The Genetic Revolution; Today's dream or tomorrow's nightmare?, New Edition, Dr. Patrick Dixon

1997 ◽  
Vol 3 (2) ◽  
pp. 32-32
Author(s):  
C. MacKellar
Keyword(s):  
Genetic Revolution

First casualties in the genetic revolution

2000 ◽  
Vol &NA; (1236) ◽  
pp. 3-4 ◽  
Author(s):  
Mark Greener
Keyword(s):  
Genetic Revolution

A Case Study - NeuBase Therapeutics, Inc.

2021 ◽  
Vol 26 (2) ◽  
Author(s):  
Dietrich A. Stephan
Keyword(s):  
Gene Function ◽  
Genetic Defects ◽  
New Class ◽  
Genetic Revolution

NeuBase is accelerating the genetic revolution by developing a new class of precision genetic medicines which can be designed to increase, decrease, or change gene function, as appropriate, to resolve genetic defects that drive disease.

The genetic revolution

2016 ◽  
pp. 285-306
Author(s):  
John C. Moskop
Keyword(s):  
Genetic Revolution

Preparing health professionals for the genetic revolution

JAMA ◽  
1997 ◽  
Vol 278 (15) ◽  
pp. 1285-1286 ◽  
Author(s):  
F. S. Collins
Keyword(s):  
Health Professionals ◽  
Genetic Revolution

scholarly journals Whole-exome sequencing and its impact in hereditary hearing loss

2015 ◽  
Vol 97 ◽  
Author(s):  
TAHIR ATIK ◽  
GUNEY BADEMCI ◽  
OSCAR DIAZ-HORTA ◽  
SUSAN H. BLANTON ◽  
MUSTAFA TEKIN
Keyword(s):  
Hearing Loss ◽  
Exome Sequencing ◽  
Whole Exome Sequencing ◽  
Hereditary Deafness ◽  
Whole Exome ◽  
Human Genes ◽  
Genetic Revolution ◽  
Recent Developments ◽  
Next Generation Sequencing Ngs ◽  
Generation Sequencing

SummaryNext-generation sequencing (NGS) technologies have played a central role in the genetic revolution. These technologies, especially whole-exome sequencing, have become the primary tool of geneticists to identify the causative DNA variants in Mendelian disorders, including hereditary deafness. Current research estimates that 1% of all human genes have a function in hearing. To date, mutations in over 80 genes have been reported to cause nonsyndromic hearing loss (NSHL). Strikingly, more than a quarter of all known genes related to NSHL were discovered in the past 5 years via NGS technologies. In this article, we review recent developments in the usage of NGS for hereditary deafness, with an emphasis on whole-exome sequencing.

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