Comparison of serum and urine cotinine level according to stage exhaled CO in smokers

2021 ◽  
Author(s):  
Kristo Kurniawan ◽  
Triwahju Astuti ◽  
Teguh Rahayu Sartono
Keyword(s):  
Cotinine Level ◽  
Urine Cotinine ◽  
Serum And Urine

scholarly journals A Brief Exposure to Moderate Passive Smoke Increases Metabolism and Thyroid Hormone Secretion

2007 ◽  
Vol 92 (1) ◽  
pp. 208-211 ◽  
Author(s):  
Giorgos S. Metsios ◽  
Andreas D. Flouris ◽  
Athanasios Z. Jamurtas ◽  
Andres E. Carrillo ◽  
Demetrios Kouretas ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Passive Smoking ◽  
Repeated Measures ◽  
Hormone Secretion ◽  
Free T4 ◽  
Hormone Levels ◽  
Urine Cotinine ◽  
The Mean ◽  
Thyroid Hormone Levels ◽  
Serum And Urine

Abstract Context: Active smoking influences normal metabolic status and thyroid function. Objective: The objective was to assess experimentally the effects of 1 h of moderate passive smoking in a controlled simulated bar/restaurant environment on the metabolism and thyroid hormone levels in healthy nonsmokers. Participants: Eighteen (nine females, nine males) healthy individuals (mean ± sd: age, 25.3 ± 3.1 yr; height, 174.0 ± 10.1 cm; weight, 65.2 ± 13.7 kg) participated in the study. Design: In repeated-measures randomized blocks, participants visited the laboratory on 2 consecutive days. In the experimental condition, they were exposed to 1 h of moderate passive smoking at a carbon monoxide concentration of 23 ± 1 ppm in an environmental chamber, whereas in the control condition participants remained in the same chamber for 1 h breathing normal atmospheric air. Main Outcome Measures: In both conditions, cotinine serum and urine levels, resting energy expenditure (REE), as well as concentration of T3, free T4, and TSH were assessed before participants entered the chamber and immediately after their exit. Heart rate and blood pressure were tested in 10-min intervals during all REE assessments. Results: The mean ± sd difference of serum and urine cotinine levels (−0.27 ± 3.94 vs. 14.01 ± 6.54 and 0.05 ± 2.07 vs. 7.23 ± 3.75, respectively), REE (6.73 ± 98.06 vs. 80.58 ± 120.91) as well as T3 and free T4 (0.05 ± 0.11 vs. 0.13 ± 0.12 and 0.02 ± 0.15 vs. 0.22 ± 0.20) were increased in the experimental compared with the control condition at baseline and follow-up (P < 0.05). No statistically significant variation was observed in the mean difference of the remaining parameters (P > 0.05). Serum and urine cotinine values were linearly associated with REE (P < 0.05). Conclusion: One hour of passive smoking at bar/restaurant levels is accompanied by significant increases in metabolism and thyroid hormone levels.

Variation of Serum and Urine Cotinine in Passive and Active Smokers and Applicability in Preconceptional Smoking Cessation Counseling

2002 ◽  
Vol 90 (2) ◽  
pp. 119-124 ◽  
Author(s):  
Sabina de Weerd ◽  
Chris M.G. Thomas ◽  
Josien E.T.G. Kuster ◽  
Rolf J.L.M. Cikot ◽  
Eric A.P. Steegers
Keyword(s):  
Smoking Cessation ◽  
Smoking Cessation Counseling ◽  
Urine Cotinine ◽  
Serum And Urine

scholarly journals Effect of parental smoking on their children’s urine cotinine level in Korea: A population-based study

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0248013
Author(s):  
Myung-Bae Park ◽  
Chhabi Lal Ranabhat
Keyword(s):  
Linear Regression Analysis ◽  
Smoking Habit ◽  
Parental Smoking ◽  
Analysis Of Covariance ◽  
Health Examination ◽  
Group Diff ◽  
Cotinine Level ◽  
Urine Cotinine ◽  
Smoking Exposure ◽  
Cotinine Concentration

Background Children may be exposed to tobacco products in multiple ways if their parents smoke. The risks of exposure to secondhand smoke (SHS) are well known. This study aimed to investigate the association between parental smoking and the children’s cotinine level in relation to restricting home smoking, in Korea. Methods Using the Korea National Health and Nutrition Health Examination Survey data from 2014 to 2017, we analyzed urine cotinine data of parents and their non-smoking children (n = 1,403), in whose homes parents prohibited smoking. We performed linear regression analysis by adjusting age, sex, house type, and household income to determine if parent smoking was related to the urine cotinine concentration of their children. In addition, analysis of covariance and Tukey’s post-hoc tests were performed according to parent smoking pattern. Finding Children’s urine cotinine concentrations were positively associated with those of their parents. Children of smoking parents had a significantly higher urine cotinine concentration than that in the group where both parents are non-smokers (diff = 0.933, P < .0001); mothers-only smoker group (diff = 0.511, P = 0.042); and fathers-only smoker group (diff = 0.712, P < .0001). In the fathers-only smoker group, the urine cotinine concentration was significantly higher than that in the group where both parents were non-smoker (diff = 0.221, P < .0001), but not significantly different compared to the mothers-only smoker group (diff = - -0.201, P = 0.388). Children living in apartments were more likely to be exposed to smoking substances. Conclusion This study showed a correlation between parents’ and children’s urine cotinine concentrations, supporting the occurrence of home smoking exposure due to the parents’ smoking habit in Korea. Although avoiding indoor home smoking can decrease the children’s exposure to tobacco, there is a need to identify other ways of smoking exposure and ensure appropriate monitoring and enforcement of banning smoking in the home.

