scholarly journals Cutaneous metastasis of cecum cancer with MSI-high and BRAFV600E mutation: a case report

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Kosuke Yunoki ◽  
Takuya Yano ◽  
Masanori Yoshimitsu ◽  
Ko Oshita ◽  
Tetsushi Kubota ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Rare Case ◽  
Distant Metastases ◽  
Excisional Biopsy ◽  
Cutaneous Metastasis ◽  
Pathological Examination ◽  
Brafv600e Mutation ◽  
Computed Tomography Scan ◽  
Cecum Cancer ◽  
Tomography Scan

Abstract Background Cutaneous metastases of colorectal cancer (CRC) are rare, occurring in 0.7% to 5% of cancer patients. Furthermore, the molecular subtypes of cutaneous metastasis of CRC are unclear. Here, we present a rare case of cutaneous metastasis of high-frequency microsatellite instability (MSI-high)/BRAFV600E-mutant cecum cancer. Case presentation A 77-year-old woman presented at the outpatient clinic with a subcutaneous mass on her left back. An excisional biopsy was performed and metastatic cutaneous adenocarcinoma was diagnosed. A computed tomography scan of the thorax and abdomen showed thickening of the cecum wall, the presence of pericolic lymph nodes, multiple masses in the liver, and a single nodule in the right lung. Right colectomy with D2 lymphadenectomy and functional end-to-end anastomosis was performed because of the almost-complete intestinal obstruction. The expression of KRAS wild type, BRAFV600E mutation, and MSI-high was detected in the cecum cancer using molecular pathological examination. She received chemotherapy with XELOX + BEV regimen (capecitabine + oxaliplatin + bevacizumab). After four administrations, a computed tomography scan showed reduction of distant metastases, which suggested partial response. Conclusions We encountered a rare case of cutaneous metastasis of MSI-high and BRAFV600E-mutant cecum cancer. In the future, it will be necessary to accumulate more cases to identify clinical features and more effective treatments for CRCs with cutaneous metastasis.

scholarly journals Cutaneous Metastasis as the Presenting Sign of Urothelial Carcinoma

2020 ◽  
Vol 78 (3) ◽  
pp. 255-259
Author(s):  
Tânia Rita Moreno de Oliveira Fernandes ◽  
Ricardo Santana de Lima ◽  
Ana Kívia Silva Matias ◽  
Leonardo Pereira de Souza Alves ◽  
Marcus Vinícius Solano Ferreira de Souza
Keyword(s):  
Computed Tomography ◽  
Skin Biopsy ◽  
Urothelial Carcinoma ◽  
Rare Case ◽  
Transitional Cell ◽  
Cutaneous Metastasis ◽  
Computed Tomography Scan ◽  
Internal Organs ◽  
Cutaneous Metastases ◽  
Tomography Scan

Cutaneous metastases of visceral neoplasms are rare conditions, and urothelial or transitional cell carcinomas are responsible for less than 1% of cases. We report the case of a 50-year-old male patient who progressively developed multiple cutaneous nodules on his head, abdomen, axilla, and groin, some with ulceration. Skin biopsy and immunohistochemistry were consistent with cutaneous metastasis of urothelial carcinoma. Computed tomography scan revealed generalized metastasis in internal organs. In this rare case, cutaneous metastases were the presenting sign of the disease and, as reported, a sign of bad prognosis.

scholarly journals Retroauricular Emphysema as a Late Complication After Bonebridge Implantation: Case Report

2021 ◽  
pp. 014556132110002
Author(s):  
Soňa Šikolová ◽  
Dagmar Hošnová ◽  
Klára Perceová ◽  
Michal Bartoš ◽  
Vít Kruntorád ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Case Report ◽  
Postoperative Complications ◽  
Rare Case ◽  
Late Complication ◽  
Bone Conduction ◽  
Computed Tomography Scan ◽  
Artificial Opening ◽  
Low Incidence ◽  
Tomography Scan

