scholarly journals Invasive non-typhoidal Salmonella infections in sub-Saharan Africa: a systematic review on antimicrobial resistance and treatment

BMC Medicine ◽  
2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Bieke Tack ◽  
Jolien Vanaenrode ◽  
Jan Y. Verbakel ◽  
Jaan Toelen ◽  
Jan Jacobs
Keyword(s):  
Systematic Review ◽  
Antimicrobial Resistance ◽  
Sub Saharan Africa ◽  
Salmonella Infections ◽  
Sub Saharan

scholarly journals Evidence on collaboration of traditional and biomedical practitioners in the management of antimicrobial resistance in sub-Saharan Africa over 15 years: a systematic review protocol

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Aganze Gloire-Aimé Mushebenge ◽  
Mukanda Gedeon Kadima ◽  
Tivani Mashamba-Thompson ◽  
Manimbulu Nlooto
Keyword(s):  
Systematic Review ◽  
Antimicrobial Resistance ◽  
Treatment Failure ◽  
Healthcare Professionals ◽  
Sub Saharan Africa ◽  
Mapping Procedure ◽  
Traditional Health ◽  
Traditional Health Practitioners ◽  
Health Practitioners ◽  
Sub Saharan

Abstract Background The overuse of prescribed antimicrobials, concurrent use of traditional medicine, and prescribed antimicrobials have led to antimicrobial resistance. The absence of collaboration between traditional health practitioners and biomedically trained healthcare professionals can contribute to antimicrobial resistance, treatment failure, overdose, toxicity, and misadministration. This scoping review explores the evidence on collaboration between traditional health practitioners and biomedically trained healthcare professionals to reduce antimicrobial resistance and treatment failure in bacterial and viral diseases. Methods We will search for electronic databases such as Science Direct, Google Scholar, PubMed, and MEDLINE via EBSCOhost. We will also search reference lists of included studies. A two-stage mapping procedure will be carried out. Stage one (1) will consist of the title, abstracts, and full article screening, respectively. A pilot screening form guided by the defined eligibility criteria will be used. In stage two (2), data will be extracted from the included studies. Two reviewers will conduct parallel screening and data extraction. Mixed methods appraisal tool (MMAT) will be used to assess the quality of the included studies. NVIVO version 11 will be employed to aid pertinent thematic analysis. The outcomes of interest will be as follows: Primary outcome will be preventing and reducing antimicrobial resistance. The secondary effect is the effective collaboration between traditional healthcare practitioners and biomedically healthcare professionals. Discussion This review anticipates uncovering pertinent publications reporting the evidence of collaboration between traditional health practitioners and biomedically trained healthcare professionals to reduce antimicrobial resistance in sub-Saharan Africa. The sum-up of evidence acquired from the included studies will help guide future research. The result of the study will be print and electronically exposed. Systematic review registration PROSPERO, CRD42017072952

scholarly journals Evidence on collaboration of traditional and biomedical practitioners in the management of antimicrobial resistance in sub-Saharan Africa over 15 years: A systematic review protocol

2021 ◽  
Author(s):  
AGANZE GLOIRE-AIME MUSHEBENGE ◽  
MUKANDA Gedeon KADIMA ◽  
TIVANI Phosa MASHAMBA-THOMPSON ◽  
MANIMBULU NLOOTO
Keyword(s):  
Systematic Review ◽  
Antimicrobial Resistance ◽  
Treatment Failure ◽  
Healthcare Professionals ◽  
Sub Saharan Africa ◽  
Mapping Procedure ◽  
Traditional Health ◽  
Traditional Health Practitioners ◽  
Health Practitioners ◽  
Sub Saharan

