scholarly journals Quality of life in patients with stable coronary artery disease submitted to percutaneous, surgical, and medical therapies: a cohort study

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Lucas Molinari Veloso da Silveira ◽  
Adriana Silveira Almeida ◽  
Felipe C. Fuchs ◽  
Aline Gonçalves Silva ◽  
Marcelo Balbinot Lucca ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Short Form ◽  
Artery Bypass ◽  
Stable Coronary Artery Disease ◽  
Therapeutic Strategies ◽  
Artery Disease

Abstract Background Clinical, surgical, and percutaneous strategies similarly prevent major cardiovascular events in patients with stable coronary artery disease (CAD). The possibility that these strategies have differential effects on health-related quality of life (HRQoL) has been debated, particularly in patients treated outside clinical trials. Methods We assigned 454 patients diagnosed with CAD during an elective diagnostic coronary angiography to coronary artery bypass grafting (CABG), percutaneous coronary intervention (PCI), or optimal medical treatment (OMT), and followed them for an average of 5.2 ± 1.5 years. HRQoL was assessed using a validated Brazilian version of the 12-Item Short-Form Health Survey questionnaire. The association between therapeutic strategies and quality of life scores was tested using variance analysis and adjusted for confounders in a general linear model. Results There were no differences in the mental component summary scores in the follow-up evaluation by therapeutic strategies: 51.4, 53.7, and 52.3 for OMT, PCI, and CABG, respectively. Physical component summary scores were higher in the PCI group than the CABG and OMT groups (46.4 vs. 42.9 and 43.8, respectively); however, these differences were no longer different after adjustment for confounding variables. Conclusion In a long-term follow-up of patients with stable CAD, HRQoL did not differ in patients treated by medical, percutaneous, or surgical treatments.

scholarly journals Quality of Life in Patients with Stable Coronary Artery Disease Submitted to Percutaneous, Surgical and Medical Therapies: A Cohort Study

2021 ◽  
Author(s):  
Lucas Molinari Veloso da Silveira ◽  
Adriana Silveira Almeida ◽  
Felipe C. Fuchs ◽  
Aline Gonçalves Silva ◽  
Marcelo Balbinot Lucca ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Short Form ◽  
Artery Bypass ◽  
Stable Coronary Artery Disease ◽  
Therapeutic Strategies ◽  
Artery Disease

Abstract Background: Clinical, surgical and percutaneous strategies have been shown similar effectiveness in the prevention of major cardiovascular events in patients with stable coronary artery disease (CAD). The possibility that these strategies have differential effects over health-related quality of life (HRQoL) has been debated, particularly in patients treated outside clinical trials.Methods: 454 patients diagnosed with coronary artery disease during an elective diagnostic coronary angiography were assigned to Coronary Artery Bypass Grafting (CABG), Percutaneous Coronary Intervention (PCI) or optimal medical treatment (OMT), and followed on average for 6.0 ± 1.9 years. HRQoL was assessed by a validated Brazilian version of the 12-Item Short-Form Health Survey (SF-12) questionnaire. The association between therapeutic strategies and scores of QoL were tested by ANOVA and adjusted for confounding in a general linear model. Results: There was no difference in the Mental Component Summary (MCS) scores in the follow-up evaluation by therapeutic strategies: 51.4, 53.7 and 52.3, respectively, for MT, PCI, and CABG. Physical Component Summary (PCS) scores were higher in the PCI group, when compared to the CABG and MT (46.4 vs. 42.9 and 43.8, respectively), but these differences were no longer different after adjustment for confounding variables.Conclusion: In a long-term follow-up of patients with stable CAD, HRQoL was not different in patients treated by medical, percutaneous or surgical treatments.

scholarly journals Prospective cohort study of elderly patients with coronary artery disease: impact of frailty on quality of life and outcome

Open Heart ◽  
2020 ◽  
Vol 7 (2) ◽  
pp. e001314
Author(s):  
Shouaib Qayyum ◽  
Jennifer Ann Rossington ◽  
Raj Chelliah ◽  
Joseph John ◽  
Benjamin J Davidson ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Short Form ◽  
Composite Score ◽  
Coronary Syndrome ◽  
Mental Composite Score ◽  
Artery Disease

