Therapeutic properties of a vector carrying the HSV thymidine kinase and GM-CSF genes and delivered as a complex with a cationic copolymer

Irina V Alekseenko; Eugene V Snezhkov; Igor P Chernov; Victor V Pleshkan; Victor K Potapov; Alexander V Sass; Galina S Monastyrskaya; Eugene P Kopantzev; Tatyana V Vinogradova; Yuri V Khramtsov; Alexey V Ulasov; Andrey A Rosenkranz; Alexander S Sobolev; Olga A Bezborodova; Anna D Plyutinskaya; Elena R Nemtsova; Raisa I Yakubovskaya; Eugene D Sverdlov

doi:10.1186/s12967-015-0433-0

Therapeutic properties of a vector carrying the HSV thymidine kinase and GM-CSF genes and delivered as a complex with a cationic copolymer

Journal of Translational Medicine ◽

10.1186/s12967-015-0433-0 ◽

2015 ◽

Vol 13 (1) ◽

pp. 78 ◽

Cited By ~ 20

Author(s):

Irina V Alekseenko ◽

Eugene V Snezhkov ◽

Igor P Chernov ◽

Victor V Pleshkan ◽

Victor K Potapov ◽

...

Keyword(s):

Thymidine Kinase ◽

Gm Csf ◽

Therapeutic Properties ◽

Hsv Thymidine Kinase

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Increased Anti-tumor Effect by a Combination of HSV Thymidine Kinase Suicide Gene Therapy and Interferon-γ/GM-CSF Cytokine Gene Therapy in CT26 Tumor Model

Journal of Korean Medical Science ◽

10.3346/jkms.2005.20.6.932 ◽

2005 ◽

Vol 20 (6) ◽

pp. 932 ◽

Cited By ~ 2

Author(s):

Sung Hyun Yang ◽

Tae Keun Oh ◽

Seung Taik Kim

Keyword(s):

Gene Therapy ◽

Thymidine Kinase ◽

Tumor Model ◽

Suicide Gene ◽

Interferon Γ ◽

Cytokine Gene ◽

Gm Csf ◽

Cytokine Gene Therapy ◽

Hsv Thymidine Kinase ◽

Ct26 Tumor

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Glucose transport and apoptosis after gene therapy with HSV thymidine kinase

European Journal of Nuclear Medicine ◽

10.1007/s002590100644 ◽

2001 ◽

Vol 28 (11) ◽

pp. 1690-1696 ◽

Cited By ~ 20

Author(s):

Uwe Haberkorn ◽

Annette Altmann ◽

Huse Kamencic ◽

Iris Morr ◽

Ulrike Traut ◽

...

Keyword(s):

Gene Therapy ◽

Thymidine Kinase ◽

Glucose Transport ◽

Hsv Thymidine Kinase

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Correlation of Deoxycytidine Deaminase, Thymidine Kinase and Polymerase Alpha Activity and Deoxycytidine Deaminase Gene Expression In Vivo with Clinical Response to TAD-9+GM-CSF Induction Therapy in Acute Myeloid Leukemia

Acute Leukemias VI - Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ◽

10.1007/978-3-642-60377-8_42 ◽

1997 ◽

pp. 252-259

Author(s):

G. Jahns-Streubel ◽

M. Unterhalt ◽

E. Schleyer ◽

C. Reuter ◽

B. Wörmann ◽

...

Keyword(s):

Gene Expression ◽

Acute Myeloid Leukemia ◽

Clinical Response ◽

Thymidine Kinase ◽

Induction Therapy ◽

Alpha Activity ◽

Gm Csf ◽

Deoxycytidine Deaminase ◽

Acute Myeloid

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Coordinate modulation of transfected HSV thymidine kinase and human globin genes

Cell ◽

10.1016/0092-8674(83)90217-9 ◽

1983 ◽

Vol 35 (1) ◽

pp. 149-155 ◽

Cited By ~ 21

Author(s):

Raymond S. Roginski ◽

Arthur I. Skoultchi ◽

Paula Henthorn ◽

Oliver Smithies ◽

Nancy Hsiung ◽

...