Abstract Background The overuse of prescribed antimicrobials, concurrent use of traditional medicine, and prescribed antimicrobials have led to antimicrobial resistance. The absence of collaboration between traditional health practitioners and biomedically trained healthcare professionals can contribute to antimicrobial resistance, treatment failure, overdose, toxicity, and misadministration. This scoping review explores the evidence on collaboration between traditional health practitioners and biomedically trained healthcare professionals to reduce antimicrobial resistance and treatment failure in bacterial and viral diseases. Methods/design We will search for electronic databases such as Science Direct, Google Scholar, PubMed, MEDLINE via EBSCOhost. We will also search reference lists of included studies. A two-stage mapping procedure will be carried out. Stage one (1) will consist of the title, abstracts, and full article screening, respectively. A pilot screening form guided by the defined eligibility criteria will be used. Stage two (2), data will be extracted from the included studies. Two reviewers will conduct parallel screening and data extraction. Mixed methods appraisal tool (MMAT) will be used to assess the quality of the included studies. NVIVO version 11 will be employed to aid pertinent thematic analysis. The outcomes of interest will be as follows: Primary outcome will be preventing and reducing antimicrobial resistance. The secondary effect is the effective collaboration between traditional healthcare practitioners and biomedically healthcare professionals. Discussion This review anticipates uncovering pertinent publications reporting the evidence of collaboration between traditional health practitioners and biomedically trained healthcare professionals to reduce antimicrobial resistance in sub-Saharan Africa. The sum-up of evidence acquired from the included studies will help guide future research. The result of the study will be print and electronically exposed. Systematic review registration ID: PROSPERO CRD42017072952

scholarly journals Mapping the Aetiology and Antimicrobial Resistance Patterns of Maternal Bacterial Infection in Sub-Saharan Africa: A Systematic Review and Meta-Analysis Protocol

2021 ◽  
Author(s):  
Chikondi Isabel Joana Chapuma ◽  
Charlotte Van der veer ◽  
Edward J M Monk ◽  
Apatsa Selemani ◽  
David Kulapani ◽  
...  
Keyword(s):  
Systematic Review ◽  
Antimicrobial Resistance ◽  
Bacterial Infection ◽  
Meta Analysis ◽  
Sub Saharan Africa ◽  
Maternal Infection ◽  
Geographical Differences ◽  
Maternal Infections ◽  
Resistance Patterns ◽  
Sub Saharan

Abstract Background: Over two-thirds of global maternal deaths occur in Sub-Saharan Africa (SSA), with more than 200,000 deaths per year. Maternal sepsis causes 10% of these deaths, twice the proportion observed in high-income countries. In SSA, limited access to diagnostic microbiology facilities poses difficulties in promptly identifying and managing maternal infection and sepsis. This protocol describes a systematic review and meta-analysis that aims to summarize available data on the main bacterial agents causing maternal infections and their antibiotic susceptibility in SSA. Methods: Three electronic databases will be searched: MEDLINE, Embase and African Journals Online. Our search strategy will combine terms relating to laboratory-confirmed bacterial infection, pregnancy, postnatal period and SSA. We will include observational studies describing maternal bacterial infection's aetiology and antimicrobial resistance patterns in SSA. Two authors will perform study selection, data extraction and quality assessment. A third author will be consulted to resolve disagreements if they arise.We will summarize the proportion (and 95% confidence intervals) of samples testing positive for the most common bacteria and, depending on the data's availability and heterogeneity, examine results by country and/or region. If possible, we will describe trends over time and differentiate aetiological organisms and resistance/sensitivities by maternal infection sources. We will also undertake subgroup analyses based on HIV status, the invasive and non-invasive status of the infection, SSA sub-regions and mortality if there is adequate information to make such subgroup analysis feasible. Discussion: Data on the microbiologic outcomes for maternal infections in SSA are likely fragmented and not fully representative due to the limited availability of microbiology diagnostics and geographical differences in clinical and laboratory practices. If this is the case, policies and programme strategies to guide treatment and identify antimicrobial resistance threats in SSA settings will be challenging to target. Our systematic review aims to provide a comprehensive summary of the available data, describe the main organisms causing maternal infection and their sensitivities, and identify areas that require further research. Prospero ID: CRD42021238515

scholarly journals Epidemiology and antimicrobial resistance of Campylobacter spp. in animals in Sub-Saharan Africa: A systematic review

Heliyon ◽  
2020 ◽  
Vol 6 (3) ◽  
pp. e03537 ◽  
Author(s):  
Delfina Fernandes Hlashwayo ◽  
Betuel Sigaúque ◽  
Custódio Gabriel Bila
Keyword(s):  
Systematic Review ◽  
Antimicrobial Resistance ◽  
Sub Saharan Africa ◽  
Sub Saharan ◽  
Campylobacter Spp

Khat chewing and risky sexual behavior in Sub-Saharan Africa: a systematic review protocol

