scholarly journals A cross-sectional study on caregivers’ perspective of the quality of life and adherence of paediatric HIV patients to highly active antiretroviral therapy

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Michael Lahai ◽  
Peter Bai James ◽  
Noel Nen’man Wannang ◽  
Haja Ramatulai Wurie ◽  
Sorie Conteh ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Hiv Patients ◽  
Cross Sectional ◽  
Paediatric Hiv ◽  
Highly Active

scholarly journals A cross-sectional study on caregivers’ perspective of the quality of life and adherence of paediatric HIV patients to highly active antiretroviral therapy

2019 ◽  
Author(s):  
Michael Lahai ◽  
Peter B. James ◽  
Noel N. Wannang ◽  
Haja R. Wurie ◽  
Sorie Conteh ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Nuclear Family ◽  
Hiv Status ◽  
Cross Sectional ◽  
Paediatric Hiv ◽  
Highly Active ◽  
Hiv Aids

Abstract Background Non-compliance to highly active antiretroviral therapy (HAART) can lead to sub-therapeutic drug concentrations in children leading to emergence of drug resistance and poor quality of life in children with HIV/AIDS. This study assess the response of caregivers for determination of the percentage adherence, child and caregivers’ demographics and related characters to the four domains of quality of life in children (aged 14 years and under) on HAART. Methods A cross-sectional survey was done for 188 paediatric patients accompanied by their caregivers’ attending Ola During Children’s Hospital and Makeni Government Hospital between September and November 2016 in Sierra Leone with ethical approval obtained from the Sierra Leone Ethics and Scientific Review Committee; Directorate of Policy and Planning, Ministry of Health and Sanitation. Adherence to HAART was measured as no indication of a missed dose in the past week or month using three adherence questions on dose in the past week or month. Quality of life was assessed using the four domains of the Quality of life summary questionnaire (WHOQOL-BREF) as the dependent variable and the demographic characteristics of caregiver and child as the independent variable. Inferential test was used to determine the association between variables and the regression model to determine association of significant variables to the four domains of the WHOQOL BREF. Results The study showed 5.9% adherence among 188 paediatric HIV/AIDs patients. Caregiver HIV status and caregiver type were also found to be associated with quality of life domains with high mean values for HIV positive caregivers and caregiver type that included a member of the nuclear family (father, mother or siblings). Conclusion This study showed strong association for involvement of caregiver that includes the nuclear family, caregiver’s knowledge of their HIV status and adherence to HAART. Therefore, these factors can improve the quality of life of paediatric HIV/AIDS patients on highly active antiretroviral therapy.

scholarly journals A cross-sectional study on caregivers’ perspective of the quality of life and adherence of paediatric HIV patients to highly active antiretroviral therapy

2020 ◽  
Author(s):  
Michael Lahai ◽  
Peter Bai. James ◽  
Noel N. Wannang ◽  
Haja R. Wurie ◽  
Sorie Conteh ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Nuclear Family ◽  
Cross Sectional Study ◽  
Hiv Status ◽  
Cross Sectional ◽  
Highly Active ◽  
Hiv Aids

Abstract Background Poor compliance to highly active antiretroviral therapy (HAART) can result in poor quality of life in children living with HIV/AIDS because of low plasma drug concentration and the possibility of drug resistance. This study evaluates the response of caregivers for determination of adherence and the four quality of life domains in children (aged 14 years and under) on HAART. Methods Cross-sectional study of 188 children accompanied by their caregivers’ at Ola During Children’s Hospital and Makeni Government Hospital between September and November 2016, with ethical approval obtained from the Sierra Leone Ethics and Scientific Review Committee. Adherence to HAART and Quality of life was assessed using the WHO Quality of life summary questionnaire (WHOQOL-BREF). Results The study revealed 5.9% adherence amongst pediatric patients. Caregiver HIV status and caregiver type was also found to be associated with quality of life domains with high mean values for HIV positive caregivers and caregiver type that includes any member of the nuclear family (father, mother or siblings). Conclusion This study showed strong association for involvement of caregiver that includes the nuclear family, caregiver’s knowledge of their HIV status and adherence to HAART. Therefore, involvement of any member of the nuclear family, HIV positive parents living positively with HIV/AIDS and good adherence to therapy can improve the quality of life of pediatric HIV/AIDS patients on highly active antiretroviral therapy.

