scholarly journals Neoadjuvant chemoradiation with Gemcitabine for locally advanced pancreatic cancer

2012 ◽  
Vol 7 (1) ◽  
Author(s):  
Daniel Habermehl ◽  
Kerstin Kessel ◽  
Thomas Welzel ◽  
Holger Hof ◽  
Amir Abdollahi ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Locally Advanced ◽  
Advanced Pancreatic Cancer ◽  
Neoadjuvant Chemoradiation ◽  
Locally Advanced Pancreatic Cancer

Prognostic Impact of CA 19-9 on Outcome after Neoadjuvant Chemoradiation in Patients with Locally Advanced Pancreatic Cancer

2014 ◽  
Vol 21 (8) ◽  
pp. 2801-2807 ◽  
Author(s):  
Stephanie E. Combs ◽  
Daniel Habermehl ◽  
Kerstin A. Kessel ◽  
Frank Bergmann ◽  
Jens Werner ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Locally Advanced ◽  
Advanced Pancreatic Cancer ◽  
Neoadjuvant Chemoradiation ◽  
Locally Advanced Pancreatic Cancer ◽  
Prognostic Impact

Pancreaticoduodenectomy after Neoadjuvant Therapy in a Jehovah's Witness with Locally Advanced Pancreatic Cancer: Case Report and Approach to Avoid Transfusion

2006 ◽  
Vol 72 (5) ◽  
pp. 435-437 ◽  
Author(s):  
David Magner ◽  
James R. Ouellette ◽  
Joseph R. Lee ◽  
Steven Colquhoun ◽  
Simon Lo ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Relevant Literature ◽  
Locally Advanced ◽  
Advanced Pancreatic Cancer ◽  
Neoadjuvant Chemoradiation ◽  
Locally Advanced Pancreatic Cancer ◽  
Major Surgery ◽  
Cancer Case ◽  
Jehovah’S Witness ◽  
Jehovah's Witness

Although the morbidity and mortality rates associated with pancreaticoduodenectomy (PD) have been improving over the past several decades, perioperative transfusions are often needed. Here, we review the preoperative planning and overall management of a Jehovah's Witness patient with locally advanced pancreatic cancer who would not accept blood transfusion. Management of this case is reviewed, along with the relevant literature regarding major surgery in the Jehovah's Witness population. The use of neoadjuvant chemoradiation was used successfully in locally advanced disease, allowing surgical resection. In addition, we outline a cogent strategy using pre-, intra-, and postoperative techniques to minimize blood loss and maintain hemoglobin at acceptable levels thereby preventing the need for transfusion. These strategies, once in place, may be able to reduce transfusions in all patients having major resections for malignancy.

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