Diagnostic stability of first-episode psychosis

1999 ◽  
Vol 175 (6) ◽  
pp. 537-543 ◽  
Author(s):  
Shazad Amin ◽  
Swaran P. Singh ◽  
John Brewin ◽  
Peter B. Jones ◽  
Ian Medley ◽  
...  
Keyword(s):  
Temporal Stability ◽  
Bipolar Disorders ◽  
High Specificity ◽  
First Episode Psychosis ◽  
First Episode ◽  
Predictive Values ◽  
Diagnostic Stability ◽  
Episode Psychosis ◽  
Icd 10 ◽  
Low Sensitivity

BackgroundThe temporal stability of a diagnosis is one measure of its predictive validity.AimsTo measure diagnostic stability in first-episode psychosis using ICD–10 and DSM–III–R.MethodBetween 1992 and 1994 we ascertained a cohort of persons with first-episode psychosis (n=168), assigning to each a consensus diagnosis. At three-year follow-up, longitudinal consensus diagnoses, blind to onset diagnoses, were made. Stability was measured by the positive predictive values (PPVs) of onset diagnoses. For onset schizophrenia, we also calculated sensitivity, specificity and concordance (κ).ResultsFirst-episode ICD–10 and DSM–III–R schizophrenia had a PPV of over 80% at three years. Over one-third of cases with ICD–10 F20 schizophrenia at three years had non-schizophrenia diagnoses at onset. Manic psychoses showed the highest PPV (91%). For onset schizophrenia, both systems had high specificity (ICD–10: 89; DSM–III–R: 93%), but low sensitivity (ICD–10: 64%; DSM–III–R: 51%) and moderate concordance (ICD–10: 0.54; DSM–III–R: 0.46).ConclusionsBipolar disorders and schizophrenia showed the highest stability. DSM–III–R schizophrenia did not have greater stability than ICD–10 schizophrenia.

First-Episode Psychosis: Diagnostic Stability over One and Two Years

2008 ◽  
Vol 41 (5) ◽  
pp. 322-329 ◽  
Author(s):  
Ulrik Haahr ◽  
Svein Friis ◽  
Tor K. Larsen ◽  
Ingrid Melle ◽  
Jan Olav Johannessen ◽  
...  
Keyword(s):  
First Episode Psychosis ◽  
First Episode ◽  
Diagnostic Stability ◽  
Episode Psychosis

Diagnostic stability over one year in first-episode psychosis

2006 ◽  
Vol 86 (1-3) ◽  
pp. 71-75 ◽  
Author(s):  
Jean Addington ◽  
Ana Chaves ◽  
Donald Addington
Keyword(s):  
First Episode Psychosis ◽  
First Episode ◽  
Diagnostic Stability ◽  
Episode Psychosis ◽  
One Year

Five-year stability of ICD-10 diagnoses among Chinese patients presented with first-episode psychosis in Hong Kong

2009 ◽  
Vol 115 (2-3) ◽  
pp. 351-357 ◽  
Author(s):  
Wing Chung Chang ◽  
Shirley Lai Kwan Pang ◽  
Dicky Wai Sau Chung ◽  
Sandra Sau Man Chan
Keyword(s):  
Hong Kong ◽  
First Episode Psychosis ◽  
Chinese Patients ◽  
First Episode ◽  
Episode Psychosis ◽  
Icd 10

scholarly journals Acute and transient psychotic disorders: precursors, epidemiology, course and outcome

2004 ◽  
Vol 185 (6) ◽  
pp. 452-459 ◽  
Author(s):  
Swaran P. Singh ◽  
Tom Burns ◽  
Shazad Amin ◽  
Peter B. Jones ◽  
Glynn Harrison
Keyword(s):  
Psychotic Disorders ◽  
First Episode Psychosis ◽  
Acute Onset ◽  
Favourable Outcome ◽  
First Episode ◽  
Affective Psychosis ◽  
Episode Psychosis ◽  
Icd 10 ◽  
Premorbid Functioning ◽  
Better Than

