Evaluation of health-related quality of life of Covid-19 patients: a hospital-based study in South Central Ethiopia

Abstract Background Covid-19 causes a wide range of symptoms in patients, ranging from mild manifestations to severe disease and death. This study assessed the health-related quality of life (HRQOL) and associated factors of Covid-19 patients using primary data from confirmed cases in South Central Ethiopia. Methods We employed a facility-based, cross-sectional study design and conducted the study at the Bokoji Hospital Covid-19 treatment centre. A structured questionnaire and the EQ-5D-3L scale were used to collect the data for analysis. The HRQOL results measured by the EQ-5D-3L tool were converted to a health state utility (HSU) using the Zimbabwe tariff. The average health utility index and HSU–visual analogue scale across diverse sociodemographic and clinical characteristics were compared using the Mann–Whitney U test or Kruskal–Wallis test. We employed a multiple linear regression to examine factors associated with HSU values simultaneously. The data were analysed using STATA version 15. Results The overall mean HSU score from the EQ-5D was 0.688 (SD: 0.285), and the median was 0.787 (IQR 0.596, 0.833). The mean HSU from the visual analogue scale score was 0.69 (SD: 0.129), with a median of 0.70 (IQR 0.60, 0.80). Those who received dexamethasone and intranasal oxygen supplement, those with comorbidity, those older than 55 years and those with a hospital stay of more than 15 days had significantly lower HSU scores than their counterparts (p < .001). Conclusion Covid-19 substantially impaired the HRQOL of patients in Ethiopia, especially among elderly patients and those with comorbidity. Therefore, clinical follow-up and psychological treatment should be encouraged for these groups. Moreover, the health utility values from this study can be used to evaluate quality adjusted life years for future cost-effectiveness analyses of prevention and treatment interventions against Covid-19.

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Evaluation of Health-Related Quality of Life of Covid-19 Patients: A Hospital-Based Study in South Central Ethiopia

10.21203/rs.3.rs-743918/v1 ◽

2021 ◽

Author(s):

Abdene Kaso ◽

Gebi Agero ◽

Zewdu Hurisa ◽

Taha Kaso ◽

Helen Ali Ewune ◽

...

Keyword(s):

Quality Of Life ◽

Visual Analogue Scale ◽

Analogue Scale ◽

Health Utility ◽

Health Related Quality ◽

Central Ethiopia ◽

South Central ◽

Related Quality ◽

Health Related

Abstract Background: Covid-19 causes a wide range of symptoms in patients, ranging from mild manifestations to severe disease and death. This study assessed the health-related quality of life (HRQOL) and associated factors of Covid-19 patients using primary data from confirmed cases in South Central Ethiopia.Methods: We employed a facility-based, cross-sectional study design and conducted the study at the Bokoji Hospital Covid-19 treatment centre. A structured questionnaire and the EQ-5D-3L scale were used to collect the data for analysis. The HRQOL results measured by the EQ-5D-3L tool were converted to a health state utility (HSU) using the Zimbabwe tariff. The average health utility index and HSU–visual analogue scale across diverse sociodemographic and clinical characteristics were compared using the Mann-Whitney U test or Kruskal-Wallis test. We employed a multiple linear regression to examine the associations of predictor variables with HSU values simultaneously. The data were analysed using STATA version 15. Results: The overall mean HSU score from the EQ-5D was 0.688 (SD: 0.285), and the median was 0.787 (IQR: 0.596, 0.833). The mean HSU from the visual analogue scale score was 0.69 (SD: 0.129), with a median of 0.70 (IQR: 0.60, 0.80). Those who received dexamethasone and intranasal oxygen supplement, those with comorbidity, those older than 55 years and those with a hospital stay of more than 15 days had significantly lower HSU scores than their counterparts (p<.001).Conclusion: Covid-19 substantially impaired the HRQOL of patients in Ethiopia, especially among elderly patients and those with comorbidity. Therefore, clinical follow-up and psychological treatment should be encouraged for these groups. Moreover, the health utility values from this study can be used to evaluate quality adjusted life years for future cost-effectiveness analyses of prevention and treatment interventions against Covid-19.

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The effectiveness of the Visual Analogue Scale 8 in measuring health-related quality of life for COPD patients

Respiratory Medicine ◽

10.1053/rmed.2000.0950 ◽

2000 ◽

Vol 94 (12) ◽

pp. 1192-1199 ◽

Cited By ~ 16

Author(s):

O. NISHIYAMA ◽

H. TANIGUCHI ◽

Y. KONDOH ◽

K. NISHIMURA ◽

R. SUZUKI ◽

...

