scholarly journals Management challenges with brown tumor of primary hyperparathyroidism masked by severe vitamin D deficiency: a case report

2016 ◽  
Vol 10 (1) ◽  
Author(s):  
Marya Hussain ◽  
Montasir Hammam
Keyword(s):  
Vitamin D ◽  
Case Report ◽  
Primary Hyperparathyroidism ◽  
Vitamin D Deficiency ◽  
Brown Tumor ◽  
Severe Vitamin

scholarly journals Persistent Primary Hyperparathyroidism, Severe Vitamin D Deficiency, and Multiple Pathological Fractures

2016 ◽  
Vol 2016 ◽  
pp. 1-4
Author(s):  
Victoria Mendoza-Zubieta ◽  
Mauricio Carvallo-Venegas ◽  
Jorge Alberto Vargas-Castilla ◽  
Nicolás Ducoing-Sisto ◽  
Alfredo Alejandro Páramo-Lovera ◽  
...  
Keyword(s):  
Vitamin D ◽  
Primary Hyperparathyroidism ◽  
Vitamin D Deficiency ◽  
Bone Pain ◽  
Gamma Probe ◽  
Local Unit ◽  
Pathological Fractures ◽  
Severe Vitamin ◽  
Persistent Hyperparathyroidism ◽  
Skeletal Bone

Persistent primary hyperparathyroidism (PHPT) refers to the sustained hypercalcemia state detected within the first six months following parathyroidectomy. When it coexists with severe vitamin D deficiency, the effects on bone can be devastating. We report the case of a 56-year-old woman who was sent to this center because of persistent hyperparathyroidism. Her disease had over 3 years of evolution with nephrolithiasis and hip fracture. Parathyroidectomy was performed in her local unit; however, she continued with hypercalcemia, bone pain, and pathological fractures. On admission, the patient was bedridden with multiple deformations by fractures in thoracic and pelvic members. Blood pressure was 100/80, heart rate was 86 per minute, and body mass index was 19 kg/m2. Calcium was 14 mg/dL, parathormone 1648 pg/mL, phosphorus 2.3 mg/dL, creatinine 2.4 mg/dL, urea 59 mg/dL, alkaline phosphatase 1580 U/L, and vitamin D 4 ng/mL. She received parenteral treatment of hypercalcemia and replenishment of vitamin D. The second surgical exploration was radioguided by gamma probe. A retroesophageal adenoma of 4 cm was resected.Conclusion. Persistent hyperparathyroidism with severe vitamin D deficiency can cause catastrophic skeletal bone softening and fractures.

scholarly journals Hyperparathyroidism due to Parathyroid Adenoma with Co-existing Vitamin D Deficiency – A Case Report

2016 ◽  
Vol 5 (2) ◽  
pp. 104-106
Author(s):  
Md Raziur Rahman ◽  
Mohammad Abdul Hannan ◽  
Samira Rahat Afroze ◽  
Sultana Marufa Shefin ◽  
Muhammad Abdur Rahim ◽  
...  
Keyword(s):  
Vitamin D ◽  
Case Report ◽  
Primary Hyperparathyroidism ◽  
Secondary Hyperparathyroidism ◽  
Parathyroid Adenoma ◽  
Vitamin D Deficiency ◽  
Musculoskeletal Symptoms ◽  
Asymptomatic Hyperparathyroidism ◽  
Routine Investigations

Primary hyperparathyroidism is often asymptomatic, may be detected during routine investigations or may present with features of hypercalcaemia. Vitamin D deficiency causing secondary hyperparathyroidism presents with musculoskeletal symptoms. Studies have shown an association between primary hyperparathyroidism and vitamin D deficiency. It has also been observed that when co-exist, these two conditions contribute to each other’s disease presentation and severity. This case report depicts initial asymptomatic hyperparathyroidism developing symptoms due to co-existing parathyroid adenoma and vitamin D deficiency in a 26-year-old muslim Bangladeshi female who responded well to adequate pre, per and post parathyroidectomy medical managementBirdem Med J 2015; 5(2): 104-106

Metacarpal Brown Tumor in Secondary Hyperparathyroidism Due to Vitamin-D Deficiency: A Case Report

2005 ◽  
Vol os-87 (6) ◽  
pp. 1363-1366 ◽  
Author(s):  
E. Erturk ◽  
M. Keskin ◽  
C. Ersoy ◽  
T. Kaleli ◽  
S. Imamoglu ◽  
...  
Keyword(s):  
Vitamin D ◽  
Case Report ◽  
Secondary Hyperparathyroidism ◽  
Vitamin D Deficiency ◽  
Brown Tumor
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