiewicz-Kijewska ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
Naoya Kanogawa ◽  
Tatsuo Kanda ◽  
Masayuki Ohtsuka ◽  
Masato Nakamura ◽  
Tatsuo Miyamura ◽  
...  

Acute liver failure (ALF) during pregnancy remains difficult to treat, and despite advances in treatment, liver transplantation must be selected as treatment option in certain cases. We report a 30-year-old woman with ALF of unknown etiology, occurring during the first trimester of pregnancy. Her condition was complicated by consciousness disturbance and coagulopathy due to ALF, but she was successfully treated with living donor liver transplantation 7 days after dilatation and curettage. At 9-month followup, she was in good medical condition. Liver transplantation has been reported as one of the treatment options for ALF during pregnancy with the prognosis varying depending on the trimester, from living donor or deceased donor liver transplantation. Of importance is that clinicians always think of emergent liver transplantation as a therapeutic option in ALF even in the first trimester of pregnancy.


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