BackgroundICD–10 has introduced the diagnostic group acute and transient psychotic disorders (ATPDs; F23). Aims To validate the nosological distinctiveness of ICD–10 ATPDs by following up an inception cohort with first-episode psychosis. Method All patients with first-episode psychosis identified in Nottingham between 1992 and 1994 and diagnosed using ICD–10 criteria were reassessed 3 years later. ATPD outcomes were compared with schizophrenia and affective psychosis. Multivariate analyses were conducted to determine whether acute onset and early remission predicted favourable 3-year outcome in first-episode psychosis. Results Of 168 cases of first-episode psychosis, 32 (19%) received an intake diagnosis of ATPD. The diagnosis of ATPD was stable in women over 3 years, but not in men. Outcomes in ATPD were better than in schizophrenia and similar to affective psychosis. In non-affective psychoses, favourable outcomes were a function of gender and premorbid functioning rather than acute onset and early remission. Conclusions The ICD–10 criteria for ATPDs identify a diagnostically unstable group of disorders. Acute onset and early remission do not independently predict favourable outcome over 3 years in first-episode psychosis.

Diagnostic Stability and Clinical Characteristics in First-episode Psychosis

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
D. Berge ◽  
A. Mane ◽  
P. Salgado ◽  
O. Vilarroya ◽  
A. Merino ◽  
...  
Keyword(s):  
First Episode Psychosis ◽  
First Episode ◽  
Schizophreniform Disorder ◽  
Schizophrenia Spectrum Disorders ◽  
Diagnostic Stability ◽  
Episode Psychosis ◽  
Hospitalization Period ◽  
Wide Variability ◽  
One Year

Introduction:Diagnostic stability in first-episode psychosis shows a wide variability between studies. Amini and cols reported a 50% rate of patients schizophreniform disorder shifting to schizophrenia during the first 12 months period. We report the preliminary follow-up results of our recently ongoing first- episode psychosis unit.Methods:Forty-six patients admitted for a first-episode psichosis to our Inpatient Psychiatric Unit from January 2006 to January 2008 were recruited. Clinical and socio-demographic characteristics were registered during admission period and during the follow-up period.Results:At admission 52% of the first-episode subjects had a diagnosis of psychosis NOS and 32% a schizophreniform disorder diagnosis. after discharge, most of the patients (72%) had a diagnosis of schizophreniform disorder, 16% psychosis NOS and 8% brief psychotic disorder. Six months later, half of the followed-up patients had a schizophreniform disorder diagnosis, and 23% had a diagnosis of schizophrenia. 30% of the patients were drop-outs, mainly referred to other out-patient services. Patients shifting to schizophrenia were younger, predominantly male (75% vs 50% in non-schizophrenia shift), had a lower proportion of university studies and presented a longer hospitalization period at admission. No differences in familial history of psychosis and cannabis use were found. after one-year follow-up period, 50% preserved a schizophreniform disorder diagnosis and 30% were diagnosed as schizophrenia.Conclusions:Schizophrenia spectrum disorders have a high stability in first-episode psychosis during first year follow-up. as in previous studies, male gender is one of the factors that best predicts the shift to schizophrenia.

scholarly journals S217. SELF-DISTURBANCES AND DIAGNOSTIC STABILITY IN FIRST EPISODE PSYCHOSIS: A SEVEN YEAR FOLLOW-UP STUDY

2018 ◽  
Vol 44 (suppl_1) ◽  
pp. S410-S410
Author(s):  
Ingrid Svendsen ◽  
Merete Øie ◽  
Paul Møller ◽  
Barnaby Nelson ◽  
Ingrid Melle ◽  
...  
Keyword(s):  
First Episode Psychosis ◽  
First Episode ◽  
Diagnostic Stability ◽  
Follow Up Study ◽  
Episode Psychosis

