Comparative analysis of central aortic blood pressure, pulse wave velocity, and other indicators of arterial stiffness in patients with obstructive pulmonary diseases in Indian population

2021 ◽  
Author(s):  
Jyoti Bajpai ◽  
Surya Kant ◽  
Akshyaya Pradhan ◽  
Ajay Verma ◽  
Darshan Bajaj
Keyword(s):  
Blood Pressure ◽  
Comparative Analysis ◽  
Arterial Stiffness ◽  
Indian Population ◽  
Pressure Pulse ◽  
Pulse Wave ◽  
Pulmonary Diseases ◽  
Aortic Blood ◽  
Aortic Blood Pressure ◽  
Central Aortic Blood Pressure

Volume status and arterial blood pressures are associated with arterial stiffness in hemodialysis patients

2018 ◽  
Vol 41 (7) ◽  
pp. 378-384 ◽  
Author(s):  
Alper Erdan ◽  
Abdullah Ozkok ◽  
Nadir Alpay ◽  
Vakur Akkaya ◽  
Alaattin Yildiz
Keyword(s):  
Blood Pressure ◽  
Arterial Stiffness ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Pressure ◽  
Pulse Wave ◽  
Augmentation Index ◽  
Mean Blood Pressure ◽  
Aortic Blood ◽  
Aortic Blood Pressure

Background: Arterial stiffness is a strong predictor of mortality in hemodialysis patients. In this study, we aimed to investigate possible relations of arterial stiffness with volume status determined by bioimpedance analysis and aortic blood pressure parameters. Also, effects of a single hemodialysis session on these parameters were studied. Methods: A total of 75 hemodialysis patients (M/F: 43/32; mean age: 53 ± 17) were enrolled. Carotid-femoral pulse wave velocity, augmentation index, and aortic pulse pressure were measured by applanation tonometry before and after hemodialysis. Extracellular fluid and total body fluid volumes were determined by bioimpedance analysis. Results: Carotid-femoral pulse wave velocity (9.30 ± 3.30 vs 7.59 ± 2.66 m/s, p < 0.001), augmentation index (24.52 ± 9.42 vs 20.28 ± 10.19, p < 0.001), and aortic pulse pressure (38 ± 14 vs 29 ± 8 mmHg, p < 0.001) significantly decreased after hemodialysis. Pre-dialysis carotid-femoral pulse wave velocity was associated with age (r2 = 0.15, p = 0.01), total cholesterol (r2 = 0.06, p = 0.02), peripheral mean blood pressure (r2 = 0.10, p = 0.005), aortic-mean blood pressure (r2 = 0.06, p = 0.02), aortic pulse pressure (r2 = 0.14, p = 0.001), and extracellular fluid/total body fluid (r2 = 0.30, p < 0.0001). Pre-dialysis augmentation index was associated with total cholesterol (r2 = 0.06, p = 0,02), aortic-mean blood pressure (r2 = 0.16, p < 0.001), and aortic pulse pressure (r2 = 0.22, p < 0.001). Δcarotid-femoral pulse wave velocity was associated with Δaortic-mean blood pressure (r2 = 0.06, p = 0.02) and inversely correlated with baseline carotid-femoral pulse wave velocity (r2 = 0.29, p < 0.001). Pre-dialysis Δaugmentation index was significantly associated with Δaortic-mean blood pressure (r2 = 0.09, p = 0.009) and Δaortic pulse pressure (r2 = 0.06, p = 0.03) and inversely associated with baseline augmentation index (r2 = 0.14, p = 0.001). In multiple linear regression analysis (adjusted R2 = 0.46, p < 0.001) to determine the factors predicting Log carotid-femoral pulse wave velocity, extracellular fluid/total body fluid and peripheral mean blood pressure significantly predicted Log carotid-femoral pulse wave velocity (p = 0.001 and p = 0.006, respectively). Conclusion: Carotid-femoral pulse wave velocity, augmentation index, and aortic pulse pressure significantly decreased after hemodialysis. Arterial stiffness was associated with both peripheral and aortic blood pressure. Furthermore, reduction in arterial stiffness parameters was related to reduction in aortic blood pressure. Pre-dialysis carotid-femoral pulse wave velocity was associated with volume status determined by bioimpedance analysis. Volume control may improve not only the aortic blood pressure measurements but also arterial stiffness in hemodialysis patients.

scholarly journals Differential Effects of Combination of Renin-Angiotensin-Aldosterone System Inhibitors on Central Aortic Blood Pressure: A Cross-Sectional Observational Study in Hypertensive Outpatients

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Akshyaya Pradhan ◽  
Pravesh Vishwakarma ◽  
Monika Bhandari ◽  
Rishi Sethi ◽  
Varun Shankar Narain
Keyword(s):  
Blood Pressure ◽  
Arterial Stiffness ◽  
Central Hemodynamics ◽  
Cross Sectional ◽  
Treatment Regimens ◽  
Aortic Blood ◽  
Vascular Age ◽  
Aortic Blood Pressure ◽  
The Mean ◽  
Central Aortic Blood Pressure

