scholarly journals Efficacy and safety of artemisinin-based combination therapy and chloroquine with concomitant primaquine to treat Plasmodium vivax malaria in Brazil: an open label randomized clinical trial

2018 ◽  
Vol 17 (1) ◽  
Author(s):  
André Daher ◽  
Dhelio Pereira ◽  
Marcus V. G. Lacerda ◽  
Márcia A. A. Alexandre ◽  
Cristiana T. Nascimento ◽  
...  
Pharmateca ◽  
2020 ◽  
Vol 13_2020 ◽  
pp. 87-95
Author(s):  
E.P. Sharapova Sharapova ◽  
L.I. Alekseeva Alekseeva ◽  
E.A. Taskina Taskina ◽  
N.G. Kashevarova Kashevarova ◽  
S.G. Anikin Anikin ◽  
...  

2018 ◽  
Vol 67 (10) ◽  
pp. 1543-1549 ◽  
Author(s):  
Cindy S Chu ◽  
Aung Pyae Phyo ◽  
Khin Maung Lwin ◽  
Htun Htun Win ◽  
Thida San ◽  
...  

Vivax malaria relapses frequently even in low-transmission settings. Chloroquine delays but does not prevent recurrences. Adding primaquine to a slowly eliminated schizonticide significantly reduces recurrences and improves hematocrit, but this advantage is offset by hemolysis in G6PD-deficient females.


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