The diagnostic stability of ICD-10 psychiatric diagnoses in clinical practice

1997 ◽  
Vol 12 (3) ◽  
pp. 136-139 ◽  
Author(s):  
TK Daradkeh ◽  
OEF El-Rufaie ◽  
YO Younis ◽  
R Ghubash
Keyword(s):  
Psychiatric Disorders ◽  
United Arab Emirates ◽  
Depressive Disorders ◽  
Psychotic Disorders ◽  
Somatoform Disorders ◽  
Temporal Stability ◽  
Diagnostic System ◽  
Bipolar Disorders ◽  
Diagnostic Stability ◽  
Icd 10

SummaryThis study examines the stability of ICD-10 diagnoses of patients admitted to Al Ain (United Arab Emirates) inpatients psychiatric unit during the period from November 1993 to August 1995. Diagnostic stability is a measure of the degree to which diagnoses remained unchanged at a later hospital admission. One hundred and seven patients were admitted more than once during this period, accounting for 168 readmissions. High levels of diagnostic stability were found for ICD-10 Fl-psychiatric disorders (100%), F2-schizophrenia (87%), F3-bipolar disorders (87%) and F3-depressive disorders (73%). A poor level of stability was found for patients with neurotic, stress related and adjustment disorders (F4), ranging from zero for somatoform disorders to 50% for generalized anxiety and panic disorders. Poor levels of stability were also found for other psychoses (excluding schizophrenia and affective psychoses) and personality disorders. We conclude that the introduction of ICD-10 as a formal diagnostic system has greatly improved the temporal stability of the most commonly encountered psychiatric disorders (ICD-10 Fl to F3 disorders), confirming the construct validity of those psychiatric disorders. Further investigations are required to evaluate the diagnostic stability of neurotic and other psychotic disorders.

scholarly journals Social anxiety disorder in first-episode psychosis: incidence, phenomenology and relationship with paranoia

2009 ◽  
Vol 195 (3) ◽  
pp. 234-241 ◽  
Author(s):  
Maria Michail ◽  
Max Birchwood
Keyword(s):  
Anxiety Disorder ◽  
Social Anxiety ◽  
Social Anxiety Disorder ◽  
First Episode Psychosis ◽  
Psychotic Symptoms ◽  
First Episode ◽  
Socially Anxious ◽  
Causal Pathway ◽  
Episode Psychosis ◽  
Icd 10

BackgroundSocial anxiety disorder constitutes a significant problem for people with psychosis. It is unclear whether this is a by-product of persecutory thinking.AimsTo compare the phenomenology of social anxiety disorder in first-episode psychosis with that in a group without psychosis. The relationship between social anxiety and psychosis symptoms was investigated.MethodA sample of people with first-episode psychosis (FEP group) was compared with a sample with social anxiety disorder without psychosis (SaD group).ResultsOf the individuals in the FEP group (n = 80) 25% were diagnosed with an ICD–10 social anxiety disorder (FEP/SaD group); a further 11.6% reported severe difficulties in social encounters. The FEP/SaD and SaD groups reported comparable levels of social anxiety, autonomic symptoms, avoidance and depression. Social anxiety in psychosis was not related to the positive symptoms of the Positive and Negative Syndrome Scale (PANSS) including suspiciousness/persecution. However, a significantly greater percentage of socially anxious v. non-socially anxious individuals with psychosis expressed perceived threat from persecutors, although this did not affect the severity of social anxiety within the FEP/SaD group. The majority of those in the FEP/SaD group did not have concurrent persecutory delusions.ConclusionsSocial anxiety is a significant comorbidity in first-episode psychosis. It is not simply an epiphenomenon of psychotic symptoms and clinical paranoia, and it has more than one causal pathway. For a subgroup of socially anxious people with psychosis, anticipated harm is present and the processes that underlie its relationship with social anxiety warrant further investigation.

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