Feasibility and long-term safety of Ho:YAG laser lithotripsy in broncholithiasis patients

Abstract Background Treatment of broncholithiasis is complex, especially in the case of a large or transbronchial broncholith. Holmium-yttrium aluminum garnet (Ho:YAG) laser lithotripsy may be a useful treatment in broncholithiasis; however, as it is not yet common practice, the optimal parameters are unknown. Methods We performed a single-center retrospective analysis of the clinical data of 13 broncholithiasis patients who underwent Ho:YAG laser lithotripsy from May 2012 to October 2018. Results For the 13 patients (2 males and 11 females), Ho:YAG laser lithotripsy was performed 17 times, in total. All procedures were performed under general anesthesia with rigid bronchoscopy. We initially set the Ho:YAG laser to a pulse frequency of 5 Hz and a pulse energy of 0.8 J, gradually increasing these as required. The pulse frequency range we employed was 5–15 Hz, and the pulse energy range was 0.8–1.6 J. All broncholiths were successfully extracted after lithotripsy, and all symptoms improved. Hemoptysis, bronchial esophageal fistula, and pneumonia were the most common complications; however, there were no long-term complications. Conclusions Ho:YAG laser lithotripsy is an effective and safe treatment for broncholithiasis, over a long-term follow up.

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Feasibility and long-term safety of Ho:YAG laser lithotripsy in broncholithiasis patients

10.21203/rs.3.rs-38363/v3 ◽

2020 ◽

Author(s):

Yuan Cheng ◽

Guangfa Wang ◽

Wei Zhang ◽

Hong Zhang ◽

Xi Wang

Keyword(s):

Pulse Energy ◽

Yttrium Aluminum Garnet ◽

Pulse Frequency ◽

Laser Lithotripsy ◽

Rigid Bronchoscopy ◽

Ho:Yag Laser ◽

Yttrium Aluminum ◽

Long Term Follow Up

Abstract Background: Treatment of broncholithiasis is complex, especially in the case of a large or transbronchial broncholith. Holmium-yttrium aluminum garnet (Ho:YAG) laser lithotripsy may be a useful treatment in broncholithiasis; however, as it is not yet common practice, the optimal parameters are unknown. Methods: We performed a single-center retrospective analysis of the clinical data of 13 broncholithiasis patients who underwent Ho:YAG laser lithotripsy from May 2012 to October 2018. Results: For the 13 patients (2 males and 11 females), Ho:YAG laser lithotripsy was performed 17 times, in total. All procedures were performed under general anesthesia with rigid bronchoscopy. We initially set the Ho:YAG laser to a pulse frequency of 5 Hz and a pulse energy of 0.8 J, gradually increasing these as required. The pulse frequency range we employed was 5-15 Hz, and the pulse energy range was 0.8-1.6 J. All broncholiths were successfully extracted after lithotripsy, and all symptoms improved. Hemoptysis, bronchial esophageal fistula, and pneumonia were the most common complications; however, there were no long-term complications. Conclusions: Ho:YAG laser lithotripsy is an effective and safe treatment for broncholithiasis, over a long-term follow up.

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Feasibility and Long-Term Safety of Ho:YAG Laser Lithotripsy in Broncholithiasis Patients

10.21203/rs.3.rs-38363/v1 ◽

2020 ◽

Author(s):

Yuan Cheng ◽

Guangfa Wang ◽

Wei Zhang ◽

Hong Zhang ◽

Xi Wang

Keyword(s):

Pulse Energy ◽

Yttrium Aluminum Garnet ◽

Pulse Frequency ◽

Laser Lithotripsy ◽

Rigid Bronchoscopy ◽

Ho:Yag Laser ◽

Yttrium Aluminum ◽

Long Term Follow Up

Abstract Background Treatment of broncholithiasis is complex, especially in the case of a large or transbronchial broncholith. Holmium-yttrium aluminum garnet (Ho:YAG) laser lithotripsy may be a useful treatment in broncholithiasis; however, as it is not yet common practice, the optimal parameters are unknown.Objectives We investigated the feasibility and long-term safety of Ho:YAG lithotripsy in broncholithiasis patients.Method We performed a single-center retrospective analysis of the clinical data of 13 broncholithiasis patients who underwent Ho:YAG laser lithotripsy from May 2012 to October 2018.Result For the 13 patients (2 males and 11 females), Ho:YAG laser lithotripsy was performed 17 times, in total. All procedures were performed under general anesthesia with rigid bronchoscopy. We initially set the Ho:YAG laser to a pulse frequency of 5 Hz and a pulse energy of 0.8 J, gradually increasing these as required. The pulse frequency range we employed was 5-15 Hz, and the pulse energy range was 0.8-1.6 J. All broncholiths were successfully extracted after lithotripsy, and all symptoms improved. Hemoptysis, bronchial esophageal fistula, and pneumonia were the most common complications; however, there were no long-term complications.Conclusions Ho:YAG laser lithotripsy is an effective and safe treatment for broncholithiasis, over a long-term follow up.