Keyword(s):

Quality Of Life ◽

Visual Analogue Scale ◽

Analogue Scale ◽

Health Related Quality ◽

Copd Patients ◽

Related Quality ◽

Health Related ◽

Scale 8

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Health Professionals' Assessment of Health Related Quality of Life Values for Oral Clefting by Age Using a Visual Analogue Scale Method

The Cleft Palate-Craniofacial Journal ◽

10.1597/05-066 ◽

2005 ◽

Author(s):

George Wehby ◽

Robert Ohsfeldt ◽

Jeffrey Murray

Keyword(s):

Quality Of Life ◽

Visual Analogue Scale ◽

Health Professionals ◽

Analogue Scale ◽

Health Related Quality ◽

Scale Method ◽

Related Quality ◽

Health Related ◽

Life Values

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Health-related quality of life and its predictors among adults living with HIV/AIDS and receiving antiretroviral therapy in Pakistan

Quality of Life Research ◽

10.1007/s11136-021-02771-y ◽

2021 ◽

Author(s):

Ali Ahmed ◽

Muhammad Saqlain ◽

Naila Bashir ◽

Juman Dujaili ◽

Furqan Hashmi ◽

...

Keyword(s):

Quality Of Life ◽

Antiretroviral Therapy ◽

Visual Analogue Scale ◽

Analogue Scale ◽

Health Related Quality ◽

Related Quality ◽

Health Related ◽

Living With Hiv ◽

Eq Vas

Abstract Background Health-related quality of life (HRQoL) is considered to be the fourth 90 of UNAIDS 90-90-90 target to monitor the effects of combination antiretroviral therapy (ART). ART has significantly increased the life expectancy of people living with HIV/AIDS (PLWHA). However, the impact of chronic infection on HRQoL remains unclear, while factors influencing the HRQoL may vary from one country to another. The current study aimed to assess HRQoL and its associated factors among PLWHA receiving ART in Pakistan. Methods A cross-sectional descriptive study was conducted among PLWHA attending an ART centre of a tertiary care hospital in Islamabad, Pakistan. HRQoL was assessed using a validated Urdu version of EuroQol 5 dimensions 3 level (EQ-5D-3L) and its Visual Analogue Scale (EQ-VAS). Results Of the 602 patients included in the analyses, 59.5% (n = 358) reported no impairment in self-care, while 63.1% (n = 380) were extremely anxious/depressed. The overall mean EQ-5D utility score and visual analogue scale (EQ-VAS) score were 0.388 (SD: 0.41) and 66.20 (SD: 17.22), respectively. Multivariate linear regression analysis revealed that the factors significantly associated with HRQoL were: female gender; age > 50 years; having primary and secondary education; > 1 year since HIV diagnosis; HIV serostatus AIDS-converted; higher CD 4 T lymphocytes count; detectable viral load; and increased time to ART. Conclusions The current findings have shown that PLWHA in Pakistan adherent to ART had a good overall HRQoL, though with significantly higher depression. Some of the factors identified are amenable to institution-based interventions while mitigating depression to enhance the HRQoL of PLWHA in Pakistan. The HRQoL determined in this study could be useful for future economic evaluation studies for ART and in designing future interventions.

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Assessment of Health-Related Quality of Life between People with Parkinson’s Disease and Non-Parkinson’s: Using Data Drawn from the ‘100 for Parkinson’s’ Smartphone-Based Prospective Study

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph15112538 ◽

2018 ◽

Vol 15 (11) ◽

pp. 2538 ◽

Cited By ~ 3

Author(s):

Xiaojing Fan ◽

Duolao Wang ◽

Bruce Hellman ◽

Mathieu Janssen ◽

Gerben Bakker ◽

...

Keyword(s):

Quality Of Life ◽

Visual Analogue Scale ◽

Prospective Study ◽

Analogue Scale ◽

Mean Difference ◽

Health Related Quality ◽

Related Quality ◽

Health Related ◽

The Mean

Background: This study aims to assess the specific difference of the health-related quality of life between people with Parkinson’s and non-Parkinson’s. Methods: A total of 1710 people were drawn from a prospective study with a smartphone-based survey named ‘100 for Parkinson’s’ to assess health-related quality of life. The EQ-5D-5L descriptive system and the EQ visual analogue scale were used to measure health-related quality of life and a linear mixed model was used to analyze the difference. Results: The mean difference of EQ-5D-5L index values between people with Parkinson’s and non-Parkinson’s was 0.15 (95%CI: 0.12, 0.18) at baseline; it changed to 0.17 (95%CI: 0.14, 0.20) at the end of study. The mean difference of EQ visual analogue scale scores between them increased from 10.18 (95%CI: 7.40, 12.96) to 12.19 (95%CI: 9.41, 14.97) from baseline to the end of study. Conclusion: Data can be captured from the participants’ own smart devices and support the notion that health-related quality of life for people with Parkinson’s is lower than non-Parkinson’s. This analysis provides useful evidence for the EQ-5D instrument and is helpful for public health specialists and epidemiologists to assess the health needs of people with Parkinson’s and indirectly improve their health status.

