scholarly journals Cerebellar venous thrombosis mimicking a cerebellar tumor due to polycythemia vera: a case report

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hongfeng Wen ◽  
Di Jin ◽  
Yu Chen ◽  
Bin Cui ◽  
Tianyi Xiao
Keyword(s):  
Venous Thrombosis ◽  
Polycythemia Vera ◽  
Delayed Diagnosis ◽  
Janus Kinase ◽  
Cerebellar Hemisphere ◽  
Cerebellar Tumor ◽  
Cortical Vein ◽  
Vein Thrombosis ◽  
Cortical Vein Thrombosis ◽  
V617f Mutation

Abstract Background Cerebral venous thrombosis (CVT) occurs rarely in the general population and is frequently associated with confused clinical findings and delayed diagnosis. Isolated cerebellar cortical vein thrombosis is a very rare phenomenon. Case presentation This report describes a case with CVT, which is manifested as space-occupying lesions of the cerebellar hemisphere and mimics a cerebellar tumor at the beginning. The diagnosis of CVT was finalized given the laboratory and brain biopsy findings. The etiology may be related to polycythemia vera with Janus Kinase 2 V617F mutation. Conclusion Isolated cerebellar vein thrombosis should be considered when swelling and enhancing cerebellar lesions are detected. Polycythemia vera, especially with a positive JAK2 V617F mutation, may be a rare risk factor for CVT.

scholarly journals Cerebellar cortical vein thrombosis mimicking a vermian tumor: case report

2017 ◽  
Vol 31 (3) ◽  
pp. 309-312 ◽  
Author(s):  
Marcelo D Vilela ◽  
Hugo AS Pedrosa ◽  
Marco Antonio D Filho
Keyword(s):  
Case Report ◽  
Sinus Thrombosis ◽  
Cerebellar Hemisphere ◽  
Dural Sinus ◽  
Cerebellar Tumor ◽  
Dural Sinus Thrombosis ◽  
Venous Infarction ◽  
Cortical Vein ◽  
Vein Thrombosis ◽  
Cortical Vein Thrombosis

Cortical vein thrombosis is an uncommon cause of stroke and generally occurs in the supratentorial compartment. Spontaneous venous thrombosis with infarction in the posterior fossa usually occurs in association with either dural sinus thrombosis and/or thrombosis of the petrosal vein, usually with venous infarction of the cerebellar hemisphere. Our goal is to present the case of a patient with thrombosis of cerebellar cortical veins, without sinus involvement, which mimicked a vermian cerebellar tumor.

scholarly journals Acute symptomatic seizures in cerebral venous thrombosis

Neurology ◽  
2020 ◽  
Vol 95 (12) ◽  
pp. e1706-e1715 ◽  
Author(s):  
Erik Lindgren ◽  
Suzanne M. Silvis ◽  
Sini Hiltunen ◽  
Mirjam R. Heldner ◽  
Fabiola Serrano ◽  
...  
Keyword(s):  
Venous Thrombosis ◽  
Cerebral Edema ◽  
Cerebral Venous Thrombosis ◽  
Sinus Thrombosis ◽  
Cortical Vein ◽  
Vein Thrombosis ◽  
Sagittal Sinus ◽  
Cortical Vein Thrombosis ◽  
Symptomatic Seizures ◽  
Acute Symptomatic Seizures

ObjectiveTo identify characteristics, predictors, and outcomes of acute symptomatic seizures (ASS) in cerebral venous thrombosis (CVT), we investigated 1,281 consecutive adult patients with CVT included from 12 hospitals within the International CVT Consortium.MethodsWe defined ASS as any seizure between symptom onset and 7 days after diagnosis of CVT. We stratified ASS into prediagnosis and solely postdiagnosis ASS. Status epilepticus (SE) was also analyzed separately. We analyzed predictors for ASS and the association between ASS and clinical outcome (modified Rankin Scale) with multivariable logistic regression.ResultsOf 1,281 eligible patients, 441 (34%) had ASS. Baseline predictors for ASS were intracerebral hemorrhage (ICH; adjusted odds ratio [aOR] 4.1, 95% confidence interval [CI] 3.0–5.5), cerebral edema/infarction without ICH (aOR 2.8, 95% CI 2.0–4.0), cortical vein thrombosis (aOR 2.1, 95% CI 1.5–2.9), superior sagittal sinus thrombosis (aOR 2.0, 95% CI 1.5–2.6), focal neurologic deficit (aOR 1.9, 95% CI 1.4–2.6), sulcal subarachnoid hemorrhage (aOR 1.6, 95% CI 1.1–2.5), and female-specific risk factors (aOR 1.5, 95% CI 1.1–2.1). Ninety-three (7%) patients had solely postdiagnosis ASS, best predicted by cortical vein thrombosis (positive/negative predictive value 22%/92%). Eighty (6%) patients had SE, independently predicted by ICH, focal neurologic deficits, and cerebral edema/infarction. Neither ASS nor SE was independently associated with outcome.ConclusionASS occurred in one-third of patients with CVT and was associated with brain parenchymal lesions and thrombosis of the superficial system. In the absence of prediagnosis ASS, no subgroup was identified with sufficient risk of postdiagnosis ASS to justify prophylactic antiepileptic drug treatment. We found no association between ASS and outcome.

Multimodal diagnosis of cortical vein thrombosis

2007 ◽  
Vol 34 (S 2) ◽  
Author(s):  
J Linn ◽  
T Pfefferkorn ◽  
S Michl ◽  
M Wiesmann ◽  
S Hartz ◽  
...  
Keyword(s):  
Cortical Vein ◽  
Vein Thrombosis ◽  
Cortical Vein Thrombosis

Isolated cortical vein thrombosis in a patient with sickle cell disease: Treatment with decompressive craniotomy and anticoagulation and literature review

2013 ◽  
Vol 61 (2) ◽  
pp. 173 ◽  
Author(s):  
PedroTadao Hamamoto Filho ◽  
RobertoColichio Gabarra ◽  
GabrielPereira Braga ◽  
LucileneSilva Ruiz e Resende ◽  
Rodrigo Bazan ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Literature Review ◽  
Sickle Cell ◽  
Cell Disease ◽  
Disease Treatment ◽  
Cortical Vein ◽  
Vein Thrombosis ◽  
Decompressive Craniotomy ◽  
Cortical Vein Thrombosis

scholarly journals Malignant isolated cortical vein thrombosis with type II protein S deficiency: a case report

BMC Neurology ◽  
2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Nobuhiko Arai ◽  
Masanao Tabuse ◽  
Akiyoshi Nakamura ◽  
Hiromichi Miyazaki
Keyword(s):  
Case Report ◽  
Protein S ◽  
Type Ii ◽  
Protein S Deficiency ◽  
Cortical Vein ◽  
Vein Thrombosis ◽  
Cortical Vein Thrombosis ◽  
S Deficiency

Maternal Cortical Vein Thrombosis and the Obstetric Anesthesiologist

1987 ◽  
Vol 7 (2) ◽  
pp. 54
Author(s):  
D. Younker ◽  
M. M. Jones ◽  
J. Adenwala ◽  
A. Citrin ◽  
T. H. Joyce
Keyword(s):  
Cortical Vein ◽  
Vein Thrombosis ◽  
Cortical Vein Thrombosis
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