Multicentre, randomised, triple-blind, placebo-controlled study to evaluate the clinical efficacy and safety of an oral rehydration solution (Recuperat-ion®) in the treatment of fibromyalgia

2013 ◽  
Author(s):  
Jordi Carbonell
Keyword(s):  
Clinical Efficacy ◽  
Oral Rehydration Solution ◽  
Controlled Study ◽  
Efficacy And Safety ◽  
Oral Rehydration ◽  
Rehydration Solution

scholarly journals Efficacy of an Oral Rehydration Solution Enriched with Lactobacillus reuteri DSM 17938 and Zinc in the Management of Acute Diarrhoea in Infants: A Randomized, Double-Blind, Placebo-Controlled Trial

Nutrients ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1189 ◽  
Author(s):  
Maria Maragkoudaki ◽  
George Chouliaras ◽  
Antonia Moutafi ◽  
Athanasios Thomas ◽  
Archodoula Orfanakou ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Lactobacillus Reuteri ◽  
Oral Rehydration Solution ◽  
Statistical Significance ◽  
Acute Diarrhoea ◽  
Controlled Study ◽  
Double Blind ◽  
Oral Rehydration ◽  
Number Of Patients ◽  
Rehydration Solution

The efficacy of oral rehydration solution (ORS) enriched with Lactobacillus reuteri DSM 17938 and zinc in infants with acute gastroenteritis, is poorly defined. The aim of this double-blind, randomized, placebo-controlled study, was to assess the efficacy of an ORS enriched with Lactobacillus reuteri DSM 17938 and zinc (ORS+Lr&Z) in well-nourished, non-hospitalized infants with acute diarrhoea. Fifty one infants with acute diarrhoea were randomly assigned to receive either ORS+Lr&Z (28 infants, mean ± SD age 1.7 ± 0.7 years, 21 males), or standard ORS (ORS−Lr&Z; 23 infants, mean ± SD age 1.8 ± 0.7 years, 16 males). Stools volume and consistency were recorded pre- and posttreatment using the Amsterdam Infant Stool Scale and were compared between the two groups, as well as lost work/day care days, drug administration and need for hospitalization. Both groups showed reduction in the severity of diarrhoea on day two (p < 0.001) while, all outcomes showed a trend to be better in the ORS+Lr&Z group, without reaching statistical significance, probably due to the relatively small number of patients. No adverse effects were recorded. In conclusion, both ORS were effective in managing acute diarrhoea in well-nourished, non-hospitalized infants. ORS enriched with L. reuteri DSM 17938 and zinc was well tolerated with no adverse effects.

Are oral rehydration solutions optimized for treating diarrhea?

2021 ◽  
pp. 026010602199164
Author(s):  
Samuel N Cheuvront ◽  
Robert W Kenefick ◽  
Laura Luque ◽  
Katherine M Mitchell ◽  
Sadasivan Vidyasagar
Keyword(s):  
Water Absorption ◽  
Intestinal Absorption ◽  
Turning Point ◽  
Oral Rehydration Solution ◽  
Salt Water ◽  
Food Science ◽  
Oral Rehydration ◽  
Rehydration Solutions ◽  
Rehydration Solution ◽  
Stool Volume

Background: A historical turning point occurred in the treatment of diarrhea when it was discovered that glucose could enhance intestinal sodium and water absorption. Adding glucose to salt water (oral rehydration solution, ORS) more efficiently replaced intestinal water and salt losses. Aim: Provide a novel hypothesis to explain why mainstream use of ORS has been strongly recommended, but weakly adopted. Methods: Traditional (absorptive) and novel (secretory) physiological functions of glucose in an ORS were reviewed. Results: Small amounts of glucose can stimulate both intestinal absorption and secretion. Glucose can exacerbate a net secretory state and may aggravate pathogen-induced diarrhea, particularly for pathogens that affect glucose transport. Conclusion: A hypothesis is made to explain why glucose-based ORS does not appreciably reduce diarrheal stool volume and why modern food science initiatives should focus on ORS formulations that replace water and electrolytes while also reducing stool volume and duration of diarrhea.

Oral Rehydration Solution Therapy in the Management of Children with Rotavirus Diarrhea

2009 ◽  
Vol 58 (3) ◽  
pp. 80-87 ◽  
Author(s):  
Germain Nappert ◽  
Jose Miguel Barrios ◽  
Gordon A. Zello ◽  
Jonathan M. Naylor
Keyword(s):  
Oral Rehydration Solution ◽  
Oral Rehydration ◽  
Rehydration Solution ◽  
Rotavirus Diarrhea

scholarly journals 78. TOWARD A SUPER-ORAL REHYDRATION SOLUTION (ORS): ENHANCEMENT OF INTESTINAL WATER ABSORPTION BY A POLY-NUTRIENT SOLUTION

1987 ◽  
Vol 22 (1) ◽  
pp. 109-109
Author(s):  
A Nocerlno ◽  
M Migliavacca ◽  
A Fasano ◽  
C Verqa ◽  
A Ferrara ◽  
...  
Keyword(s):  
Water Absorption ◽  
Nutrient Solution ◽  
Oral Rehydration Solution ◽  
Oral Rehydration ◽  
Rehydration Solution
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