Complications after intramedullary nail fixation of pathological versus non-pathological femoral shaft fractures: a retrospective cohort study in 233 patients

Abstract Background Postoperative adverse events after intramedullary nailing have been reported in patients with metastatic pathological and non-pathological femoral fractures. Other consequences to be considered are readmission and reoperation. Few studies have compared the risks of postoperative adverse events, reoperation, and readmission after intramedullary nailing of pathological and non-pathological femur fractures. This study was designed to test the hypothesis that patients with pathological femoral fractures had more adverse events, readmission, and reoperation following surgical fixation than non-pathological femoral fractures. Methods This was a retrospective observational cohort study, conducted at an academic medical center in Thailand. The data from patients with femoral shaft fractures undergoing long intramedullary nailing, from June 1, 2006, to June 30, 2020, were included. Patients who had a pathological fracture from a primary bone tumor, metabolic bone disease, or inadequate/missing information were excluded. Patients with pathological fractures from metastatic bone disease were assigned to be the pathological group whereas those with traumatic fractures were assigned to be the non-pathological group. The primary outcome was the risk of inpatient adverse events as compared between the two groups. The secondary outcome was the risk of consequences after discharge as compared between the two groups. Outcomes were analyzed by using multivariate logistic regression analysis. Results The total number of patients was 48 in the pathological fracture group and 185 in the non-pathological group. There were significantly higher rates of surgical and medical adverse events in patients with pathological fractures compared to patients with non-pathological fractures. After adjusting for potential confounding factors in multivariate regression analysis, patients with pathological fractures had higher odds of both adverse surgical (adjusted OR 2.43, 95 % CI 1.15–5.13) and medical adverse events (adjusted OR 2.81, 95 % CI 1.13–7.03). Conclusions Patients with metastatic pathological femoral shaft fractures undergoing intramedullary nailing were more likely to experience postoperative adverse events than patients with non-pathological fractures.

Download Full-text

Adverse Events following Intramedullary Nailing in Metastatic Pathological versus Non-Pathological Femoral Shaft Fractures: A Retrospective Comparative Study

10.21203/rs.3.rs-488243/v1 ◽

2021 ◽

Author(s):

Chirathit Anusitviwat ◽

Khanin Iamthanaporn ◽

Pakjai Tuntarattanapong ◽

Boonsin Tangtrakulwanich ◽

Tippawan Liabsuetrakul

Keyword(s):

Regression Analysis ◽

Adverse Events ◽

Intramedullary Nailing ◽

Multivariate Logistic Regression Analysis ◽

Femoral Fractures ◽

Femoral Shaft ◽

Multivariate Regression Analysis ◽

Pathological Fractures ◽

Femoral Shaft Fractures ◽

Shaft Fractures

Abstract Background: Antegrade intramedullary nailing is indicated for treating metastatic pathological femoral shaft fractures. Although good functional outcomes could be obtained from internal fixation, postoperative adverse events have been reported in patients with pathological fractures and non-pathological fractures. Not only adverse events but also their consequences including, readmission and reoperation, need to be considered. Few studies have assessed the risk of postoperative adverse events, reoperation, and readmission without comparison. Therefore, this study aimed to compare the risk of in-hospital adverse events and consequences after discharge between patients with metastatic pathological and non-pathological femoral fractures undergoing intramedullary nailing.Methods: We conducted a retrospective study by extracting records from the Hospital Information System database. We accessed patients with pathological metastatic pathological and non-pathological femoral shaft fractures undergoing intramedullary nailing by the International Classification of Diseases code; from June 2006 to 2020. We then tracked the in-hospital medical and surgical adverse events postoperatively, along with the consequences after discharge. The in-hospital adverse events risk between the two groups of patients were analyzed and compared by multivariate logistic regression analysis.Results: Included patients consisted of 48 in pathological groups and 185 in non-pathological groups. Significantly higher rates of surgical and medical adverse events in patients with pathological fractures compared to patients with non-pathological fractures were observed. After adjusting for potential confounding factors in multivariate regression analysis, patients with pathological fractures had higher odds of both adverse surgical (adjusted OR 2.43, 95% CI 1.15 - 5.13) and medical adverse events (adjusted OR 2.81, 95% CI 1.13 - 7.03).Conclusions: Patients with metastatic pathological femoral shaft fractures undergoing intramedullary nailing were more likely to experience postoperative adverse events than patients with non-pathological fractures.

Download Full-text

The design of an “H” joystick for closed reduction and its application in segmental and comminuted femoral shaft fractures: an innovative technique

10.21203/rs.3.rs-26674/v2 ◽

2020 ◽

Author(s):

Zhaofeng Jia ◽

Shijin Wang ◽

Tinghui Xiao ◽

Wei Jiang ◽

Tianjian Zhou ◽

...

