Pharyngeal lipoma with cartilaginous metaplasia (chondrolipoma): a case report and literature review

1997 ◽  
Vol 111 (7) ◽  
pp. 656-658 ◽  
Author(s):  
O. G. B. Nwaorgu ◽  
E. E. U. Akang ◽  
B. M. Ahmad ◽  
F. N. Nwachokor ◽  
A. N. Olu-Eddo
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Tumour Growth ◽  
Slow Growth ◽  
Clinical Manifestations ◽  
Neoplastic Transformation ◽  
Axial Tomography ◽  
Computerized Axial Tomography ◽  
Relative Rarity ◽  
High Index Of Suspicion

AbstractThe relative rarity of pharyngeal lipomas and paucity of clinical manifestations in the early stages of tumour growth conspire to task the diagnostic acumen of the clinician. A high index of suspicion and meticulous examination are essential in order to arrive at the diagnosis, which may be achieved pre-operatively by computerized axial tomography, revealing a mass lesion with a characteristic low attenuation value. A case of pharyngeal chondrolipoma in a 25-year-old male is reported. It is suggested that this conceptually intriguing and rarely encountered lesion can be explained on the basis of neoplastic transformation of the second to fourth pharyngeal cleft mesenchymal rests displaying both adipose and cartilaginous differentiation. Alternatively, the cartilage could represent vestigial remnants of non-neoplastic pharyngeal cleft tissue entrapped within a primarily lipomatous neoplasm. Slow growth may occur over a period of several years, prior to overt clinical manifestation.

Epidermoid brain cysts: a case report and a literature review

2021 ◽  
pp. 358-371
Author(s):  
Maksim Vladimirovich Shpagin ◽  
Anton Viktorovich Yarikov ◽  
Denis Nikolaevich Nikitin ◽  
Igor Anatolievich Lobanov ◽  
Ivan Aleksandrovich Laganin ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Cerebellopontine Angle ◽  
Clinical Manifestations ◽  
Complex Treatment ◽  
Brain Pathology ◽  
Epidermoid Cysts ◽  
Histological Picture ◽  
Clinical Observations ◽  
Brain Cysts

The article is devoted to rare brain pathology, i.e. epidermoid cysts. The histological picture of the tumor is described; the classification is given. On the basis of our own clinical observations and a literature review, the features of the clinical manifestations of cholesteatoma of the cerebellopontine angle, modern approaches to the diagnosis and tactics of complex treatment are presented.

scholarly journals Osteosarcoma arising in a case of osteofibrous dysplasia of tibia with classic adamantinoma: A case report and literature review

2021 ◽  
Vol 28 ◽  
pp. 221049172110258
Author(s):  
Weiguo Li ◽  
Ka-Lok Mak ◽  
Tsz W Yau ◽  
Tit L Lam ◽  
Chak L Chan ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Distal Part ◽  
Neoplastic Transformation ◽  
Radiological Feature ◽  
Small Lesion ◽  
Osteofibrous Dysplasia ◽  
Radiological Features ◽  
Chondroblastic Osteosarcoma

A five-year-old boy presented with left tibial swelling; there was a typical radiological feature of osteofibrous dysplasia. He was observed until the age of 14 years; there was development of aggressive radiological features. Biopsy revealed chondroblastic osteosarcoma. It was excised and the histology revealed chondroblastic osteosarcoma. A small lesion distal to the main tumour revealed adamantinoma within a background of feature of osteofibrous dysplasia. Proximally, feature of osteofibrous dysplasia was identified focally. The finding of adamantinoma over the distal part of the lesion supports that feature of osteofibrous dysplasia may be a precursor of adamantinoma. They may be a spectrum of diseases with multistep neoplastic transformation. The osteosarcoma may be a result of de-differentiation from adamantinoma. This case is remarkable as the patient was only 14 years old and the tumour showed typical features of osteosarcoma, with feature of osteofibrous dysplasia and adamantinoma found in the same specimen. Feature of osteofibrous dysplasia may be a precursor of adamantinoma, and adamantinoma may dedifferentiate into osteosarcoma.

scholarly journals Ornidazole-Induced Recurrent Encephalopathy in a Chinese Man: A Rare Case Report and Literature Review

2021 ◽  
Vol 12 ◽  
Author(s):  
Rong Tang ◽  
Jia Liang ◽  
Yuanfang Li ◽  
Tingting Wu ◽  
Yuhao Zhang ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Corpus Callosum ◽  
Cerebellar Ataxia ◽  
Drug Withdrawal ◽  
Clinical Manifestations ◽  
Good Prognosis ◽  
Drug Discontinuation ◽  
Imaging Features ◽  
Mental Symptoms