Bonebridge (BB) is the first active implantation system for bone conduction that is placed fully under the skin. Experience suggests that BB is characterized by low incidence of postoperative complications. This case report presents a rare case of a 16-year-old girl with incidence of emphysema occurring over the implant 1 year after operation. We performed a computed tomography scan that showed pockets of gas above the floating mass transducer so we provided the revision surgery and sealed the artificial opening with fat from the earlobe and fibrin glue. Since that time, no air has collected in the retroauricular area and the implant has been fully functional.

scholarly journals Voluminous Intrapericardial Lipoma Mimicking Pericardial Effusion

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Fabíola Prado de Morais ◽  
Noah Romero Nakajima ◽  
Olívia Félix Marconi Andalécio ◽  
Pedro de Santana Prudente ◽  
Guilherme Emílio Ferreira ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Pericardial Effusion ◽  
Signs And Symptoms ◽  
Tumor Location ◽  
Pathological Examination ◽  
Computed Tomography Scan ◽  
Radiologic Imaging ◽  
Heart Tumors ◽  
Tomography Scan

Lipomas are rare primary heart tumors and may involve the endocardium, myocardium, or pericardium. Signs and symptoms depend on the tumor location and size. The intrapericardial lipoma we report has massive dimensions and mimics a pericardial effusion. A 38-year-old male complained of dyspnea and precordial pain. On physical examination, heart sounds were diminished. The patient had received extensive medication for a clinically suspected pericardial effusion due to heart failure. A voluminous mass resembling fat within the pericardial sac was revealed by transesophageal echocardiography and a computed tomography scan. The tumor was removed successfully by a subxiphoid surgical approach. The diagnosis of a 635 gram intrapericardial lipoma was confirmed by pathological examination. After surgery, the patient recovered well and was completely asymptomatic at a follow-up at 90 days. No medications were being taken since. The diagnosis of a pericardial effusion should be secured by imaging exams to avoid unnecessary medications. Cardiac lipomas can be readily recognized by their typical features on radiologic imaging. The surgical pathology examination confirms the diagnosis and rules out malignancy criteria.

scholarly journals Mucinous adenocarcinoma arising in an anorectal fistula

Medicina ◽  
2008 ◽  
Vol 45 (4) ◽  
pp. 286 ◽  
Author(s):  
Linas Venclauskas ◽  
Žilvinas Saladžinskas ◽  
Algimantas Tamelis ◽  
Darius Pranys ◽  
Dainius Pavalkis
Keyword(s):  
Computed Tomography ◽  
Soft Tissue ◽  
Histological Examination ◽  
Abdominoperineal Resection ◽  
Mucinous Adenocarcinoma ◽  
Rare Case ◽  
Anorectal Fistula ◽  
Computed Tomography Scan ◽  
Perineal Abscess ◽  
Tomography Scan

Mucinous adenocarcinoma in association with chronic anal fistula is a rare case in clinical practice. The aim of this article was to report a rare case of anal gland mucinous adenocarcinoma in a patient who was treated in the Hospital of Kaunas University of Medicine. Case report. A 70-year-old male was treated for anorectal fistula in the surgical department. Four operations were performed for perineal abscess during the period of 15 years. During the period of 15 years, the patient complained of purulent secretion from the perineal abscess. After the last operation, anorectal fistula developed. Multiple biopsies and scrapings of the fistulous track were taken for histological examination. Histological examination revealed mucinous adenocarcinoma, G2. Subsequently, the patient underwent endoanal ultrasound, computed tomography scan, and colonoscopy. The computed tomography scan did not show pathology in the abdomen, but showed soft tissue induration at the site of anorectal fistula. Colonoscopy investigation did not show any pathology in the rectum and bowels. Endoanal ultrasound findings showed soft tissue induration at the site of anorectal fistula, no tumor in the rectum wall. The patient underwent abdominoperineal resection. Histological examination after abdominoperineal resection revealed anal duct mucinous adenocarcinoma pT2 N0 L0 V0 R0, G2. Metastases to the mesenteric lymph nodes were not detected. On the eight day after abdominoperineal resection, the patient was discharged from the hospital for follow-up. Summary. Mucinous adenocarcinoma in anorectal fistula is a rare condition. If surgical treatment for perineal abscess or anorectal fistula is not successful for a long time, mucinous adenocarcinoma should be suspected.

