PROGRESSIVE DISSEMINATED HISTOPLASMOSIS 10 YEARS AFTER RETURN OUT OF AFRICA IN AN IMMUNOCOMPETENT HOST

2004 ◽  
Vol 59 (5) ◽  
pp. 274-278 ◽  
Author(s):  
P. Desmet ◽  
D. Vogelaers ◽  
M. Afschrift
Keyword(s):  
Immunocompetent Host ◽  
Disseminated Histoplasmosis ◽  
Progressive Disseminated Histoplasmosis ◽  
Out Of Africa

Treatment Of Disseminated Histoplasmosis With Ethyl Vanillate

PEDIATRICS ◽  
1951 ◽  
Vol 7 (1) ◽  
pp. 7-18
Author(s):  
AMOS CHRISTIE ◽  
JAMES G. MIDDLETON ◽  
J. CYRIL PETERSON ◽  
DAVID L. MCVICKAR
Keyword(s):  
Disseminated Histoplasmosis ◽  
Progressive Disseminated Histoplasmosis

Some of the physical and pharmacologic properties of ethyl vanillate, a new fungistatic or fungicidal agent, have been briefly stated. The records of 12 patients with progressive disseminated histoplasmosis treated with ethyl vanillate have been reviewed. Five of these patients are alive and apparently well following treatment, an experience not previously encountered or reported in the literature. The use of the drug in the treatment of histoplasmosis has been outlined and the toxic manifestations of overdosage have been described.

scholarly journals Bats, Fever and Adenopathy – What Is the Link?

2013 ◽  
Vol 24 (1) ◽  
pp. 35-37 ◽  
Author(s):  
Joshua J Manolakos ◽  
Mohan Cooray ◽  
Ameen Patel ◽  
Shariq Haider
Keyword(s):  
Costa Rica ◽  
Environmental Exposure ◽  
Salvage Therapy ◽  
Histoplasma Capsulatum ◽  
Treatment Options ◽  
Diagnostic Approach ◽  
Disseminated Histoplasmosis ◽  
Progressive Disseminated Histoplasmosis

A case of travel-related, subacute, progressive disseminated histoplasmosis in a nonimmunocompromised individual is described. The present case highlights the environmental exposure toHistoplasma capsulatumin Costa Rica, the diagnostic approach and treatment options, as well as new alternatives for salvage therapy for histoplasmosis infection.

scholarly journals Hemophagocytic Lymphohistiocytosis and Progressive Disseminated Histoplasmosis

2016 ◽  
Vol 22 (6) ◽  
pp. 1119-1121 ◽  
Author(s):  
Kenice Ferguson-Paul ◽  
Spencer Mangum ◽  
Ashley Porter ◽  
Vasiliki Leventaki ◽  
Patrick Campbell ◽  
...  
Keyword(s):  
Hemophagocytic Lymphohistiocytosis ◽  
Disseminated Histoplasmosis ◽  
Progressive Disseminated Histoplasmosis

scholarly journals Acute Disseminated Histoplasmosis with Atypical Lymphocytosis in an Immunocompetent Host

IDCases ◽  
2017 ◽  
Vol 7 ◽  
pp. 23-24 ◽  
Author(s):  
Ayman Elbadawi ◽  
Hamdy M.A. Ahmed ◽  
Hussain Adly ◽  
Mohamed A. Elkhouly ◽  
Samar Abohamed ◽  
...  
Keyword(s):  
Immunocompetent Host ◽  
Disseminated Histoplasmosis

scholarly journals Typical Facial Lesions: A Window of Suspicion for Progressive Disseminated Histoplasmosis—A Case of Asian Prototype

2016 ◽  
Vol 2016 ◽  
pp. 1-5
Author(s):  
Prasan K. Panda ◽  
Siddharth Jain ◽  
Rita Sood ◽  
Rajni Yadav ◽  
Naval K. Vikram
Keyword(s):  
Histoplasma Capsulatum ◽  
Bone Marrow Aspiration ◽  
Febrile Illness ◽  
Immunocompetent Patient ◽  
Dimorphic Fungus ◽  
Recent Onset ◽  
Disseminated Histoplasmosis ◽  
The Face ◽  
History Of ◽  
Progressive Disseminated Histoplasmosis

Histoplasmosis is caused by a dimorphic fungusHistoplasma capsulatumin endemic areas, mainly America, Africa, and Asia. In India, it is being reported from most states; however, it is endemic along the Ganges belt. We report a case of an apparently immunocompetent male who presented with 3-month history of fever, cough, and weight loss with recent onset odynophagia and had hepatosplenomegaly and mucocutaneous lesions over the face. The differential diagnosis of leishmaniasis, tuberculosis, leprosy, fungal infection, lymphoproliferative malignancy, and other granulomatous disorders was considered, but he succumbed to his illness. Antemortem skin biopsy and bone marrow aspiration along with postmortem liver, lung, and spleen biopsy showed disseminated histoplasmosis. This case highlights the need for an early suspicion of progressive disseminated histoplasmosis in the presence of classical mucocutaneous lesions even in an immunocompetent patient suffering from a febrile illness. Cure rate approaches almost 100% with early treatment, whereas it is universally fatal if left untreated.

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