scholarly journals Computational models of liver fibrosis progression for hepatitis C virus chronic infection

2014 ◽  
Vol 15 (S8) ◽  
Author(s):  
James Lara ◽  
F Xavier López-Labrador ◽  
Fernando González-Candelas ◽  
Marina Berenguer ◽  
Yury E Khudyakov
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Liver Fibrosis ◽  
Chronic Infection ◽  
Computational Models ◽  
Fibrosis Progression

scholarly journals Liver Fibrosis Progression and Mortality in Hepatitis B– and C–Coinfected Persons Treated With Directly Acting Antiviral Agents: Results From ERCHIVES

2019 ◽  
Vol 71 (3) ◽  
pp. 664-666 ◽  
Author(s):  
Adeel A Butt ◽  
Peng Yan ◽  
Samia Aslam ◽  
Abdul-Badi Abou-Samra ◽  
Kenneth E Sherman ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Hepatitis B Virus ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Confidence Intervals ◽  
Antiviral Agents ◽  
Virologic Response ◽  
Fibrosis Progression ◽  
B Virus

Abstract For persons with baseline Fibrosis-4 1.46–3.25, cirrhosis incidence/1000 patient-years was 49.3 among hepatitis B virus (HBV)/hepatitis C virus (HCV) coinfected and 18.2 among HCV monoinfected (P = .03). Cirrhosis risk was numerically higher but statistically nonsignificant among HBV/HCV coinfected (hazards ratio [HR] 1.51; 95% confidence intervals [CI], .37–6.05) but lower among those who attained sustained virologic response (HR, .52; 95% CI, .42–.63).

P.366 Simple blood tests as non-invasive markers of liver fibrosis in hemodialysis patients with hepatitis C virus (HCV) chronic infection

2006 ◽  
Vol 36 ◽  
pp. S173
Author(s):  
L.L. Schiavon ◽  
J.L. Narciso ◽  
R.J. Carvalho Filho ◽  
J.P. Sampaio ◽  
V.P. Lanzoni ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Liver Fibrosis ◽  
Chronic Infection ◽  
Hemodialysis Patients ◽  
Non Invasive ◽  
Blood Tests

scholarly journals The Role of Serum Biomarkers in Predicting Fibrosis Progression in Pediatric and Adult Hepatitis C Virus Chronic Infection

PLoS ONE ◽  
2011 ◽  
Vol 6 (8) ◽  
pp. e23218 ◽  
Author(s):  
Pamela Valva ◽  
Paola Casciato ◽  
Juan M. Diaz Carrasco ◽  
Adrian Gadano ◽  
Omar Galdame ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Chronic Infection ◽  
Serum Biomarkers ◽  
Fibrosis Progression

scholarly journals HIV virological rebounds but not blips predict liver fibrosis progression in antiretroviral‐treated HIV /hepatitis C virus‐coinfected patients

HIV Medicine ◽  
2014 ◽  
Vol 16 (1) ◽  
pp. 24-31 ◽  
Author(s):  
C Cooper ◽  
KC Rollet‐Kurhajec ◽  
J Young ◽  
C Vasquez ◽  
M Tyndall ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Liver Fibrosis ◽  
Fibrosis Progression

scholarly journals Liver fibrosis progression in HIV/hepatitis C virus coinfected patients with normal aminotransferases levels

2012 ◽  
Vol 45 (4) ◽  
pp. 444-447 ◽  
Author(s):  
Fábio Heleno de Lima Pace ◽  
Lincoln Eduardo Vieira de Castro Ferreira ◽  
Antonio Eduardo Benedito Silva ◽  
Maria Lucia Gomes Ferraz
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Liver Fibrosis ◽  
Liver Biopsy ◽  
Hepatitis B Surface Antigen ◽  
Hcv Rna ◽  
Progression Rate ◽  
Fibrosis Progression ◽  
Normal Alanine Aminotransferase ◽  
Normal Alt

INTRODUCTION: Approximately 30% of hepatitis C virus (HCV) monoinfected patients present persistently normal alanine aminotransferase (ALT) levels. Most of these patients have a slow progression of liver fibrosis. Studies have demonstrated the rate of liver fibrosis progression in hepatitis C virus-human immunodeficiency virus (HCV-HIV) coinfected patients is faster than in patients infected only by HCV. Few studies have evaluated the histological features of chronic hepatitis C in HIV-infected patients with normal ALT levels. METHODS: HCV-HIV coinfected patients (HCV-RNA and anti-HIV positive) with known time of HCV infection (intravenous drugs users) were selected. Patients with hepatitis B surface antigen (HBsAg) positive or hepatitis C treatment before liver biopsy were excluded. Patients were considered to have a normal ALT levels if they had at least 3 normal determinations in the previous 6 months prior to liver biopsy. All patients were submitted to liver biopsy and METAVIR scale was used. RESULTS: Of 50 studied patients 40 (80%) were males. All patients were treated with antiretroviral therapy. The ALT levels were normal in 13 (26%) patients. HCV-HIV co-infected patients with normal ALT levels had presented means of the liver fibrosis stages (0.77±0.44 versus 1.86±1.38; p<0.001) periportal inflammatory activity (0.62±0.77 versus 2.24±1.35; p<0.001) and liver fibrosis progression rate (0.058±0.043 fibrosis unit/year versus 0.118±0.102 fibrosis unit/year) significantly lower as compared to those with elevated ALT. CONCLUSIONS: HCV-HIV coinfected patients with persistently normal ALTs showed slower progression of liver fibrosis. In these patients the development of liver cirrhosis is improbable.

scholarly journals Longitudinal Analysis of Hepatitis C Virus Replication and Liver Fibrosis Progression in Renal Transplant Recipients

2000 ◽  
Vol 181 (3) ◽  
pp. 852-858 ◽  
Author(s):  
Jacques Izopet ◽  
Lionel Rostaing ◽  
Karine Sandres ◽  
Jean‐Marc Cisterne ◽  
Christophe Pasquier ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Renal Transplant ◽  
Liver Fibrosis ◽  
Virus Replication ◽  
Longitudinal Analysis ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Fibrosis Progression
Sign in / Sign up

Export Citation Format

Share Document