Development of a novel monoclonal antibody with reactivity to a wide range of Venezuelan equine encephalitis virus strains

Lyn M O'Brien; Cindy D Underwood-Fowler; Sarah A Goodchild; Amanda L Phelps; Robert J Phillpotts

doi:10.1186/1743-422x-6-206

Development of a novel monoclonal antibody with reactivity to a wide range of Venezuelan equine encephalitis virus strains

Virology Journal ◽

10.1186/1743-422x-6-206 ◽

2009 ◽

Vol 6 (1) ◽

Cited By ~ 7

Author(s):

Lyn M O'Brien ◽

Cindy D Underwood-Fowler ◽

Sarah A Goodchild ◽

Amanda L Phelps ◽

Robert J Phillpotts

Keyword(s):

Monoclonal Antibody ◽

Venezuelan Equine Encephalitis Virus ◽

Encephalitis Virus ◽

Venezuelan Equine Encephalitis ◽

Equine Encephalitis Virus ◽

Wide Range ◽

Virus Strains

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Venezuelan equine encephalitis virus complex-specific monoclonal antibody provides broad protection, in murine models, against airborne challenge with viruses from serogroups I, II and III

Virus Research ◽

10.1016/j.virusres.2006.02.003 ◽

2006 ◽

Vol 120 (1-2) ◽

pp. 107-112 ◽

Cited By ~ 25

Author(s):

R.J. Phillpotts

Keyword(s):

Monoclonal Antibody ◽

Venezuelan Equine Encephalitis Virus ◽

Encephalitis Virus ◽

Murine Models ◽

Specific Monoclonal Antibody ◽

Venezuelan Equine Encephalitis ◽

Equine Encephalitis Virus ◽

Virus Complex

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Humanization and mammalian expression of a murine monoclonal antibody against Venezuelan equine encephalitis virus

Vaccine ◽

10.1016/j.vaccine.2007.01.034 ◽

2007 ◽

Vol 25 (16) ◽

pp. 3210-3214 ◽

Cited By ~ 18

Author(s):

Wei-Gang Hu ◽

Damon Chau ◽

Josh Wu ◽

Scott Jager ◽

Les P. Nagata

Keyword(s):

Monoclonal Antibody ◽

Venezuelan Equine Encephalitis Virus ◽

Encephalitis Virus ◽

Murine Monoclonal Antibody ◽

Venezuelan Equine Encephalitis ◽

Equine Encephalitis Virus ◽

Mammalian Expression

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A recombinant humanized monoclonal antibody completely protects mice against lethal challenge with Venezuelan equine encephalitis virus

Vaccine ◽

10.1016/j.vaccine.2010.06.038 ◽

2010 ◽

Vol 28 (34) ◽

pp. 5558-5564 ◽

Cited By ~ 16

Author(s):

Wei-Gang Hu ◽

Amanda L. Phelps ◽

Scott Jager ◽

Damon Chau ◽

Charles C. Hu ◽

...

Keyword(s):

Monoclonal Antibody ◽

Venezuelan Equine Encephalitis Virus ◽

Encephalitis Virus ◽

Venezuelan Equine Encephalitis ◽

Lethal Challenge ◽

Equine Encephalitis Virus ◽

Humanized Monoclonal Antibody

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A recombinant humanized monoclonal antibody to Venezuelan equine encephalitis virus E2 that neutralizes virus in vitro and is effective prophylactically in vivo

Journal of Biotechnology ◽

10.1016/j.jbiotec.2008.07.416 ◽

2008 ◽

Vol 136 ◽

pp. S198

Author(s):

Wei-Gang Hu ◽

Amanda Phelps ◽

Scott Jager ◽

Damon Chau ◽

Wendy Butcher ◽

...

