scholarly journals Antifungal activity and mode of action of thymol and its synergism with nystatin against Candida species involved with infections in the oral cavity: an in vitro study

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Ricardo Dias de Castro ◽  
Trícia Murielly Pereira Andrade de Souza ◽  
Louise Morais Dornelas Bezerra ◽  
Gabriela Lacet Silva Ferreira ◽  
Edja Maria Melo de Brito Costa ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Oral Cavity ◽  
Mode Of Action ◽  
Candida Species ◽  
In Vitro Study ◽  
Vitro Study

scholarly journals Antifungal activity of nanoemulsions encapsulating oregano (Origanum vulgare) essential oil: in vitro study and application in Minas Padrão cheese

2018 ◽  
Vol 49 (4) ◽  
pp. 929-935 ◽  
Author(s):  
Carolina M. Bedoya-Serna ◽  
Gustavo C. Dacanal ◽  
Andrezza M. Fernandes ◽  
Samantha C. Pinho
Keyword(s):  
Antifungal Activity ◽  
Essential Oil ◽  
In Vitro Study ◽  
Vitro Study ◽  
Origanum Vulgare

Antifungal activity of four commercially available intense sweeteners against candida albicans - An In vitro study

2013 ◽  
Vol 3 (2) ◽  
pp. 60
Author(s):  
Subramaniam Ramanarayanan ◽  
Sakeenabi Basha ◽  
Mahesh Hiregoudar ◽  
PrashantGoudar Manjunath ◽  
Simpy Mittal ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Antifungal Activity ◽  
In Vitro Study ◽  
Vitro Study

scholarly journals An in vitro study of the antifungal activity of Trichoderma virens 7b and a profile of its non-polar antifungal components released against Ganoderma boninense

2016 ◽  
Vol 54 (11) ◽  
pp. 732-744 ◽  
Author(s):  
Lee Pei Lee Angel ◽  
Mohd Termizi Yusof ◽  
Intan Safinar Ismail ◽  
Bonnie Tay Yen Ping ◽  
Intan Nur Ainni Mohamed Azni ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
In Vitro Study ◽  
Vitro Study ◽  
Trichoderma Virens ◽  
Ganoderma Boninense

scholarly journals Changes in denture retention with denture adhesives and oral moisturizers for the oral cavity: an in vitro study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Naoya Ikemura ◽  
Yuji Sato ◽  
Junichi Furuya ◽  
Osamu Shimodaira ◽  
Kana Takeda ◽  
...  
Keyword(s):  
Oral Cavity ◽  
In Vitro Study ◽  
Vitro Study ◽  
Dry Mouth ◽  
Denture Adhesive ◽  
Retentive Force ◽  
Palatal Plate ◽  
Denture Adhesives ◽  
And Function

Abstract Background It is difficult to maintain complete dentures during meals in place. This in vitro study aimed to assess changes in denture retention between rest and function using denture adhesives and oral moisturizers in an oral cavity model. Methods The following test samples were applied between the palatal plate and the edentulous jaw ridge model: denture adhesive, denture adhesive for dry mouth, oral moisturizer, and denture moisturizer. The retentive force was measured under two conditions: at rest while immersed in water and during function with a 2.5-kg load applied. The plate was pulled perpendicular to the occlusal plane and the retentive force was measured using a digital force gauge. Results Under dry conditions, denture adhesive for dry mouth and oral moisturizer had a significantly higher retentive force than denture adhesive and denture moisturizer. After 30 min of immersion in water, the retentive force of the denture adhesive increased while that of the oral moisturizer decreased. After 30 min of function, the retentive force of the denture adhesive and denture adhesive for dry mouth remained high, while that of the oral moisturizer and denture moisturizer significantly decreased. Between rest and function, the retentive force of the denture adhesive and denture adhesive for dry mouth was high, and that of the oral moisturizer was low. Conclusions Immediately after use, denture adhesive for dry mouth exhibited high retentive force, but retention gradually decreased due to its water content.

scholarly journals The effect of sinefungin on the macromolecular biosynthesis of Leishmania species

2018 ◽  
Vol 49 (2) ◽  
pp. 137
Author(s):  
A. TZORA (Α. ΤΖΩΡΑ) ◽  
F. LAWRENCE ◽  
M. ROBERT-GERO
Keyword(s):  
Dna Synthesis ◽  
Mode Of Action ◽  
Rna Synthesis ◽  
In Vitro Study ◽  
Leishmania Species ◽  
Sensitive Strain ◽  
Vitro Study ◽  
No Inhibition ◽  
Main Target

The aim of the work presented here was the in vitro study of the action of the antibiotic sinefungin on the macromolecules DNA, RNA and the proteins of different isolates of Leismannia spp. in relation to the resistance or to the sensitivity of the strains examined. The mode of action of sinefungin of the Leishmania strains was detected by incorporating radiolabeled thymidine, uridine and leucine into promastigote forms, to study the synthesis of DNA, RNA and proteins respectively. In the sensitive strain L. tropica a statistically significant reduction of the rate of incorporation of thymidine to the DNA of the parasite, resulted to a 64% inhibition of leishmanial DNA synthesis by sinefungin at a concentration of 2.6 mM, when the time of action of the drug was 24 hours. In the sensitive strain L. tropica the reduction of the rate of incorporation of thymidine was depended on the concentration and the time of action of the drug. No inhibition of leishmanial RNA synthesis was observed. Our research showed that the action of the antibiotic sinefungin to the macromolecular biosynthesis of the protozoan Leishmania is independent of the strain and is strongly related with the expression of the sensitivity and the resistance of the strain. The main target of the antibiotic examined was the DNA of the Leishmania strains sensitive to the drug.

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