2013 ◽  
Vol 11 (12) ◽  
pp. 59-67 ◽  
Author(s):  
Amanuel Tesfay Gebremedhin ◽  
Hailay Abrha Gesesew ◽  
Tariku Dejene Demissie ◽  
Mirkuzie Woldie Kerie ◽  
Morankar Sudhakar
Keyword(s):  
Systematic Review ◽  
Sexual Behavior ◽  
Risky Sexual Behavior ◽  
Sub Saharan Africa ◽  
Systematic Review Protocol ◽  
Khat Chewing ◽  
Review Protocol ◽  
Sub Saharan

scholarly journals Predictors of lost to follow up from antiretroviral therapy among adults in sub-Saharan Africa: a systematic review and meta-analysis

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Hafte Kahsay Kebede ◽  
Lillian Mwanri ◽  
Paul Ward ◽  
Hailay Abrha Gesesew
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Meta Analysis ◽  
Sub Saharan Africa ◽  
Hiv Care ◽  
Care Services ◽  
Validity Assessment ◽  
Sub Saharan ◽  
Lost To Follow Up

Abstract Background It is known that ‘drop out’ from human immunodeficiency virus (HIV) treatment, the so called lost-to-follow-up (LTFU) occurs to persons enrolled in HIV care services. However, in sub-Saharan Africa (SSA), the risk factors for the LTFU are not well understood. Methods We performed a systematic review and meta-analysis of risk factors for LTFU among adults living with HIV in SSA. A systematic search of literature using identified keywords and index terms was conducted across five databases: MEDLINE, PubMed, CINAHL, Scopus, and Web of Science. We included quantitative studies published in English from 2002 to 2019. The Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instrument (JBI-MAStARI) was used for methodological validity assessment and data extraction. Mantel Haenszel method using Revman-5 software was used for meta-analysis. We demonstrated the meta-analytic measure of association using pooled odds ratio (OR), 95% confidence interval (CI) and heterogeneity using I2 tests. Results Thirty studies met the search criteria and were included in the meta-analysis. Predictors of LTFU were: demographic factors including being: (i) a male (OR = 1.2, 95% CI 1.1–1.3, I2 = 59%), (ii) between 15 and 35 years old (OR = 1.3, 95% CI 1.1–1.3, I2 = 0%), (iii) unmarried (OR = 1.2, 95% CI 1.2–1.3, I2 = 21%), (iv) a rural dweller (OR = 2.01, 95% CI 1.5–2.7, I2 = 40%), (v) unemployed (OR = 1.2, 95% CI 1.04–1.4, I2 = 58%); (vi) diagnosed with behavioral factors including illegal drug use(OR = 13.5, 95% CI 7.2–25.5, I2 = 60%), alcohol drinking (OR = 2.9, 95% CI 1.9–4.4, I2 = 39%), and tobacco smoking (OR = 2.6, 95% CI 1.6–4.3, I2 = 74%); and clinical diagnosis of mental illness (OR = 3.4, 95% CI 2.2–5.2, I2 = 1%), bed ridden or ambulatory functional status (OR = 2.2, 95% CI 1.5–3.1, I2 = 74%), low CD4 count in the last visit (OR = 1.4, 95% CI 1.1–1.9, I2 = 75%), tuberculosis co-infection (OR = 1.2, 95% CI 1.02–1.4, I2 = 66%) and a history of opportunistic infections (OR = 2.5, 95% CI 1.7–2.8, I2 = 75%). Conclusions The current review identifies demographic, behavioral and clinical factors to be determinants of LTFU. We recommend strengthening of HIV care services in SSA targeting the aforementioned group of patients. Trial registration Protocol: the PROSPERO Registration Number is CRD42018114418

scholarly journals Behavioural interventions promoting condom use among female sex workers in sub-Saharan Africa: a systematic review

2017 ◽  
Vol 16 (3) ◽  
pp. 257-268 ◽  
Author(s):  
Uchenna O Okafor ◽  
Rik Crutzen ◽  
Yauri Aduak ◽  
Sylvia Adebajo ◽  
Hubertus W Van den Borne
Keyword(s):  
Systematic Review ◽  
Condom Use ◽  
Sex Workers ◽  
Female Sex Workers ◽  
Sub Saharan Africa ◽  
Behavioural Interventions ◽  
Female Sex ◽  
Sub Saharan
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