The postoperative patient-reported quality of recovery in colorectal cancer patients under enhanced recovery after surgery using QoR-40

Background: In Malaysia, colorectal cancer is ranked the second most frequent cancer among men and women. Despite that, research on patient-reported outcomes in colorectal cancer is scarce. Aim: This study aimed to determine the pattern and factors affecting health-related quality of life (HRQOL) among colorectal cancer patients treated at the University Malaya Medical Centre (UMMC), Malaysia. Methods: This study is a cross sectional assessment of health-related quality of life of colorectal cancer patients attending UMMC using locally validated Bahasa Malaysia (BM) and Malaysian Chinese versions of the EORTC QLQ-C30 core and colorectal cancer specific EORTC-QLQ-CR29 tools. Data were drawn from patients' records, national registration department and interviews (physical and telephone). Statistical analyses included descriptive, psychometric evaluations and stepwise multiple linear regression models. Results: The reliability and validity of the BM and Malaysian Chinese tools were examined among 189 patients. The questionnaires were acceptable to the patients, with adequate Cronbach's alpha in all but the cognitive function scale, test-retest coefficient were adequate, and all items fulfilled the criteria for convergent and discriminant validity except question number 5 in QLQ-C30 in both the tools. Three hundred and twenty patients not involved in the validation study were surveyed and these patients rated their global health status/quality of life (GHS/QOL) and functional well-being higher than the EORTC reference values and reported fewer symptoms. Ethnicity was associated with the GHS/QOL at univariate level only. Role, social/family functioning scales were the two independent predictors of GHS/QOL and both are modifiable. Conclusion: Proactive engagement of patients to share their experiences with colorectal cancer and its treatment is recommended. Emphasis should be role, social and family functions, which were found to be proxies for the overall GHS/QOL.

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Evaluation on Safety and Efficacy of an Enhanced Recovery After Surgery (ERAS) Protocol to Colorectal Cancer Patients

Nippon Daicho Komonbyo Gakkai Zasshi ◽

10.3862/jcoloproctology.64.214 ◽

2011 ◽

Vol 64 (4) ◽

pp. 214-223 ◽

Cited By ~ 1

Author(s):

Hirofumi Ota ◽

Yujiro Fujie ◽

Hiroki Fukunaga ◽

Takayuki Ogino ◽

Yoshiichi Maeura

Keyword(s):

Colorectal Cancer ◽

Cancer Patients ◽

Enhanced Recovery ◽

Enhanced Recovery After Surgery ◽

Safety And Efficacy ◽

Colorectal Cancer Patients ◽

Eras Protocol

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Safety and Quality of Life in the Treatment of Non-metastasic Colorectal Cancer Patients: 5-fluorouracil Versus Capecitabine

10.28991/iccr-2019-006 ◽

2019 ◽

Author(s):

Julia Sánchez-Gundín ◽

Cristina Martín-Sabroso ◽

Ana M. Fernández-Carballido ◽

D. Barreda-Hernández ◽

Ana I. Torres-Suárez

Keyword(s):

Quality Of Life ◽

Colorectal Cancer ◽

Cancer Patients ◽

Colorectal Cancer Patients

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472 Addressing the Quality of Hospital Care of Colorectal Cancer Patients Undergoing Surgery: What Did We Learn from the National Bowel Cancer Audit?

British Journal of Surgery ◽

10.1093/bjs/znab134.558 ◽

2021 ◽

Vol 108 (Supplement_2) ◽

Author(s):

C Li ◽

S Z Y Ooi ◽

T Woo ◽

P H M Chan

Keyword(s):

Colorectal Cancer ◽

Cancer Patients ◽

External Validation ◽

Distant Metastases ◽

Management Plan ◽

Bowel Cancer ◽

Clinical Factors ◽

Quality Outcomes ◽

Colorectal Cancer Patients

Abstract Aim To identify the most relevant clinical factors in the National Bowel Cancer Audit (NBOCA) that contribute to the variation in the quality of care provided in different hospitals for colorectal cancer patients undergoing surgery. Method Data from 36,116 patients with colorectal cancer who had undergone surgery were retrospectively collected from the NBOCA and analysed from 145 and 146 hospitals over two years. A validated multiple linear regression was performed to compare the identified clinical factors with various quality outcomes. The quality outcomes defined in this study were the length of hospitalisation, 2-year mortality, readmission rate, 90-day mortality, and 18-month stoma rate. Results Four clinical factors (laparoscopy rate, abdominal-perineal-resection-of-rectum (APER), pre-operative radiotherapy and patients with distant metastases) were shown to have a significant (p < 0.05) impact on the length of hospitalisation and 18-month stoma rate. 18-month stoma rate was also significantly associated with 2-year mortality. External validation of the regression model demonstrated the Root-Mean-Square-Error of 0.811 and 4.62 for 18-month stoma rate and 2-year mortality respectively. Conclusions Hospitals should monitor the four clinical factors for patients with colorectal cancer during perioperative care. Clinicians should consider these factors along with the individual patients’ history when formulating a management plan for patients with colorectal cancer.

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