Keyword(s):

Intramedullary Nailing ◽

Closed Reduction ◽

Lateral Displacement ◽

Femoral Fractures ◽

Femoral Shaft ◽

Limb Length Discrepancy ◽

Bony Union ◽

Femoral Shaft Fractures ◽

Shaft Fractures ◽

Lateral Displacements

Abstract Background: Closed reduction and locked intramedullary nailing has become a common surgical method in the treatment of femoral shaft fractures. Overlap and rotation displacements can usually be corrected through the use of an orthopaedic traction table. However, lateral displacement and angulation persist. Methods: In this paper, we describe a joystick that can be used in the closed reduction of a fracture. It can correct lateral displacement and angulation and has the advantage of multi-direction reduction. The device described in this paper includes two parallel horizontal joysticks, one vertical main joystick and four assistant rods. Moreover, there are many specific spacing holes in the two parallel horizontal joysticks and a groove structure in the vertical main joystick. When the main “H” joystick is pressed, it can adjust lateral displacements and angulation because of the lever principle. The distance between parallel horizontal joysticks and assistant rods can be adjusted to the fracture position and body mass index of different patients. Results: The study participants consisted of 11 males and 5 females with a mean age of 31.0 years. All participants had good closed reduction and achieved bony union without any complications such as infection, nerve injury, nonunion, malunion and limb length discrepancy. By using an “H” joystick, closed femoral shaft fracture reduction and locked intramedullary nailing becomes simpler and faster. Conclusion: Based on the use of this instrument, we can easily and conveniently obtain the correct reduction situation, which leads to better surgical results. This device can be applied in the reduction of clinical femoral fractures and gradually extended to the reduction of other fractures.

Download Full-text

Comparison of Atypical and Osteoporotic Femoral Shaft Fractures in the Elderly: A Multicenter Study

Advances in Orthopedics ◽

10.1155/2018/1068053 ◽

2018 ◽

Vol 2018 ◽

pp. 1-5 ◽

Cited By ~ 2

Author(s):

Takanori Miura ◽

Hiroaki Kijima ◽

Noriyuki Ishikawa ◽

Toshihito Ebina ◽

Takayuki Tani ◽

...

Keyword(s):

Intramedullary Nailing ◽

Bone Healing ◽

Plate Fixation ◽

Femoral Fractures ◽

Femoral Shaft ◽

High Energy ◽

Healing Time ◽

Atypical Femoral Fractures ◽

Femoral Shaft Fractures ◽

Shaft Fractures

Background. In atypical femoral fractures, owing to the high rates of complications and delayed healing that accompany the plate fixation, the most favorable treatment is intramedullary nailing. Although there is insufficient evidence, plate fixation is chosen due to anterolateral bowing of the femur. This study compared the bone healing time and rates of complications in atypical femoral shaft fractures and osteoporotic femoral shaft fractures. Methods. We searched the medical records of 3 institutions in Japan for patients with femoral shaft fractures who visited between 1 January 2010 and 31 December 2015. We identified 65 patients and excluded 37 among these due to high-energy injuries or being younger than 65 years. Among the remaining patients, we identified 17 and 11 women with atypical (AFF group) and osteoporotic femoral shaft fractures (OP group), respectively. Results. In surgical method, there were differences in intramedullary nailing (94.1% versus 27.2%) (p<0.01). The mean bone healing time was 11.1 months versus 6.7 months in 2 groups (p<0.01). Iatrogenic femoral fractures during intramedullary nail insertion were observed in both groups, and reoperation was only seen in atypical femoral fractures treated with a plate fixation, but there was no difference in the rate of complications (23.5% versus 9.1%). Conclusions. In the atypical femoral fracture group, intramedullary nailing was more chosen, but the bone healing time was delayed and plate fixation cases needed reoperation. There was no significant difference in the rate of complications between the 2 groups.

Download Full-text

The design of an “H” joystick for closed reduction and its application in segmental and comminuted femoral shaft fractures: an innovative technique

10.21203/rs.3.rs-26674/v1 ◽

2020 ◽

Author(s):

Zhaofeng Jia ◽

Shijin Wang ◽

Tinghui Xiao ◽

Wei Jiang ◽

Tianjian Zhou ◽

...

Keyword(s):

Intramedullary Nailing ◽

Closed Reduction ◽

Lateral Displacement ◽

Femoral Fractures ◽

Femoral Shaft ◽

Limb Length Discrepancy ◽

Bony Union ◽

Femoral Shaft Fractures ◽

Shaft Fractures ◽

Lateral Displacements

Abstract Background Closed reduction and locked intramedullary nailing has become a common surgical method in the treatment of femoral shaft fractures. Overlap and rotation displacements can usually be corrected through the use of an orthopaedic traction table. However, lateral displacement and angulation persist. Methods In this paper, we describe a joystick that can be used in the closed reduction of a fracture. It can correct lateral displacement and angulation and has the advantage of multi-direction reduction. The device described in this paper includes two parallel horizontal joysticks, one vertical main joystick and four assistant rods. Moreover, there are many specific spacing holes in the two parallel horizontal joysticks and a groove structure in the vertical main joystick. When the main “H” joystick is pressed, it can adjust lateral displacements and angulation because of the lever principle. The distance between parallel horizontal joysticks and assistant rods can be adjusted to the fracture position and body mass index of different patients. Results The study participants consisted of 11 males and 5 females with a mean age of 31.0 years. All participants had good closed reduction and achieved bony union without any complications such as infection, nerve injury, nonunion, malunion and limb length discrepancy. By using an “H” joystick, closed femoral shaft fracture reduction and locked intramedullary nailing becomes simpler and faster. Conclusion Based on the use of this instrument, we can easily and conveniently obtain the correct reduction situation, which leads to better surgical results. This device can be applied in the reduction of clinical femoral fractures and gradually extended to the reduction of other fractures.

Download Full-text