scholarly journals Zinc Level and Its Role in Recurrent Clostridium difficile Infection: A Case Report and Literature Review

2020 ◽  
Vol 8 ◽  
pp. 232470962094131
Author(s):  
Swetha Parvataneni ◽  
Avinash R. Dasari
Keyword(s):  
United States ◽  
Case Report ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Zinc Supplementation ◽  
The United States ◽  
Zinc Level ◽  
Recurrence Rates ◽  
Oral Transmission ◽  
Recurrent Clostridium Difficile Infection

Clostridium difficile infection is a common nosocomial infection in US hospitals, accounting for approximately 12 800 deaths annually in the United States. These infections are often associated with the use of antibiotics, which can alter the gut microbiome and thus render patients susceptible to C difficile infection. C difficile is often spread via fecal oral transmission. Multiple medications have been developed, but recurrence rates reach 60% after treatment. Recent data have shown that zinc supplementation decreases the recurrence of C difficile infection. In this article, we present a case of recurrent C difficile infection with zinc deficiency in which zinc supplementation improved the symptoms and reduced the incidence of recurrence.

scholarly journals The Co-Seasonality of Pneumonia and Influenza With Clostridium difficile Infection in the United States, 1993-2008

2013 ◽  
Vol 178 (1) ◽  
pp. 118-125 ◽  
Author(s):  
K. A. Brown ◽  
N. Daneman ◽  
P. Arora ◽  
R. Moineddin ◽  
D. N. Fisman
Keyword(s):  
United States ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
The United States

scholarly journals Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)

2018 ◽  
Vol 66 (7) ◽  
pp. 987-994 ◽  
Author(s):  
L Clifford McDonald ◽  
Dale N Gerding ◽  
Stuart Johnson ◽  
Johan S Bakken ◽  
Karen C Carroll ◽  
...  
Keyword(s):  
United States ◽  
Clinical Practice ◽  
Clostridium Difficile ◽  
Infectious Diseases ◽  
Clostridium Difficile Infection ◽  
The United States ◽  
Healthcare Associated Infection ◽  
Adults And Children ◽  
Healthcare Associated ◽  
Healthcare Epidemiology

Abstract A panel of experts was convened by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA) to update the 2010 clinical practice guideline on Clostridium difficile infection (CDI) in adults. The update, which has incorporated recommendations for children (following the adult recommendations for epidemiology, diagnosis, and treatment), includes significant changes in the management of this infection and reflects the evolving controversy over best methods for diagnosis. Clostridium difficile remains the most important cause of healthcare-associated diarrhea and has become the most commonly identified cause of healthcare-associated infection in adults in the United States. Moreover, C. difficile has established itself as an important community pathogen. Although the prevalence of the epidemic and virulent ribotype 027 strain has declined markedly along with overall CDI rates in parts of Europe, it remains one of the most commonly identified strains in the United States where it causes a sizable minority of CDIs, especially healthcare-associated CDIs. This guideline updates recommendations regarding epidemiology, diagnosis, treatment, infection prevention, and environmental management.

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