Background. Central aortic blood pressure (CABP) indices, central hemodynamics, and arterial stiffness are better predictors of cardiovascular events as compared with brachial cuff pressure measurements alone. The present study is aimed at assessing the effects of different antihypertensive drug combination regimens involving renin-angiotensin-aldosterone system (RAAS) inhibitors on CABP indices in Indian patients with hypertension. Methods. This was a cross-sectional, single-center study conducted in patients treated for hypertension for >6 weeks using different treatment regimens involving the combination of RAAS inhibitors with drugs from other classes. CABP indices, vascular age, arterial stiffness, and central hemodynamics were measured in patients using the noninvasive Agedio B900 device (IEM, Stolberg, Germany) and compared between different treatment regimens. Results. A total of 199 patients with a mean age of 54.22±10.15 years were enrolled, where 68.8% had hypertension for over three years and 50.25% had their systolic blood pressure SBP<140 mmHg. Combination treatment with angiotensin II receptor blockers (ARBs) and angiotensin-converting enzyme inhibitors (ACEIs) was given to 77.9% and to 20.1% patients, respectively. The mean vascular age was higher than the actual age (58.13±12.43 vs. 54.22±10.15, p=0.001). The SBP and diastolic blood pressure (DBP) levels in patients treated with ACEI-based combinations were lower than those in patients treated with ARB-based combinations (p<0.05). The mean central pulse pressure amplification, augmentation pressure, and augmentation index were lower in patients treated with ACEI-based combinations than those treated with other treatments (p=0.001). In a subgroup analysis, patients given perindopril and calcium channel blockers (CCBs) or diuretics had significantly lower CABP and pulse wave velocity than those given other treatments (p<0.05). A total of 6.5% patients experienced any side effects. Conclusion. The majority of central hemodynamic parameters, including vascular age, were found to improve more effectively in patients treated with ACEIs than with ARBs. Our results indicate a gap between routine clinical practice and evidence-based guidelines in Indian settings and identify a need to reevaluate the current antihypertensive prescription strategy.

Differential impact of belatacept and cyclosporine A on central aortic blood pressure and arterial stiffness after renal transplantation

2014 ◽  
Vol 28 (9) ◽  
pp. 1004-1009 ◽  
Author(s):  
Felix S. Seibert ◽  
Julia Steltzer ◽  
Eduardo Melilli ◽  
Gerrit Grannas ◽  
Nikolaos Pagonas ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Renal Transplantation ◽  
Arterial Stiffness ◽  
Cyclosporine A ◽  
Differential Impact ◽  
Aortic Blood ◽  
Aortic Blood Pressure ◽  
Central Aortic Blood Pressure

scholarly journals The central aortic blood pressure and arterial stiffness during the daily monitoring procedure in postmenopausal women with osteoporosis

2017 ◽  
Vol 20 (2) ◽  
pp. 46-51
Author(s):  
Svetlana Yu. Tsarenok ◽  
Vladimir V. Gorbunov ◽  
Tatiana A. Aksenova
Keyword(s):  
Blood Pressure ◽  
Arterial Stiffness ◽  
Postmenopausal Women ◽  
Osteoporotic Fractures ◽  
Aortic Pressure ◽  
Daily Monitoring ◽  
Aortic Blood ◽  
Monitoring Procedure ◽  
Aortic Blood Pressure ◽  
Central Aortic Blood Pressure

Aim: to evaluate the data of the central aortic pressure and arterial stiffness during the daily monitoring procedure in postmenopausal women with osteoporosis. Methods: 79 postmenopausal women (age from 57 to 78) were examined. All patients were divided into two groups: the first group consisted of 36 women with osteoporosis, the second group consisted of 43 women – control group. A daily monitoring of central aortic pressure and arterial stiffness were performed all women by the apparatus BPLab v.3.2. Results: increase of the mean daily of systolic, diastolic and mean aortic pressure was found out in women with osteoporosis. The main data of arterial stiffness (PWV, ASI, AASI, PPA) were higher in this group of women. The direct correlation between the data of central aortic blood pressure, arterial stiffness and presence of osteoporotic fractures and their number, as well as indicators of absolute ten-year risk of osteoporotic fractures and hip fracture was revealed. Pathological profiles of systolic pressure in aortae were more frequent in patients with osteoporosis. The type of hyperdispers was predominant. Conclusions: the results obtained may indicate a possible relationship between cardiovascular diseases and osteoporosis.

scholarly journals Central Aortic Blood Pressure and Pulse Wave Velocity as Tools in the Hemodynamic Assessment of Hypertension

2020 ◽  
Vol 6 (3) ◽  
pp. 147-154
Author(s):  
Isabella Tan ◽  
Mark Butlin ◽  
Fatemeh Shirbani ◽  
James R. Cox ◽  
Karen Peebles ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Pulse Wave ◽  
Aortic Blood ◽  
Hemodynamic Assessment ◽  
Aortic Blood Pressure ◽  
Central Aortic Blood Pressure
Sign in / Sign up

Export Citation Format

Share Document