Keyword(s):

Monoclonal Antibody ◽

Venezuelan Equine Encephalitis Virus ◽

Encephalitis Virus ◽

Venezuelan Equine Encephalitis ◽

Equine Encephalitis Virus ◽

Humanized Monoclonal Antibody

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Genetic Variation of Venezuelan Equine Encephalitis Virus Strains of the ID Variety in Colombia

American Journal of Tropical Medicine and Hygiene ◽

10.4269/ajtmh.1988.38.195 ◽

1988 ◽

Vol 38 (1) ◽

pp. 195-204 ◽

Cited By ~ 23

Author(s):

Rebeca Rico-Hesse ◽

John T. Roehrig ◽

Robert W. Dickerman ◽

Dennis W. Trent

Keyword(s):

Genetic Variation ◽

Venezuelan Equine Encephalitis Virus ◽

Encephalitis Virus ◽

Venezuelan Equine Encephalitis ◽

Equine Encephalitis Virus ◽

Virus Strains

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A humanised murine monoclonal antibody with broad serogroup specificity protects mice from challenge with Venezuelan equine encephalitis virus

Antiviral Research ◽

10.1016/j.antiviral.2011.01.010 ◽

2011 ◽

Vol 90 (1) ◽

pp. 1-8 ◽

Cited By ~ 10

Author(s):

Sarah A. Goodchild ◽

Lyn M. O’Brien ◽

John Steven ◽

Mischa R. Muller ◽

Oliver J. Lanning ◽

...

Keyword(s):

Monoclonal Antibody ◽

Venezuelan Equine Encephalitis Virus ◽

Encephalitis Virus ◽

Murine Monoclonal Antibody ◽

Venezuelan Equine Encephalitis ◽

Equine Encephalitis Virus

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A humanised murine monoclonal antibody protects mice from Venezuelan equine encephalitis virus, Everglades virus and Mucambo virus when administered up to 48h after airborne challenge

Virology ◽

10.1016/j.virol.2012.01.038 ◽

2012 ◽

Vol 426 (2) ◽

pp. 100-105 ◽

Cited By ~ 13

Author(s):

Lyn M. O'Brien ◽

Sarah A. Goodchild ◽

Robert J. Phillpotts ◽

Stuart D. Perkins

Keyword(s):

Monoclonal Antibody ◽

Venezuelan Equine Encephalitis Virus ◽

Encephalitis Virus ◽

Murine Monoclonal Antibody ◽

Venezuelan Equine Encephalitis ◽

Equine Encephalitis Virus

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Treatment of mice with human monoclonal antibody 24h after lethal aerosol challenge with virulent Venezuelan equine encephalitis virus prevents disease but not infection

Virology ◽

10.1016/j.virol.2011.03.016 ◽

2011 ◽

Vol 414 (2) ◽

pp. 146-152 ◽

Cited By ~ 21

Author(s):

Ann R. Hunt ◽

Richard A. Bowen ◽

Shana Frederickson ◽

Toshiaki Maruyama ◽

John T. Roehrig ◽

...

Keyword(s):

Monoclonal Antibody ◽

Human Monoclonal Antibody ◽

Venezuelan Equine Encephalitis Virus ◽

Encephalitis Virus ◽

Venezuelan Equine Encephalitis ◽

Equine Encephalitis Virus

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Exposing cryptic epitopes on the Venezuelan equine encephalitis virus E1 glycoprotein prior to treatment with alphavirus cross-reactive monoclonal antibody allows blockage of replication early in infection

Virology ◽

10.1016/j.virol.2021.09.007 ◽

2021 ◽

Author(s):

Amanda E. Calvert ◽

Susan L. Bennett ◽

Ann R. Hunt ◽

Rachel H. Fong ◽

Benjamin J. Doranz ◽

...

Keyword(s):

Monoclonal Antibody ◽

Venezuelan Equine Encephalitis Virus ◽

Encephalitis Virus ◽

Venezuelan Equine Encephalitis ◽

Equine Encephalitis Virus ◽

Cryptic Epitopes

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Complete Coding Sequences of Eastern Equine Encephalitis Virus and Venezuelan Equine Encephalitis Virus Strains Isolated from Human Cases

Genome Announcements ◽

10.1128/genomea.00243-15 ◽

2015 ◽

Vol 3 (2) ◽

Cited By ~ 5

Author(s):

Guo-Yun Yu ◽

Michael R. Wiley ◽

Jeffrey R. Kugelman ◽

Jason T. Ladner ◽

Brett F. Beitzel ◽

...

Keyword(s):

Venezuelan Equine Encephalitis Virus ◽

Encephalitis Virus ◽

Venezuelan Equine Encephalitis ◽

Eastern Equine Encephalitis Virus ◽

Coding Sequences ◽

Eastern Equine Encephalitis ◽

Equine Encephalitis Virus ◽

Virus Strains

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