A phase 1, partially blind, placebo-controlled, ascending single and multiple oral dose, safety, tolerability, pharmacokinetic and pharmacodynamic study in healthy subjects and osteoarthritis patients administered APPA-1

http://isrctn.com/ ◽

10.1186/isrctn13784998 ◽

2018 ◽

Author(s):

Matthew Bickerstaff

Keyword(s):

Oral Dose ◽

Healthy Subjects ◽

Phase 1 ◽

Multiple Oral Dose ◽

Pharmacodynamic Study

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The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASP3652 in First-in-Human and Ascending Multiple Oral Dose Studies in Healthy Subjects

Advances in Therapy ◽

10.1007/s12325-020-01402-1 ◽

2020 ◽

Vol 37 (9) ◽

pp. 3878-3900

Author(s):

Masaomi Takizawa ◽

Dirk Cerneus ◽

Ingrid Michon ◽

Sanne Rijnders ◽

Desiree van der Heide ◽

...

Keyword(s):

Oral Dose ◽

Healthy Subjects ◽

Pharmacokinetics And Pharmacodynamics ◽

Multiple Oral Dose

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PII-34PRX-00023, a novel 5HT1A agonist discovered in-silico is safe and well tolerated following multiple oral dose administration in healthy subjects

Clinical Pharmacology & Therapeutics ◽

10.1016/j.clpt.2005.12.159 ◽

2006 ◽

Vol 79 (2) ◽

pp. P45-P45

Author(s):

G IYER ◽

S OSHANA ◽

S DONAHUE

Keyword(s):

Oral Dose ◽

In Silico ◽

Healthy Subjects ◽

Dose Administration ◽

Multiple Oral Dose ◽

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A phase 1, randomized, double-blind, placebo-controlled dose-escalating, safety, tolerability, pharmacokinetic, and pharmacodynamic study of oral recombinant human interleukin eleven (O-rhIl-11) in normal healthy subjects

Gastroenterology ◽

10.1016/s0016-5085(03)81907-8 ◽

2003 ◽

Vol 124 (4) ◽

pp. A377 ◽

Author(s):

Monette M. Cotreau ◽

Lucille Stonis ◽

Ullrich S. Schwertschlag

Keyword(s):

Healthy Subjects ◽

Phase 1 ◽

Double Blind ◽

Double Blind Placebo ◽

Pharmacodynamic Study ◽

Dose Escalating

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Multiple Oral Dose Pharmacokinetic and Pharmacodynamic Study of a Sustained-Release Formulation of Bunazosin (E1015) in Healthy Volunteers

Drug Investigation ◽

10.1007/bf03259235 ◽

1993 ◽

Vol 5 (6) ◽

pp. 302-308

Author(s):

Nobumichi Morishita ◽

Yoshiro Tomono ◽

Jiro Hasegawa ◽

Paul Branagan

Keyword(s):

Oral Dose ◽

Sustained Release ◽

Healthy Volunteers ◽

Release Formulation ◽

Sustained Release Formulation ◽

Multiple Oral Dose ◽

Pharmacodynamic Study

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Safety, Pharmacokinetic, and Pharmacodynamic Study of TS-142 in Healthy Subjects

Case Medical Research ◽

10.31525/ct1-nct04087707 ◽

2019 ◽

Author(s):

Keyword(s):

Healthy Subjects ◽

Pharmacodynamic Study

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Food-effect on PK and PD of Single Oral Dose of HIP1601 in Healthy Subjects

Case Medical Research ◽

10.31525/ct1-nct04204629 ◽

2019 ◽

Author(s):

Keyword(s):

Oral Dose ◽

Single Oral Dose ◽

Healthy Subjects ◽

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A Phase 1 Double-Blinded Study for Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of ATI-2173 in Healthy Subjects and Subjects With Chronic Hepatitis B Virus Infection

Case Medical Research ◽

10.31525/ct1-nct04248426 ◽

2020 ◽

Author(s):

Keyword(s):

Chronic Hepatitis ◽

Hepatitis B Virus ◽

Virus Infection ◽

Healthy Subjects ◽

Phase 1 ◽

Hepatitis B Virus Infection ◽

Chronic Hepatitis B Virus ◽

B Virus ◽

Blinded Study ◽

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Faculty Opinions recommendation of A Phase 1, Single-center, Double-blind, Placebo-controlled Study in Healthy Subjects to Assess the Safety, Tolerability, Clinical Effects, and Pharmacokinetics-Pharmacodynamics of Intravenous Cyclopropyl-methoxycarbonylmetomidate (ABP-700) after a Single Ascending Bolus Dose.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727567304.793536193 ◽

2017 ◽

Author(s):

Harald Ihmsen

Keyword(s):

Healthy Subjects ◽

Phase 1 ◽

Controlled Study ◽

Clinical Effects ◽

Single Center ◽

Double Blind ◽

Double Blind Placebo

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Andrographis paniculata: Dissolution investigation and pharmacokinetic studies of four major active diterpenoids after multiple oral dose administration in healthy Thai volunteers

Journal of Ethnopharmacology ◽

10.1016/j.jep.2016.09.058 ◽

2016 ◽

Vol 194 ◽

pp. 513-521 ◽

Author(s):

Nanthanit Pholphana ◽

Duangchit Panomvana ◽

Nuchanart Rangkadilok ◽

Tawit Suriyo ◽

Porranee Puranajoti ◽

...

Keyword(s):

Oral Dose ◽

Andrographis Paniculata ◽

Pharmacokinetic Studies ◽

Dose Administration ◽

Multiple Oral Dose

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Single and multiple dose pharmacokinetics and safety of ZSP1273, an RNA polymerase PB2 protein inhibitor of the influenza A virus: A Phase 1 double-blind study in healthy subjects

Expert Opinion on Investigational Drugs ◽

10.1080/13543784.2021.1994944 ◽

2021 ◽

Author(s):

Yue Hu ◽

Haijun Li ◽

Min Wu ◽

Hong Zhang ◽

Yanhua Ding ◽

...

Keyword(s):

Rna Polymerase ◽

Influenza A Virus ◽

Healthy Subjects ◽

Influenza A ◽

Multiple Dose ◽

Phase 1 ◽

Double Blind Study ◽

Protein Inhibitor ◽

Double Blind ◽

Multiple Dose Pharmacokinetics

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