scholarly journals Assessing tobacco use in an African population: Serum and urine cotinine cut-offs from South Africa

2019 ◽  
Vol 195 ◽  
pp. 82-89 ◽  
Author(s):  
Lisa J. Ware ◽  
Karen Charlton ◽  
Ruan Kruger ◽  
Yolandi Breet ◽  
Johannes van Rooyen ◽  
...  
Keyword(s):  
South Africa ◽  
Tobacco Use ◽  
African Population ◽  
Urine Cotinine ◽  
Serum And Urine

A Plan of Group Therapy for Smoking Cessation in Patients Suffering From Buerger's Disease: A Case Series Study in Northeast Iran

2009 ◽  
Vol 4 (1) ◽  
pp. 42-47 ◽  
Author(s):  
Bahare Fazeli ◽  
Hamidreza Arshadi
Keyword(s):  
Smoking Cessation ◽  
Group Therapy ◽  
Cognitive Model ◽  
Case Series ◽  
Educational Status ◽  
Buerger’S Disease ◽  
Buerger's Disease ◽  
Cotinine Level ◽  
Urine Cotinine ◽  
Case Series Study

AbstractIntroduction: Buerger's disease (BD) is a chronic peripheral vascular disease that affects the young smokers from low socioeconomic backgrounds. The only effective therapy for this disease is smoking cessation; otherwise the outcome of BD will be several amputations. Aims & Methods: Via 12 sessions, an elective pattern of group therapy was designed and tried with six volunteer patients. The therapy commenced with motivation, mixed with a behavioural and cognitive model appropriate to the patients' socioeconomic and educational status. Two extra training sessions of apposite and supporting behaviour were allocated for their family members. Urine cotinine level was measured before and after the group therapy. The aim of study was to lead the patients towards a self-help group. Results: A partial remission of the disease in one patient and a complete remission in four patients were the consequences of the present study. The average decline of urine cotinine level was about two ranks. One patient was not helped. Conclusion: Although the study faced major loss of subjects, in regards to dramatic changes in urine cotinine level, this plan of group therapy seems to be an effective and cost-effective option for clinical improvement in patients with BD, as a chronic and smoking-related disease.

Exposure to environmental tobacco smoke measured by cotinine 125I-radioimmunoassay.

1989 ◽  
Vol 35 (6) ◽  
pp. 1036-1039 ◽  
Author(s):  
G J Knight ◽  
G E Palomaki ◽  
D H Lea ◽  
J E Haddow
Keyword(s):  
Quality Control ◽  
Lower Limit ◽  
Environmental Tobacco Smoke ◽  
Tobacco Smoke ◽  
Polyclonal Antiserum ◽  
Standard Curve ◽  
Passive Exposure ◽  
Urine Cotinine ◽  
Serum And Urine

Abstract We describe a polyclonal-antiserum-based 125I-radioimmunoassay for cotinine that is suitable for measuring nonsmokers' passive exposure to tobacco smoke in the environment. The standard curve ranged from 0.25 to 12.0 micrograms/L, with an estimated lower limit of sensitivity of 0.2 microgram/L (95% B/Bo = 0.2 microgram/L; 50% B/Bo = 4.0 micrograms/L). The median within-assay CVs for patients' samples with cotinine values from 0.4 to 1.3, 1.4 to 2.4, 2.5 to 4.6, and 4.7 to 15.6 micrograms/L were 13.9%, 7.2%, 5.1%, and 5.7%, respectively. Between-assay CVs for two quality-control sera with average values of 1.53 and 3.68 micrograms/L were 14.3% and 7.8%, respectively. Analytical recoveries of cotinine from smokers' sera diluted in zero calibrant ranged from 91% to 116%. Cotinine values determined on 79 paired sera and urines from nonsmokers showed significant correlation with self-reported exposure to environmental tobacco smoke (r = 0.49, P less than 0.001 for sera; r = 0.57, P less than 0.001 for urine). The log of the values for serum and urine cotinine were also significantly correlated (r = 0.85, P less than 0.001). Evidently, polyclonal antiserum can be used to develop a cotinine assay for measuring exposure to environmental tobacco smoke that compares well with that described for monoclonal-based assays.

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