scholarly journals Antioxidant Effects on Lipid Peroxidation by Superoxide of Echinoisoflavanone and Sophoraisoflavanone D from Sophora Chrysophylla Seem

2006 ◽  
Vol 1 (7) ◽  
pp. 1934578X0600100
Author(s):  
Shizuo Toda ◽  
Yoshiaki Shirataki
Keyword(s):  
Lipid Peroxidation ◽  
Xanthine Oxidase ◽  
Superoxide Anion ◽  
Antioxidant Property ◽  
Antioxidant Effect ◽  
Oxidase System ◽  
Antioxidant Effects

The possible antioxidant effect of two isoflavanones, echinoisoflavanone and sophoraisoflavanone D from Sophora chrysophylla Seem. was investigated. Both these compounds inhibited the superoxide anion-mediated lipid peroxidation of lecithin and scavenged superoxide anion generated by the xanthine-xanthine oxidase system. These results indicated the impressive antioxidant property of these two compounds.

scholarly journals The superoxide-dependent transfer of iron from ferritin to transferrin and lactoferrin

1988 ◽  
Vol 256 (3) ◽  
pp. 923-928 ◽  
Author(s):  
H P Monteiro ◽  
C C Winterbourn
Keyword(s):  
Lipid Peroxidation ◽  
Free Radicals ◽  
Xanthine Oxidase ◽  
Binding Protein ◽  
Gel Filtration ◽  
Iron Binding ◽  
Oxidase System ◽  
Oxidative Reactions ◽  
Phospholipid Liposomes ◽  
Iron Binding Protein

By the use of gel filtration and [59Fe]ferritin, apotransferrin and apolactoferrin were shown to take up iron released from ferritin by superoxide generated by hypoxanthine and xanthine oxidase. Apotransferrin also inhibited uptake of released iron by ferrozine. Ferritin and the xanthine oxidase system induced lipid peroxidation in phospholipid liposomes. This peroxidation was inhibited by apotransferrin or apolactoferrin. Thus, although superoxide and other free radicals can release iron from ferritin, either iron-binding protein, if present, should take up this iron and prevent its catalysing subsequent oxidative reactions.

Role of Lipid Peroxidation and Antioxidants in Gastric Mucosal Injury Induced by the Hypoxanthine-Xanthine Oxidase System in Rats

1997 ◽  
Vol 23 (2) ◽  
pp. 243-250 ◽  
Author(s):  
Toshikazu Yoshikawa ◽  
Yukiko Minamiyama ◽  
Hiroshi Ichikawa ◽  
Shuji Takahashi ◽  
Yuji Naito ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Xanthine Oxidase ◽  
Mucosal Injury ◽  
Gastric Mucosal Injury ◽  
Oxidase System
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