scholarly journals Osteosarcoma arising in a case of osteofibrous dysplasia of tibia with classic adamantinoma: A case report and literature review

2021 ◽  
Vol 28 ◽  
pp. 221049172110258
Author(s):  
Weiguo Li ◽  
Ka-Lok Mak ◽  
Tsz W Yau ◽  
Tit L Lam ◽  
Chak L Chan ◽  
...  

A five-year-old boy presented with left tibial swelling; there was a typical radiological feature of osteofibrous dysplasia. He was observed until the age of 14 years; there was development of aggressive radiological features. Biopsy revealed chondroblastic osteosarcoma. It was excised and the histology revealed chondroblastic osteosarcoma. A small lesion distal to the main tumour revealed adamantinoma within a background of feature of osteofibrous dysplasia. Proximally, feature of osteofibrous dysplasia was identified focally. The finding of adamantinoma over the distal part of the lesion supports that feature of osteofibrous dysplasia may be a precursor of adamantinoma. They may be a spectrum of diseases with multistep neoplastic transformation. The osteosarcoma may be a result of de-differentiation from adamantinoma. This case is remarkable as the patient was only 14 years old and the tumour showed typical features of osteosarcoma, with feature of osteofibrous dysplasia and adamantinoma found in the same specimen. Feature of osteofibrous dysplasia may be a precursor of adamantinoma, and adamantinoma may dedifferentiate into osteosarcoma.

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Rocco Salvatore Calabrò ◽  
Letteria Spadaro ◽  
Angela Marra ◽  
Placido Bramanti

Fahr’s disease (FD) is characterized by sporadic or familiar idiopathic calcification of the basal ganglia, dentate nuclei of the cerebellum, and centrum semiovale, mainly presenting with movement disorder, dementia, and behavioral abnormalities. We described a rare case of Fahr’s disease presenting at onset only with behavioral and neuropsychological alterations, whose diagnosis was supposed only after a brain CT, which showed extensive bilateral calcifications in the dentate nuclei of the cerebellum and basal ganglia. Since the onset of Fahr’s disease may be a dysexecutive syndrome with behavioral abnormalities, the clinical and radiological features are really important to do the appropriate diagnosis.


2021 ◽  
pp. 014556132110331
Author(s):  
Imen Achour ◽  
Ines Kharrat ◽  
Wadii Thabet ◽  
Basma Souissi ◽  
Malek Mnejja ◽  
...  

Pseudoaneurysms of facial artery usually arise from the distal part of the vessel. Only 4 cases were described in the literature involving the proximal part of facial artery. We present a case of a traumatic pseudoaneurysm involving the proximal part of facial artery. A 50-year-old man was referred to our department for a progressively growing submandibular mass. He was injured by a sharp object during a car crash 30 days ago. After 3 weeks, the patient noted the appearance of a subcutaneous mass in the left submandibular area. Physical examination revealed a freely movable, painful, and pulsatile swelling. Ultrasound and computerized tomography scan showed a nodular lesion in the left submandibular area in continuity with the facial artery. The diagnosis of pseudoaneurysm of facial artery was suspected. The patient was treated by surgery. The pseudoaneurysm was resected with ligation of the proximal and distal ends of the facial artery.


2015 ◽  
Vol 10 (6) ◽  
pp. 3573-3576 ◽  
Author(s):  
YI-FEI ZHENG ◽  
JUN LIN ◽  
HUI-LIN YANG

1997 ◽  
Vol 111 (7) ◽  
pp. 656-658 ◽  
Author(s):  
O. G. B. Nwaorgu ◽  
E. E. U. Akang ◽  
B. M. Ahmad ◽  
F. N. Nwachokor ◽  
A. N. Olu-Eddo

AbstractThe relative rarity of pharyngeal lipomas and paucity of clinical manifestations in the early stages of tumour growth conspire to task the diagnostic acumen of the clinician. A high index of suspicion and meticulous examination are essential in order to arrive at the diagnosis, which may be achieved pre-operatively by computerized axial tomography, revealing a mass lesion with a characteristic low attenuation value. A case of pharyngeal chondrolipoma in a 25-year-old male is reported. It is suggested that this conceptually intriguing and rarely encountered lesion can be explained on the basis of neoplastic transformation of the second to fourth pharyngeal cleft mesenchymal rests displaying both adipose and cartilaginous differentiation. Alternatively, the cartilage could represent vestigial remnants of non-neoplastic pharyngeal cleft tissue entrapped within a primarily lipomatous neoplasm. Slow growth may occur over a period of several years, prior to overt clinical manifestation.


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