scholarly journals A case report: anaphylaxis to cefazolin during renal transplant surgery

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Kaveh Hemati ◽  
Shelley Gierat ◽  
Garrett R. Roll ◽  
Odmara L. Barreto Chang
Keyword(s):  
Case Report ◽  
Renal Transplant ◽  
Case Reports ◽  
Graft Function ◽  
Intradermal Test ◽  
Case Presentation ◽  
Cadaveric Renal Transplant ◽  
First Case ◽  
Stage Renal Disease ◽  
End Stage

Abstract Background While there exist case reports of anaphylaxis occurring during renal transplant surgery, descriptions of continuing transplant surgery post-anaphylaxis have been scarce. Anaphylactic reactions that present solely with hypotension without pulmonary or mucocutaneous signs have yet to be described during renal transplant surgery. Case presentation Here we report a case of a 33-year-old female with end-stage renal disease who underwent cadaveric renal transplant. She developed anaphylaxis following the administration of cefazolin. Despite this reaction, the surgery was ultimately completed after patient stabilization, and the patient had excellent graft function postoperatively. The patient had an elevated tryptase at the time of the reaction and postoperative allergy testing revealed a positive intradermal test to cefazolin. Written informed consent was obtained from the patient for all procedures, studies, and publication of this case report. Conclusions This is the first case of a successful zero-mismatch cadaveric renal transplant following an anaphylactic reaction to cefazolin. Although anaphylaxis during transplant surgery typically warrants cancellation due to the hemodynamic effects that may lead to graft dysfunction, here we describe a case where surgery was continued following patient stabilization. The decision to proceed with surgery despite an intraoperative emergency along with the management and workup of intraoperative anaphylaxis are described, which can be beneficial for others who are presented with similar scenarios in the future.

scholarly journals Bilateral Tubulocystic Renal Cell Carcinomas in Diabetic End-Stage Renal Disease: First Case Report with Cytogenetic and Ultrastructural Studies

Rare Tumors ◽  
2013 ◽  
Vol 5 (4) ◽  
pp. 185-188 ◽  
Author(s):  
Max Xiangtian Kong ◽  
Christopher Hale ◽  
Antonio Subietas-Mayol ◽  
Peng Lee ◽  
Nicholas D. Cassai ◽  
...  
Keyword(s):  
Case Report ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Renal Cell ◽  
Renal Cell Carcinomas ◽  
Ultrastructural Studies ◽  
First Case ◽  
Stage Renal Disease ◽  
End Stage

Tumoral calcinosis-like lesion of the foot. A case report

1998 ◽  
Vol 88 (2) ◽  
pp. 87-91 ◽  
Author(s):  
GW Chalmers ◽  
WR Brown ◽  
JJ Stienstra
Keyword(s):  
Case Report ◽  
Magnetic Resonance ◽  
End Stage Renal Disease ◽  
Magnetic Resonance Images ◽  
Tumoral Calcinosis ◽  
Illustrative Case ◽  
Significant Morbidity ◽  
Case Presentation ◽  
Stage Renal Disease ◽  
End Stage

Tumoral calcinosis-like lesions of the foot are a pedal manifestation of end-stage renal disease. Although they are benign, they have the potential to cause significant morbidity because of their invasive nature. Following a brief description of tumoral calcinosis-like lesions, the authors provide an illustrative case presentation including radiographs, magnetic resonance images, surgical photographs, and histopathology.

scholarly journals Segmental Renal Ischemia following Transplantation of Horseshoe Kidney as Separate Allografts

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
J. T. Foster ◽  
P. E. Morrissey
Keyword(s):  
End Stage Renal Disease ◽  
Case Reports ◽  
Graft Function ◽  
Horseshoe Kidney ◽  
Deceased Donor ◽  
Successful Transplantation ◽  
Mere Presence ◽  
Technical Complication ◽  
Stage Renal Disease ◽  
End Stage