scholarly journals A cross-sectional study on caregivers’ perspective of the quality of life and adherence of paediatric HIV patients to Highly Active Antiretroviral Therapy 

2020 ◽  
Author(s):  
Michael Lahai ◽  
Peter Bai. James ◽  
Noel N. Wannang ◽  
Haja R. Wurie ◽  
Sorie Conteh ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Nuclear Family ◽  
Strong Association ◽  
Hiv Positive ◽  
Cross Sectional ◽  
Highly Active ◽  
Health Domains

Abstract Background: Poor compliance to highly active antiretroviral therapy (HAART) can result in the poor quality of life in children living with HIV/AIDS because of low plasma drug concentration and the possibility of drug resistance. This study evaluates the response of caregivers for determination of adherence and the four quality of life domains in children (aged 14 years and under) on HAART.Methods: We conducted a cross-sectional study of 188 children, each accompanied by their caregivers at Ola During Children's Hospital and Makeni Government Hospital between September and November 2016. Adherence to HAART and Quality of life was assessed using the WHO Quality of life summary questionnaire (WHOQOL-BREF). We obtained ethical approval from the Sierra Leone Ethics and Scientific Review Committee. Results: The study revealed 5.9% adherence amongst paediatric patients, and a strong association of adherent patients(p=0.019*) to the physical health domain (mean=64.61 SD=8.1).Caregiver HIV status showed a strong association with the physical (mean=58.3, SD=11.7 and p=0.024*), and psychological health domains (mean=68.2, SD=14.7 and p=0.001). Caregiver type (mother/father/sibling) accompanying child to hospital also showed strong associated with the physical (mean=58.0, SD=10.6, p <0.001), psychological (mean 68.2 SD=14.81 p <0.001) and environmental health domains (mean=59.7, SD=13.47, p <0.001). Further regression analysis showed a strong association with physical health domain for HIV positive caregivers (p=0.014) and adherent paediatric patients (p=0.005). Nuclear family also showed a strong association with psychological (p<0.001) and environmental (p=0.001) health domains. Conclusion: This study showed a strong association between the quality of life domains and the involvement of nuclear family caregiver, HIV-positive caregiver and adherence to HAART. Our study suggests that the involvement of any member of the nuclear family, HIV positive parents and patient adherence to therapy can improve the quality of life of paediatric HIV/AIDS patients on highly active antiretroviral therapy in the two hospitals.

scholarly journals Health-Related Quality of Life in People Living with HIV in Southwest Iran in 2018: A Cross-Sectional Study

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Hassan Joulaei ◽  
Seyed Ghaleb Mousavi ◽  
Zohre Foroozanfar ◽  
Tayebeh Rakhshani
Keyword(s):  
Quality Of Life ◽  
Cross Sectional Study ◽  
Health Related Quality ◽  
Sectional Study ◽  
Hiv Patients ◽  
Cross Sectional ◽  
Related Quality ◽  
Health Related ◽  
The Mean

Health-related quality of life (HRQoL) is one of the most important indicators in assessing the health and well-being of HIV-positive patients. The present study investigated the HRQoL of HIV patients referred to Abadan’s Voluntary Counseling and Testing (VCT) center in 2019. In this cross-sectional study, a total of 134 HIV+ patients referred to Abadan’s VCT center were selected through convenience sampling. Demographic information was collected through a researcher-made checklist; the patients’ status and health information were collected through electronic medical records of HIV+ patients and their records at the VCT center. The HRQoL index was assessed using the World Health Organization (WHOQOL-BREF) questionnaire. Data analysis was carried out using simple and multiple linear regression as well as a t -test in SPSS software. A P value < 0.05 was considered as the significance level in all tests. The mean of the HRQoL in all the participating patients was 56.42 ± 22.66 . The highest and lowest mean scores of HRQoL domains were related to social relationships ( 57.53 ± 24.73 ) and environmental health ( 53.68 ± 19.07 ). There was a positive significant relationship between the marital status, residency, years of education, duration of infection, transmission route, and antiretroviral (ARV) therapy with the score of the HRQoL. The results showed a moderate score for the mean HRQoL and its domains. The present study revealed the necessity of improving HIV+ patients’ living conditions, employment status, health education, and mental health care.

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