Binding of biotin to hepatitis B surface antigen: a possible pitfall in immunohistochemistry.
1989 ◽
Vol 37
(4)
◽
pp. 551-554
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Keyword(s):
B Virus
◽
We report on the binding of biotin, and hence of biotinylated antibodies and lectins, to ground glass hepatocytes and liver cell membranes in chronic hepatitis B viral infection. This binding is of low affinity, and was proved to be directed at the hepatitis B surface antigen, presumably at its disulfide bonds. To avoid false-positive results, this affinity should be considered in the interpretation of immunohistochemical stainings of hepatitis B virus-infected liver tissue with biotinylated reagents.
2012 ◽
Vol 32
(6)
◽
pp. 420-425
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2010 ◽
Vol 8
(6)
◽
pp. 717-726
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2013 ◽
Vol 127
(11)
◽
pp. 1065-1066
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1986 ◽
Vol 23
(4)
◽
pp. 797-799
◽
2005 ◽
Vol 20
(3)
◽
pp. 433
◽
2015 ◽
Vol 48
(2)
◽
pp. S36
2001 ◽
Vol 52
(2)
◽
pp. 117-123
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Keyword(s):