BackgroundElderly, frail patients are often excluded from clinical trials so there is lack of data regarding optimal management when they present with symptomatic coronary artery disease (CAD).ObjectiveThe aim of this observational study was to evaluate an unselected elderly population with CAD for the occurrence of frailty, and its association with quality of life (QoL) and clinical outcomes.MethodsConsecutive patients aged ≥80 years presenting with CAD were prospectively assessed for frailty (Fried frailty phenotype (FFP), Edmonton frailty scale (EFS)), QoL (Short form survey (SF-12)) and comorbidity (Charlson Comorbidity Index (CCI)). Patients were re-assessed at 4 months to determine any change in frailty and QoL status as well as the clinical outcome.ResultsOne hundred fifty consecutive patients with symptomatic CAD were recruited in the study. The mean age was 83.7±3.2 years, 99 (66.0%) were men. The clinical presentation was stable angina in 68 (45.3%), the remainder admitted with an acute coronary syndrome including 21 (14.0%) with ST-elevation myocardial infarction. Frailty was present in 28% and 26% by FFP and EFS, respectively, and was associated with a significantly higher CCI (7.5±2.4 in frail, 6.2±2.2 in prefrail, 5.9±1.6 in those without frailty, p=0.005). FFP was significantly related to the physical composite score for QoL, while EFS was significantly related to the mental composite score for QoL (p=0.003). Treatment was determined by the cardiologist: percutaneous coronary intervention in 51 (34%), coronary artery bypass graft surgery in 15 (10%) and medical therapy in 84 (56%). At 4 months, 14 (9.3%) had died. Frail participants had the lowest survival. Cardiovascular symptom status and the mental composite score of QoL significantly improved (52.7±11.5 at baseline vs 55.1±10.6 at follow-up, p=0.04). However, overall frailty status did not significantly change, nor the physical health composite score of QoL (37.2±11.0 at baseline vs 38.5±11.3 at follow-up, p=0.27).ConclusionsIn patients referred to hospital with CAD, frailty is associated with impaired QoL and a high coexistence of comorbidities. Following cardiac treatment, patients had improvement in cardiovascular symptoms and mental component of QoL.

scholarly journals The argument of the ORBITA study: angioplasty is useless

2020 ◽  
Vol 22 (Supplement_E) ◽  
pp. E34-E36
Author(s):  
Leonardo Bolognese
Keyword(s):  
Quality Of Life ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Functional Capacity ◽  
Coronary Angioplasty ◽  
Stable Coronary Artery Disease ◽  
Artery Disease ◽  
Revascularization Procedures ◽  
Vessel Coronary Artery

Abstract The goal of treatment in stable coronary artery disease is to improve prognosis and quality of life of the patients. International Guidelines support revascularization procedures for symptomatic patients unresponsive to optimal medical treatment. Previous studies demonstrated, in fact, the therapeutic efficacy of coronary angioplasty in reducing angina and improving the functional capacity of these patients. The ORBITA study, recently published, challenged these assertions by demonstrating the lack of benefit of angioplasty over placebo in terms of effort tolerance in a population of patients with single-vessel coronary artery disease. What lesson could we learn from the ORBITA study?

scholarly journals Health-Related Quality of Life among Patients with Coronary Artery Disease: A Post-Treatment Follow-Up Study in Iran

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Shahram Tofighi ◽  
Aliasghar Ahmad Kiadaliri ◽  
Jamil Sadeghifar ◽  
Mehdi Raadabadi ◽  
Jahanara Mamikhani
Keyword(s):  
Quality Of Life ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Health Related Quality ◽  
Summary Scale ◽  
Related Quality ◽  
Health Related ◽  
Artery Disease

Objective.To examine the changes in health-related quality of life (HRQoL) in patients with coronary artery disease (CAD) in terms of age, gender, and treatment strategy in Iran.Methods and Materials.Forty-nine patients responded to the Iranian version of the 36-item short form (SF-36) questionnaire to evaluate the HRQoL at first and third year after treatment. The paired and independent Wilcoxon rank-sum tests were used for within and between comparisons, respectively. Multivariate regression analysis was used to analyze the predictors of changes at HRQoL.Results.In general, during followup, the mental component summary scale improved, and the physical component summary scale declined. The results of multiple regression showed that the score at the first year post-treatment was the main predictor of HRQoL at follow up. Moreover, after adjusting for other covariates, receiving PTCA and being at older age were related to lower scores at followup, but these were not statistically significant in most cases.Conclusion.The HRQoL significantly changed from one to three years after treatment in patients with CAD. While, the physical health deteriorated during two-year follow up, mental health improved at the same time period. Generally, there were no significant differences at changes of HRQoL in terms of treatment, age, and gender.

The Meaning of Life Related to Heart Disease and Its Relationship to Quality of Life After Repeat Coronary Artery Angioplasty

2020 ◽  
Vol 26 (1) ◽  
pp. 48-55
Author(s):  
Masoomeh Barsaei ◽  
Hossein Feizollahzadeh ◽  
Faranak Jabbarzadeh ◽  
Hadi Hasankhani ◽  
Reza Shabanloei
Keyword(s):  
Quality Of Life ◽  
Coronary Artery Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Short Form ◽  
Pearson Correlation ◽  
Meaning Of Life ◽  
Correlation Study ◽  
Artery Disease

PurposeFollowing angioplasty for coronary artery disease, patients may search for a new meaning of life. The purpose of this study was to determine patients' meaning of life related to heart disease and its relationship to quality of life after repeat coronary artery angioplasty.MethodsThe current descriptive-correlation study recruited 144 patients with coronary artery disease admitted to hospitals in Karaj, Iran. Data were collected using a demographics questionnaire, the Meaning in Heart Disease (MHD) instrument, and the Iranian version of the Short Form Health Survey (SF-12), and were analyzed with descriptive statistics and the Pearson correlation.FindingsThere was a significant relationship between the meaning of life related to heart disease (creating illusions, changing goals, reattribution, and meaning congruence) and quality of life scores (p <.05).ConclusionThe majority of the patients undergoing repeat angioplasty used the creation of illusions to support a positive attitude toward their heart disease. Nursing interventions based on the individual patient's meaning of life can promote health and life quality.

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