A Rare Case of Isolated Atrial Myocarditis Causing Death With no Post Mortem Computed Tomography Scan Correlation

2018 ◽  
Vol 39 (2) ◽  
pp. 123-125 ◽  
Author(s):  
Rexson Tse ◽  
Jack Garland ◽  
Kilak Kesha ◽  
Yvonne Triggs ◽  
Lucy Modahl ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Rare Case ◽  
Post Mortem ◽  
Computed Tomography Scan ◽  
Tomography Scan

A rare case of spontaneous thyroid cyst haemorrhage

2012 ◽  
Vol 126 (9) ◽  
pp. 960-962 ◽  
Author(s):  
C C Chan ◽  
A Awobem ◽  
C Binns ◽  
P Jassar
Keyword(s):  
Computed Tomography ◽  
Case Report ◽  
Rare Case ◽  
Needle Aspiration ◽  
Airway Compromise ◽  
Computed Tomography Scan ◽  
Steroid Injections ◽  
Intravenous Steroid ◽  
Thyroid Cyst ◽  
Tomography Scan

AbstractBackground:We report a case of hypopharyngeal swelling secondary to a spontaneous thyroid cyst haemorrhage. Haemorrhage is a known complication of thyroid cysts, and usually presents as external swelling and localised pain.Case report:A 93-year-old woman developed hypopharyngeal swelling, dysphagia and odynophagia. A computed tomography scan was consistent with thyroid cyst haemorrhage. The patient was treated with needle aspiration and intravenous steroid injections, with full recovery at thyroid clinic review.Conclusion:To our best knowledge, there has been no previous report of a hypopharyngeal swelling occurring secondary to spontaneous thyroid cyst haemorrhage. Our case is unusual because of the risk of airway compromise at the level of the hypopharynx, secondary to thyroid cyst haemorrhage.

scholarly journals A rare case of pedunculated bronchial hemangioma

2016 ◽  
Vol 70 (4) ◽  
Author(s):  
M. Bellia ◽  
A. Lo Casto ◽  
F. Guddo ◽  
M. Midiri ◽  
S. Regio ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Rare Case ◽  
Fiberoptic Bronchoscopy ◽  
Capillary Hemangioma ◽  
Productive Cough ◽  
Endoscopic Removal ◽  
Computed Tomography Scan ◽  
Vascular Neoplasm ◽  
Tridimensional Reconstruction ◽  
Tomography Scan

We describe a rare case of pedunculated endobronchial hemangioma observed in a 60 years old patient complaining of chronic productive cough and accessional dyspnea which had been progressively worsening over 20 years. The lesion was first noticed at fiberoptic bronchoscopy; then computed tomography scan was performed and integrated with tridimensional reconstruction techniques. Pathology showed the picture of a vascular neoplasm, compatible with capillary hemangioma. The lesion was submitted to laser-assisted endoscopic removal in order to relieve the obstruction, leading to remission of symptoms.

scholarly journals Intralingual Mucous Extravasation Cyst: An Uncommon Lingual Cyst

2019 ◽  
Vol 98 (5) ◽  
pp. E21-E23
Author(s):  
Evelyne S. Diom ◽  
Johannes J. Fagan ◽  
Ellen Bolding
Keyword(s):  
Computed Tomography ◽  
Differential Diagnosis ◽  
Histological Examination ◽  
Rare Case ◽  
Cystic Lesion ◽  
Standard Of Care ◽  
Ventral Surface ◽  
Computed Tomography Scan ◽  
Diagnostic Features ◽  
Tomography Scan

Objective: We report a rare case of an intralingual ranula. The differential diagnosis, etiology, diagnostic features, and management are discussed. Case Report: An 18-year-old man presented with a mass that extended along the ventral surface of the tongue and up to the tip. The computed tomography scan clearly defined the extent of a cystic lesion. The pathologic diagnosis of an intralingual ranula was made. Conclusion: Lingual cysts have a varied etiology. Diagnosis hinges on histological examination of the cyst wall. Conservative resection and histological examination is the standard of care.

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