Efficacy and safety of acamprosate in the treatment of detoxified alcohol-dependent patients
1997 ◽
Vol 171
(1)
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pp. 73-77
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Keyword(s):
BackgroundAcamprosate is a newly registered drug that appears to reduce alcohol-drinking in both animal models and clinical conditions.MethodIn order to assess the efficacy and safety of the drug in the treatment of detoxified alcoholics, we performed a 90-day double-blind trial comparing two dosages of acamprosate (1332 mg/day and 1998 mg/day).ResultsFor all efficacy parameters, acamprosate appeared to be significantly superior to placebo, with a trend towards a better effect at the higher dosage. Furthermore, acamprosate appeared to be extremely safe.ConclusionThis study confirms that acamprosate could be an interesting adjuvant for maintaining abstinence in detoxified alcoholics.
2019 ◽
Vol 12
(1)
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pp. 48-54
2011 ◽
Vol 5
(S1)
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pp. 269-270
2012 ◽
Vol 2012
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pp. 111-113
Keyword(s):
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2003 ◽
Vol 160
(8)
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pp. 1396-1404
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2018 ◽
Vol 138
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pp. 253-261
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2003 ◽
Vol 17
(3)
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pp. 343-351
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Keyword(s):
2008 ◽
Vol 26
(3)
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pp. 589-599
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Keyword(s):