Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium

Key Points Notch1 induction promotes specification of hemogenic endothelial cells during embryonic stem cell differentiation. Foxc2 functions downstream of Notch in specification of hemogenic endothelium in mouse and zebrafish embryos.

Download Full-text

Multiple Mesoderm Subsets Give Rise to Endothelial Cells, Whereas Hematopoietic Cells Are Differentiated Only from a Restricted Subset in Embryonic Stem Cell Differentiation Culture

Stem Cells ◽

10.1634/stemcells.2006-0809 ◽

2008 ◽

Vol 26 (2) ◽

pp. 401-411 ◽

Cited By ~ 34

Author(s):

Takumi Era ◽

Naoki Izumi ◽

Misato Hayashi ◽

Shinsuke Tada ◽

Satomi Nishikawa ◽

...

Keyword(s):

Endothelial Cells ◽

Stem Cell ◽

Cell Differentiation ◽

Embryonic Stem Cell ◽

Hematopoietic Cells ◽

Embryonic Stem ◽

Stem Cell Differentiation ◽

Embryonic Stem Cell Differentiation

Download Full-text

Endothelial Cells in Co-culture Enhance Embryonic Stem Cell Differentiation to Pancreatic Progenitors and Insulin-Producing Cells through BMP Signaling

Stem Cell Reviews and Reports ◽

10.1007/s12015-011-9232-z ◽

2011 ◽

Vol 7 (3) ◽

pp. 532-543 ◽

Cited By ~ 38

Author(s):

Dodanim Talavera-Adame ◽

Gordon Wu ◽

Yao He ◽

Tina T. Ng ◽

Ankur Gupta ◽

...

Keyword(s):

Endothelial Cells ◽

Stem Cell ◽

Cell Differentiation ◽

Embryonic Stem Cell ◽

Embryonic Stem ◽

Stem Cell Differentiation ◽

Bmp Signaling ◽

Embryonic Stem Cell Differentiation ◽

Pancreatic Progenitors ◽

Insulin Producing Cells

Download Full-text

A Chemical Small Molecule Induces Mouse Embryonic Stem Cell Differentiation into Functional Vascular Endothelial Cells via Hmbox1

Stem Cells and Development ◽

10.1089/scd.2012.0055 ◽

2012 ◽

Vol 21 (15) ◽

pp. 2762-2769 ◽

Cited By ~ 15

Author(s):

Lei Han ◽

Jing Shao ◽

Le Su ◽

Jiangang Gao ◽

Shengqing Wang ◽

...

Keyword(s):

Endothelial Cells ◽

Stem Cell ◽

Cell Differentiation ◽

Small Molecule ◽

Vascular Endothelial Cells ◽

Embryonic Stem ◽

Mouse Embryonic Stem Cell ◽

Stem Cell Differentiation ◽

Embryonic Stem Cell Differentiation ◽

Vascular Endothelial

Download Full-text

Embryonic Stem Cell Differentiation to Functional Arterial Endothelial Cells through Sequential Activation of ETV2 and NOTCH1 Signaling by HIF1α

Stem Cell Reports ◽

10.1016/j.stemcr.2017.07.001 ◽

2017 ◽

Vol 9 (3) ◽

pp. 796-806 ◽

Cited By ~ 16

Author(s):

Kit Man Tsang ◽

James S. Hyun ◽

Kwong Tai Cheng ◽

Micaela Vargas ◽

Dolly Mehta ◽

...

Keyword(s):

Endothelial Cells ◽

Stem Cell ◽

Cell Differentiation ◽

Embryonic Stem Cell ◽

Embryonic Stem ◽

Stem Cell Differentiation ◽

Embryonic Stem Cell Differentiation ◽

Notch1 Signaling ◽

Sequential Activation ◽

Arterial Endothelial Cells

Download Full-text

56 MicroRNAs 99b, 181a and 181b are induced during human embryonic stem cell differentiation to vascular endothelial cells and can enhance differentiation capacity upon differentiation

Heart ◽

10.1136/heartjnl-2011-300920b.56 ◽

2011 ◽

Vol 97 (20) ◽

pp. e7-e7 ◽

Cited By ~ 1

Author(s):

N. M. Kane ◽

L. Howard ◽

R. Khanin ◽

J. McClure ◽

C. Breen ◽

...

Keyword(s):

Endothelial Cells ◽

Stem Cell ◽

Cell Differentiation ◽

Embryonic Stem Cell ◽

Human Embryonic Stem Cell ◽

Vascular Endothelial Cells ◽

Embryonic Stem ◽

Stem Cell Differentiation ◽

Embryonic Stem Cell Differentiation ◽

Vascular Endothelial

Download Full-text

DNA methyltransferase inhibition induces mouse embryonic stem cell differentiation into endothelial cells

Experimental Cell Research ◽

10.1016/j.yexcr.2009.08.011 ◽

2010 ◽

Vol 316 (2) ◽

pp. 172-180 ◽

Cited By ~ 35

Author(s):

Saswati Banerjee ◽

Methode Bacanamwo

Keyword(s):

Endothelial Cells ◽

Stem Cell ◽

Cell Differentiation ◽

Embryonic Stem Cell ◽

Dna Methyltransferase ◽

Embryonic Stem ◽

Mouse Embryonic Stem Cell ◽

Stem Cell Differentiation ◽

Embryonic Stem Cell Differentiation

Download Full-text

The Roles of p38α MAP Kinase in the Regulation of Embryonic Stem Cell Differentiation to Endothelial Cells and Cardiomyocytes

The FASEB Journal ◽

10.1096/fasebj.22.1_supplement.524.1 ◽

2008 ◽

Vol 22 (S1) ◽

Author(s):

Yan‐Lin Guo ◽

Jianming Ye ◽

Faqing Huang

Keyword(s):

Endothelial Cells ◽

Stem Cell ◽

Cell Differentiation ◽

Embryonic Stem Cell ◽

Map Kinase ◽

Embryonic Stem ◽

Stem Cell Differentiation ◽

Embryonic Stem Cell Differentiation ◽

P38α Map Kinase

Download Full-text

3659 Induction of human embryonic stem cell-differentiation into cardiomyocytes

European Heart Journal ◽

10.1016/s0195-668x(03)96243-9 ◽

2003 ◽

Vol 24 (5) ◽

pp. 715 ◽

Cited By ~ 1

Author(s):

R HASSINK

Keyword(s):

Stem Cell ◽

Cell Differentiation ◽

Embryonic Stem Cell ◽

Human Embryonic Stem Cell ◽

Embryonic Stem ◽

Stem Cell Differentiation ◽

Embryonic Stem Cell Differentiation

Download Full-text

Faculty Opinions recommendation of Characterization of mesendoderm: a diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1027905.335856 ◽

2005 ◽

Author(s):

Stephen Dalton

Keyword(s):

Stem Cell ◽

Cell Differentiation ◽

Embryonic Stem Cell ◽

Embryonic Stem ◽

Stem Cell Differentiation ◽

Definitive Endoderm ◽

Embryonic Stem Cell Differentiation

Download Full-text

Faculty Opinions recommendation of MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1126885.584330 ◽

2008 ◽

Author(s):

Peter Sarnow ◽

Cara Pager

Keyword(s):

Stem Cell ◽

Cell Differentiation ◽

Embryonic Stem Cell ◽

Embryonic Stem ◽

Stem Cell Differentiation ◽

Embryonic Stem Cell Differentiation ◽

Coding Regions

Download Full-text