Keyword(s):

Thymidine Kinase ◽

Globin Genes ◽

Hsv Thymidine Kinase

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HSV-thymidine kinase: a molecular target for transfection imaging in gene therapy of cancer

Antiviral Research ◽

10.1016/0166-3542(95)94850-2 ◽

1995 ◽

Vol 26 (3) ◽

pp. A307 ◽

Cited By ~ 1

Keyword(s):

Gene Therapy ◽

Thymidine Kinase ◽

Molecular Target ◽

Hsv Thymidine Kinase ◽

Kinase A

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Connexin Over-Expression Differentially Suppresses Glioma Growth and Contributes to the Bystander Effect Following HSV-Thymidine Kinase Gene Therapy

Cell Communication & Adhesion ◽

10.1080/15419060600631771 ◽

2006 ◽

Vol 13 (1-2) ◽

pp. 79-92 ◽

Cited By ~ 21

Author(s):

Tomas Jimenez ◽

W. Paul Fox ◽

Christian C. G. Naus ◽

Jacques Galipeau ◽

Daniel J. Belliveau

Keyword(s):

Gene Therapy ◽

Thymidine Kinase ◽

Bystander Effect ◽

Thymidine Kinase Gene ◽

Kinase Gene ◽

Over Expression ◽

Glioma Growth ◽

Hsv Thymidine Kinase

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SC-07 * CYCLIC INTRANASAL APPLICATION OF NEURAL STEM CELL-MEDIATED ENZYM/PRODRUG THERAPY USING A NOVEL HSV-THYMIDINE KINASE VARIANT INHIBITS INTRACEREBRAL GLIOMA GROWTH AND IMPROVES SURVIVAL

Neuro-Oncology ◽

10.1093/neuonc/nou275.7 ◽

2014 ◽

Vol 16 (suppl 5) ◽

pp. v198-v198

Author(s):

L. Duhrsen ◽

M. Reitz ◽

M. Henze ◽

J. Sedlacik ◽

K. Riecken ◽

...

Keyword(s):

Stem Cell ◽

Thymidine Kinase ◽

Neural Stem Cell ◽

Intranasal Application ◽

Glioma Growth ◽

Hsv Thymidine Kinase

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Pharmacological properties of orally active inhibitors of herpes simplex virus (HSV) thymidine kinase

Antiviral Research ◽

10.1016/s0166-3542(97)83159-2 ◽

1997 ◽

Vol 34 (2) ◽

pp. A47

Author(s):

MJ Mulqueen ◽

AM Watkins ◽

PJ Dunford ◽

P. Wong Kai-In ◽

G Thomas ◽

...

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Pharmacological Properties ◽

Simplex Virus ◽

Orally Active ◽

Hsv Thymidine Kinase

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Phosphorylation of herpes simplex virus (HSV) thymidine kinase (TK)-specific nucleosides: Effects of protein-binding, exogenous thymidine (dT), and the de novo pathway (dnp)

Antiviral Research ◽

10.1016/0166-3542(92)90116-m ◽

1992 ◽

Vol 17 ◽

pp. 52

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Protein Binding ◽

Thymidine Kinase ◽

De Novo ◽

Simplex Virus ◽

Hsv Thymidine Kinase

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The transfer and stable integration of the HSV thymidine kinase gene into mouse cells

Cell ◽

10.1016/0092-8674(78)90308-2 ◽

1978 ◽

Vol 14 (1) ◽

pp. 133-141 ◽

Cited By ~ 209

Author(s):

A Pellicer

Keyword(s):

Thymidine Kinase ◽

Thymidine Kinase Gene ◽

Kinase Gene ◽

Stable Integration ◽

Mouse Cells ◽

Hsv Thymidine Kinase

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