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Impact of Spinal Muscular Atrophy on Caregivers’ Daily Activities and Health-Related Quality of Life

10.21203/rs.3.rs-46975/v1 ◽

2020 ◽

Author(s):

Er Chen ◽

Komal Bawa ◽

Josh Noone ◽

Sarah Whitmire ◽

Daniel Buchenberger ◽

...

Keyword(s):

Quality Of Life ◽

Visual Analogue Scale ◽

Motor Function ◽

Analogue Scale ◽

Muscular Atrophy ◽

Daily Activities ◽

Health Related Quality ◽

Related Quality ◽

Health Related

Abstract Background:Spinal muscular atrophy (SMA) is a genetic debilitating disease affecting approximately 10,000 individuals in the United States. Individuals with SMA frequently require caregiver support and care. Through a partnership with Cure SMA, we surveyed caregivers of individuals with SMA <18 years of age to understand the impact of SMA on caregivers with respect to their daily activities and health-related quality of life (HRQoL). In addition to structured questions, a standardized HRQoL instrument, the EQ-5D-5L and visual analogue scale, were administered.Results:The sample consisted of 45 unpaid caregivers of children with SMA. Of them, 22% reported that they were sole caregivers that received no additional caregiving support and 98% were parents of an affected individual. The majority of caregivers cared for individuals with type 2 (58%), followed by type 1 (38%) and type 3 (4%) SMA. Sixty-four percent of the individuals with SMA were able to sit without support or better, while 31% had some motor function and 5% reported no motor function. Across SMA types, caregivers reported spending a median 80 hours per month managing the overall care and treatment of the affected individual.. Most of the individuals (91%) were reported to have received nusinersen. Caregiver time investment correlated directly with disease severity measured by both SMA type and patient motor function level. The mean EQ-5D utility score for caregivers was 0.71 and their mean score on the EQ-5D visual analogue scale was 76. Specifically, 42% of caregivers reported any inability to do their usual activities and 73% reported any anxiety or depression.Conclusions:SMA negatively affects caregiver’s daily activities and HRQoL, representing a substantial burden. Disease severity is associated with an increasing amount of time required for care and support for patients with SMA and a decrease in a caregiver’s HRQoL. As treatments become available, evaluation of these treatments should include effects on the family as well.

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Visual Analogue Scale, Urinary Incontinence Severity Score and 15 D’Psychometric Testing of Three Different Health-related Quality-of-life Instruments for Urinary Incontinent Women

Scandinavian Journal of Urology and Nephrology ◽

10.1080/003655901753367587 ◽

2001 ◽

Vol 35 (6) ◽

pp. 476-483 ◽

Cited By ~ 79

Author(s):

B. Stach-Lempinen, E. Kujansuu, P. Lai

Keyword(s):

Quality Of Life ◽

Urinary Incontinence ◽

Visual Analogue Scale ◽

Severity Score ◽

Analogue Scale ◽

Health Related Quality ◽

Related Quality ◽

Health Related ◽

Quality Of Life Instruments

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Health Professionals’ Assessment of Health-Related Quality of Life Values for Oral Clefting by Age Using a Visual Analogue Scale Method

The Cleft Palate-Craniofacial Journal ◽

10.1597/05-066.1 ◽

2006 ◽

Vol 43 (4) ◽

pp. 383-391 ◽

Cited By ~ 19

Author(s):

George L. Wehby ◽

Robert L. Ohsfeldt ◽

Jeffrey C. Murray

Keyword(s):

Quality Of Life ◽

Visual Analogue Scale ◽

Cleft Palate ◽

Health Professionals ◽

Analogue Scale ◽

The United States ◽

Health Related Quality ◽

Related Quality ◽

Health Related

Objective To elicit health-related quality of life (HRQL) values associated with oral clefting by age using a visual analogue scale, and to explore the appropriateness of using health professionals as evaluators. Methods A representative group of health professionals working on craniofacial and/or cleft palate teams in the United States was sampled. Values (between 0 and 1) representing the HRQL associated with isolated and nonisolated oral clefting for infants, children, adolescents, and adults were obtained. The relationships between selected evaluator characteristics and values were also assessed. Results Of 330 professionals surveyed, 133 (40%) completed and returned reliable evaluations. Overall, HRQL values were clustered toward the right tail of the scale, indicating modest decreases in HRQL. Most evaluators reported feeling confident in completing the evaluations. HRQL values seemed to vary by team type (cleft palate only versus cleft palate/craniofacial care) and geographic location, but no major differences were found overall for any selected evaluator characteristics. Conclusions This study provides HRQL values for oral clefting based on preferences of health professionals that may be useful in evaluating the effectiveness and cost-effectiveness of prevention and treatment strategies, including those carried out in clinical trial studies. The clustered pattern of HRQL values suggests either a consensus among evaluators of a limited burden of oral clefting or an overall lack of understanding of the evaluation task.

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