Introduction. Horseshoe kidney is a congenital anomaly that presents unique challenges for the transplant surgeon. The mere presence of horseshoe kidney should not preclude consideration for transplantation.Case Report. A 33-year-old women suffering from end-stage renal disease underwent deceased donor renal transplant with a divided horseshoe kidney. We present a postoperative complication and the technical strategy for transplant salvage. The patient currently has excellent graft function.Discussion. Horseshoe kidneys do present challenges for successful transplantation. Though case reports of successful transplantation are increasing, we present a technical complication and successful transplant salvage strategy. Technical descriptions in the literature of successful back-table preparation strategies should help more transplant surgeons to begin to utilize this resource.Conclusion. This study concludes that horseshoe kidneys can be successfully used for transplantation and provides a technical strategy to salvage the transplant after a unique complication associated with these donor kidneys.

scholarly journals Unsuccessful Treatment with Abatacept in Recurrent Focal Segmental Glomerulosclerosis after Kidney Transplantation

2017 ◽  
Vol 7 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Tilde Kristensen ◽  
Per Ivarsen ◽  
Johan Vestergaard Povlsen
Keyword(s):  
Renal Transplantation ◽  
Focal Segmental Glomerulosclerosis ◽  
Case Reports ◽  
Graft Function ◽  
Therapeutic Drug ◽  
Allograft Survival ◽  
Segmental Glomerulosclerosis ◽  
Unsuccessful Treatment ◽  
Stage Renal Disease ◽  
End Stage

Recurrence of focal segmental glomerulosclerosis (FSGS) after renal transplantation occurs in up to 20–50% of FSGS patients and is associated with inferior allograft survival. Treatment of both primary FSGS as well as recurrent FSGS after transplantation with plasma exchange and immunosuppression is often unsuccessful and remains a major challenge as the disease still leads to end-stage renal disease and decreased graft survival. Previous case reports have described patients with recurrent FSGS who were successfully treated with a B7-1 inhibitor (abatacept) inducing partial or complete remission. The rational basis for believing in abatacept as a new therapeutic drug for the treatment of FSGS is the study by Yu et al. [N Engl J Med 2013;369: 2416–2423] showing B7-1 in immunostainings of the podocytes. The authors speculated that B7-1 immunostaining of renal biopsies might identify a subgroup of patients who would benefit from abatacept treatment. We present a case with recurrent FSGS after renal transplantation. The patient was unsuccessfully treated with B7-1 inhibitors. Although the patient was treated with abatacept 10 mg/kg body weight twice, the proteinuria and decreased graft function remained unchanged, and he never reached remission.

Management of a ureteric stricture post ureteroileal anastomosis of a renal transplant

2021 ◽  
Vol 14 (6) ◽  
pp. e242763
Author(s):  
James P Ryan ◽  
Diarmuid Declan Sugrue ◽  
Niall F Davis ◽  
Ponnusamy Mohan
Keyword(s):  
Renal Transplant ◽  
Graft Function ◽  
Psoas Muscle ◽  
Team Approach ◽  
Tissue Mass ◽  
Urine Leak ◽  
The Right ◽  
Stage Renal Disease ◽  
End Stage ◽  
Living Related

A 58-year-old woman with a prior radical cystectomy and ileal conduit underwent a living-related donor renal transplant for end-stage renal disease secondary to autoimmune glomerulonephritis. She subsequently developed an ischaemic stricture of the transplant ureter. A successful ureteropyelostomy was performed with the native right ureter anastomosed to the pelvis of the renal transplant. She presented to the emergency department 18 months later feeling unwell and with raised inflammatory markers. Imaging demonstrated a large soft tissue mass over the right psoas muscle and hydronephrosis of the native right kidney. A nephrostomy and nephrostogram of the native right kidney diagnosed a urine leak from the native right kidney and she underwent an open right native nephrectomy. She recovered well postoperatively and continues to have excellent graft function. Renal transplantation in an abnormal urinary tract carries a high risk of complications. A multidisciplinary team approach is essential in offering the most appropriate treatment and ensuring good graft function is preserved.