Ornidazole-induced encephalopathy (OIE) is seldom seen in the clinic. In this study, we report a new case of a patient who had taken 1,000 mg ornidazole daily for nearly 4 years because of suspected diarrhea and proctitis and presented with subacute symptoms such as unsteady gait, slurred speech, and psychiatric disorder. These symptoms were significantly relieved 3 days after the patient stopped taking ornidazole. When he took this medicine again, however, similar symptoms occurred 4 months later, which were again reduced after 4 days of drug discontinuation. After the second onset, abnormal signals were identified around the aqueduct of the midbrain, around the fourth ventricle, and in the dentate nuclei of the cerebellum bilaterally. After 9 days of drug discontinuation, lesions disappeared in the magnetic resonance imaging (MRI) results. According to the clinical manifestations, imaging features, and the reduced symptoms after drug withdrawal, we clinically diagnosed the patient with OIE. This paper also reviews the literature on OIE. Only five cases (including our case) have been reported, all of whom presented with cerebellar ataxia and dysarthria and three with additional mental symptoms such as agitation and irritability. All five patients had abnormal lesions in the dentate nucleus of the cerebellum bilaterally, among whom four also had lesions in the corpus callosum and three around the periaqueduct of the midbrain. After withdrawal of ornidazole, the symptoms in all patients vanished or were alleviated, and three of them showed reduced or disappeared lesions in a head MRI reexamination. Overall, OIE has rarely been reported. Our case report and literature review show that the lesions in the cerebellum, corpus callosum, and brainstem can be reversed. The main manifestations of the lesions—cerebellar ataxia, dysarthria, and mental symptoms—quickly weaken or disappear after drug withdrawal, with good prognosis. Nevertheless, clear pathogenesis has yet to be further investigated.

scholarly journals Arthritis in children with LRBA deficiency – case report and literature review

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Rotem Semo Oz ◽  
Melissa S. Tesher
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Rheumatic Disease ◽  
Case Reports ◽  
Clinical Manifestations ◽  
Immune Dysregulation ◽  
Joint Involvement ◽  
Female Ratio ◽  
Minimal Data ◽  
Lrba Deficiency

Abstract Background Lipopolysaccharide (LPS)-responsive and beige like anchor (LRBA) deficiency is categorized as a subtype of common variable immune deficiency (CVID). A growing number of case reports and cohorts reveal a broad spectrum of clinical manifestations and variable phenotype expression, including immune dysregulation, enteropathy and recurrent infections. The association between rheumatic disease and CVID generally has been well established, arthritis has been less frequently reported and minimal data regarding its clinical features and characteristic in LRBA deficiency has been published. This case report and literature review evaluates the characteristics and features of arthritis in LRBA deficiency patients. Case presentation and review results Herein, we describe a unique case of LRBA deficiency first presented with poly articular arthritis. Alongside the report, a literature review focusing on LRBA deficiency, rheumatic disease and arthritis has been conducted. We reviewed 43 publications. Among these, 7 patients were identified with arthritis. Age of first presentation was six weeks to 3 years. Male to female ratio was 4/3. Two patients were diagnosed with polyarticular Juvenile idiopathic arthritis (JIA) and three with oligoarticular JIA. Each patient was found to have different genomic mutation. The treatment was diverse and included corticosteroids, cyclosporine, methotrexate, adalidumab and abatacept. Conclusion Joint involvement is variable in LRBA deficiency, hence it should always be kept in mind as a differential diagnosis for a patient with combination of juvenile arthritis and clinically atypical immune dysregulation and / or immunodeficiency.

scholarly journals Disseminated Histoplasmosis in an Elderly Man Presented with Fever, Weight loss, Abdominal Pain and Haemoptysis - A Case Report with Literature Review

2011 ◽  
Vol 12 (1) ◽  
pp. 81-85
Author(s):  
Mohammad Robed Amin ◽  
Farzana Shumi ◽  
Hasibuddin Khan ◽  
Syed Ahmed Abdullah ◽  
Shafiul Alam ◽  
...  
Keyword(s):  
Elderly Patient ◽  
Weight Loss ◽  
Abdominal Pain ◽  
Case Report ◽  
Literature Review ◽  
Disseminated Histoplasmosis ◽  
History Of ◽  
Background History ◽  
Recurrent Haemoptysis ◽  
High Index Of Suspicion