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Feasibility and long-term safety of Ho:YAG laser lithotripsy in broncholithiasis patients

10.21203/rs.3.rs-38363/v2 ◽

2020 ◽

Author(s):

Yuan Cheng ◽

Guangfa Wang ◽

Wei Zhang ◽

Hong Zhang ◽

Xi Wang

Keyword(s):

Pulse Energy ◽

Yttrium Aluminum Garnet ◽

Pulse Frequency ◽

Laser Lithotripsy ◽

Rigid Bronchoscopy ◽

Ho:Yag Laser ◽

Yttrium Aluminum ◽

Long Term Follow Up

Abstract BackgroundTreatment of broncholithiasis is complex, especially in the case of a large or transbronchial broncholith. Holmium-yttrium aluminum garnet (Ho:YAG) laser lithotripsy may be a useful treatment in broncholithiasis; however, as it is not yet common practice, the optimal parameters are unknown. MethodsWe performed a single-center retrospective analysis of the clinical data of 13 broncholithiasis patients who underwent Ho:YAG laser lithotripsy from May 2012 to October 2018.ResultsFor the 13 patients (2 males and 11 females), Ho:YAG laser lithotripsy was performed 17 times, in total. All procedures were performed under general anesthesia with rigid bronchoscopy. We initially set the Ho:YAG laser to a pulse frequency of 5 Hz and a pulse energy of 0.8 J, gradually increasing these as required. The pulse frequency range we employed was 5-15 Hz, and the pulse energy range was 0.8-1.6 J. All broncholiths were successfully extracted after lithotripsy, and all symptoms improved. Hemoptysis, bronchial esophageal fistula, and pneumonia were the most common complications; however, there were no long-term complications.ConclusionsHo:YAG laser lithotripsy is an effective and safe treatment for broncholithiasis, over a long-term follow up.

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Minimally Invasive Management of Iatrogenic Ureteral Injuries with Ureteroscope Facilitated by Holmium Yttrium-Aluminum-Garnet Laser

International Scholarly Research Notices ◽

10.1155/2014/307963 ◽

2014 ◽

Vol 2014 ◽

pp. 1-4 ◽

Cited By ~ 1

Author(s):

Zongyao Hao ◽

Li Zhang ◽

Jun Zhou ◽

Xiansheng Zhang ◽

Haoqiang Shi ◽

...

Keyword(s):

Yttrium Aluminum Garnet ◽

High Rate ◽

Surgical Approaches ◽

Ho:Yag Laser ◽

Minimal Scarring ◽

Novel Approach ◽

Ureteral Injuries ◽

Yttrium Aluminum ◽

Invasive Management

The ureter is vulnerable during general, gynecologic, and urologic surgeries. The traditional open surgical approaches to treating the iatrogenic ureteral injuries have shown several disadvantages such as relatively high rate of severe complications. Although the applications of endourological techniques for management of lower ureteral strictures have been routinely introduced over the last 10 years, most of the different modalities were based on the utilization of hydrophilic instruments that can facilitate the traversal of strictures surrounded by the sutures with gradually increasing force. Interestingly, we have revealed the Ho:YAG laser as the outstanding auxiliary approach to incising the sutures during the ureteroscopy for its well-controlled penetration depth, minimal scarring, and precise cutting. As far as we know, the combined utilization of Ho:YAG laser to incise the sutures responsible for the strictures and double J ureteral stent for drainage has not been extensively reported. Normal ureters of the patients managed by this novel approach were shown by the follow-up 3-4 months later, which demonstrated that the available technique was promising to effectively treat the iatrogenic ureteral injuries.

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Repeat Surgery After Ureteroscopic Laser Lithotripsy With Attempted Complete Extraction of Fragments: Long-term Follow-up

Urology ◽

10.1016/j.urology.2015.03.019 ◽

2015 ◽

Vol 85 (6) ◽

pp. 1272-1278 ◽

Cited By ~ 9

Author(s):

Andrew J. Portis ◽

Mark A. Laliberte ◽

Andrew Heinisch

Keyword(s):

Laser Lithotripsy ◽

Repeat Surgery ◽

Complete Extraction ◽

Long Term Follow Up

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Therapy and prevention for mental health: What if mental diseases are mostly not brain disorders?

Behavioral and Brain Sciences ◽

10.1017/s0140525x1800105x ◽

2019 ◽

Vol 42 ◽

Cited By ~ 2

Author(s):

John P. A. Ioannidis

Keyword(s):

Mental Health ◽

Mental Disease ◽

Brain Disorders ◽

Social Stressors ◽

Labor Education ◽

Mental Diseases ◽

Long Term Follow Up ◽

Political Decisions

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.

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