End-stage renal disease in the course of urinary tract defects in Wolf–Hirschhorn syndrome – case report

2014 ◽  
Vol 1 (2) ◽  
pp. 229-236
Author(s):  
Katarzyna Jungiewicz ◽  
◽  
Irena Makulska ◽  
Anna Medyńska ◽  
Danuta Zwolińska ◽  
...  
Keyword(s):  
Case Report ◽  
Urinary Tract ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Delayed bowel perforation after instilling over warmed peritoneal dialysate

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Xueli Lai ◽  
Mingming Nie ◽  
Xiaodong Xu ◽  
Yuanjie Chen ◽  
Zhiyong Guo
Keyword(s):  
Peritoneal Dialysis ◽  
Bowel Perforation ◽  
Exploratory Laparotomy ◽  
Peritoneal Dialysis Patient ◽  
Case Presentation ◽  
Abdominal Organs ◽  
Home Based ◽  
Dialysis Solution ◽  
Stage Renal Disease ◽  
End Stage

Abstract Background Peritoneal dialysis (PD) is a safe and home-based treatment for end-stage renal disease (ESRD) patients. The direct thermal damage of abdominal organs is very rare. Case presentation We report a peritoneal dialysis patient presented abdominal pain and feculent effluent 3 weeks after he instilled hot dialysis solution. In spite of emergency exploratory laparotomy and active treatment, the patient died of septic shock. Biopsy revealed necrosis and perforation of the intestines. Conclusions Delayed bowel perforation by hot fluid is very rare. Standardized performance is of the first importance for peritoneal dialysis patients.

scholarly journals Providers’ View on the First Kidney Transplantation Center in Ethiopia: Experience From Past to Present

2021 ◽  
Vol 8 ◽  
pp. 233339282110183
Author(s):  
Tariku Shimels ◽  
Abrham Getachew ◽  
Mekdim Tadesse ◽  
Alison Thompson
Keyword(s):  
Kidney Transplantation ◽  
Renal Transplant ◽  
Health Care Providers ◽  
Study Data ◽  
Care Providers ◽  
Transplant Center ◽  
Transplantation Center ◽  
Stage Renal Disease ◽  
End Stage

Introduction: Transplantation is the optimal management for patients with end-stage renal disease. In Ethiopia, the first national kidney transplantation center was opened at St. Paul’s Hospital Millennium Medical College in September 2015. The aim of this study was to explore providers’ views and experiences of the past to present at this center. Methods: A qualitative study design was employed from 1st November to 15th December, 2019. To ensure that appropriate informants would provide rich study data, 8 health care providers and top management members were purposefully chosen for in-depth interviews. A maximum variation sampling method was considered to include a representative sample of informants. Interviews were digitally audio-recorded, and transcribed verbatim. Transcribed data was coded and analyzed using Qualitative Data Analysis (QDA) Minor Lite software and Microsoft-Excel. Result: The participants (5 males and 3 females) approached were from different departments of the renal transplant center, and the main hospital. Eight main themes and 18 sub-themes were generated initially from all interviews totaling to 109 index codes. Further evaluation and recoding retained 5 main themes, and 14 sub-themes. The main themes are; challenges experienced during and after launching the center, commitment, sympathy and satisfaction, outcomes of renal transplant, actions to improve the quality of service, and how the transplant center should operate. Providers claim that they discharge their responsibilities through proper commitment and compassion, paying no attention to incentive packages. They also explained that renal transplantation would have all the outcomes related to economic, humanistic and clinical facets. Conclusion and Recommendation: A multitude of challenges were faced during and after the establishment of the first renal transplant center in Ethiopia. Providers discharge their responsibility through a proper compassion for patients. Concerned stakeholders should actively collaborate to improve the quality of renal transplant services in the center.

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