An elderly patient presented with prolonged fever, gross weight loss, recurrent haemoptysis and abdominal pain. He had a background history of adrenal tuberculosis with completion of treatment without any obvious improvement. Clinically he was diagnosed as a case of adrenocotical insufficiency. Evaluation including histopathology revealed the diagnosis as disseminated histoplasmosis involving adrenal gland and lungs. The disease is a rarity without any underneath immunosuppression and hence high index of suspicion with appropriate steps for investigation is the key to achieve a diagnosis of disseminated histoplasmosis in Bangladesh. Keyword: . DOI: 10.3329/jom.v12i1.6936J Medicine 2011; 12 : 81-85

Congenital total absence of the pericardium: A case report

Open Medicine ◽  
2010 ◽  
Vol 5 (3) ◽  
pp. 315-317
Author(s):  
Arezou Zoroufian ◽  
Shapour Shirani ◽  
Behareh Eslami ◽  
Mohammad Sahebjam
Keyword(s):  
Physical Activity ◽  
Case Report ◽  
Chest Pain ◽  
Congenital Heart ◽  
Axial Tomography ◽  
Atypical Chest Pain ◽  
Total Absence ◽  
History Of ◽  
Computerized Axial Tomography ◽  
Tomography Scan

AbstractWe report the case of a 52-year-old woman who presented with a several-year history of palpitation (exacerbated by emotional stress and physical activity) and recent development of atypical chest pain. An investigation was undertaken to diagnose the patient’s problem and to recommend the best possible therapy. Transthoracic echocardiography and a computerized axial tomography scan showed evidence of complete absence of the pericardium, which is a rare congenital heart defect.

scholarly journals Neuro-Behçet’s masquerading as progressive bulbar palsy: a case report and literature review

JRSM Open ◽  
2019 ◽  
Vol 10 (1) ◽  
pp. 205427041983484
Author(s):  
Theodoros Paschalis ◽  
Noor M Shami ◽  
Amit KJ Mandal ◽  
Constantinos G Missouris
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Improve Outcome ◽  
Behcet's Disease ◽  
Bulbar Palsy ◽  
High Index Of Suspicion ◽  
Prompt Diagnosis

In patients with progressive bulbar palsy without an obvious cause, there should be a high index of suspicion for the potential diagnosis of Neuro-Behçet’s Disease, even in the absence of the acute classical peripheral manifestations of Bechet’s Disease, with emphasis in prompt diagnosis using ‘The International Criteria for Behçet’s Disease’ and rapid, effective treatment in order to improve outcome.

Middle turbinate osteoma; an unusual cause of nasal obstruction

1988 ◽  
Vol 102 (4) ◽  
pp. 359-361 ◽  
Author(s):  
H. B. Whittet ◽  
R. E. Quiney
Keyword(s):  
Case Report ◽  
Nasal Obstruction ◽  
Surgical Approach ◽  
Middle Turbinate ◽  
Complete Removal ◽  
Lateral Rhinotomy ◽  
Radiological Assessment ◽  
Axial Tomography ◽  
Computerized Axial Tomography ◽  
Benign Tumours

AbstractOsteomas are common benign tumours of the paranasal sinuses, but are usually asymptomatic and found as a coincidental finding during routine radiological investigations. We present a case report of a patient with an isolated osteoma of the middle turbinate presenting with unilateral nasal obstruction which required removal via a lateral rhinotomy approach. The aetiology, pathology and presenting features of these tumours are reviewed and their subsequent management discussed. In particular, adequate pre-operative radiological assessment to determine involvement of the cribriform plate region by computerized axial tomography (CAT Scanning) is emphasized since this may indicate the need for a cranio-facial surgical approach rather than a lateral rhinotomy to achieve complete removal.

scholarly journals UNILATERAL PYODERMA GANGRENOSUM OF THE EXTERNAL EAR IN A RESOURCE LIMITED SETTING: CASE REPORT AND LITERATURE REVIEW

2020 ◽  
Author(s):  
Zephania Abraham ◽  
Edwin Thomas ◽  
Aveline Kahinga
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Pyoderma Gangrenosum ◽  
Resource Limited Setting ◽  
Neutrophilic Dermatosis ◽  
External Ear ◽  
Prompt Treatment ◽  
Resource Limited ◽  
High Index Of Suspicion ◽  
Limited Setting

Pyoderma gangrenosum (PG) being a primary sterile neutrophilic dermatosis, the etiology is still uncertain and it rarely affects children. A high index of suspicion is essential to execute its prompt treatment. To the best of our knowledge this is the first reported case in our country

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