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A phase I study of CS-1008 (humanized monoclonal antibody targeting death receptor 5 or DR5), administered weekly to patients with advanced solid tumors or lymphomas
Journal of Clinical Oncology
◽
10.1200/jco.2008.26.15_suppl.3537
◽
2008
◽
Vol 26
(15_suppl)
◽
pp. 3537-3537
◽
Cited By ~ 18
Author(s):
M. N. Saleh
◽
I. Percent
◽
T. E. Wood
◽
J. Posey
◽
J. Shah
◽
...
Keyword(s):
Monoclonal Antibody
◽
Phase I
◽
Solid Tumors
◽
Phase I Study
◽
Death Receptor
◽
Advanced Solid Tumors
◽
Death Receptor 5
◽
Humanized Monoclonal Antibody
◽
Antibody Targeting
Download Full-text
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Phase I Study of Enavatuzumab, a First-in-Class Humanized Monoclonal Antibody Targeting the TWEAK Receptor, in Patients with Advanced Solid Tumors
Molecular Cancer Therapeutics
◽
10.1158/1535-7163.mct-17-0330
◽
2017
◽
Vol 17
(1)
◽
pp. 215-221
◽
Cited By ~ 7
Author(s):
Elaine T. Lam
◽
S. Gail Eckhardt
◽
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Antonio Jimeno
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...
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Monoclonal Antibody
◽
Phase I
◽
Solid Tumors
◽
Phase I Study
◽
Advanced Solid Tumors
◽
Humanized Monoclonal Antibody
◽
Antibody Targeting
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415 A phase I study evaluating the safety profile and pharmacokinetics of CS-1008 (Tigatuzumab), humanized monoclonal antibody targeting death receptor 5 (DR5), in Japanese patients with advanced solid tumours
European Journal of Cancer Supplements
◽
10.1016/s1359-6349(10)72122-4
◽
2010
◽
Vol 8
(7)
◽
pp. 132
Author(s):
H. Nokihara
◽
N. Yamamoto
◽
Y. Yamada
◽
H. Asahina
◽
T. Shibata
◽
...
Keyword(s):
Monoclonal Antibody
◽
Phase I
◽
Safety Profile
◽
Phase I Study
◽
Death Receptor
◽
Japanese Patients
◽
Solid Tumours
◽
Death Receptor 5
◽
Humanized Monoclonal Antibody
◽
Antibody Targeting
Download Full-text
Phase I Trial of Weekly Tigatuzumab, an Agonistic Humanized Monoclonal Antibody Targeting Death Receptor 5 (DR5)
Cancer Biotherapy & Radiopharmaceuticals
◽
10.1089/cbr.2009.0673
◽
2010
◽
Vol 25
(1)
◽
pp. 13-19
◽
Cited By ~ 103
Author(s):
Andres Forero-Torres
◽
Jatin Shah
◽
Tina Wood
◽
James Posey
◽
Ronda Carlisle
◽
...
Keyword(s):
Monoclonal Antibody
◽
Phase I
◽
Phase I Trial
◽
Death Receptor
◽
Death Receptor 5
◽
Humanized Monoclonal Antibody
◽
Antibody Targeting
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A phase I study of ontuxizumab, a humanized monoclonal antibody targeting endosialin, in Japanese patients with solid tumors
Investigational New Drugs
◽
10.1007/s10637-018-0713-7
◽
2019
◽
Vol 37
(5)
◽
pp. 1061-1074
◽
Cited By ~ 1
Author(s):
Toshihiko Doi
◽
Takeshi Aramaki
◽
Hirofumi Yasui
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Kei Muro
◽
Masafumi Ikeda
◽
...
Keyword(s):
Monoclonal Antibody
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Phase I
◽
Solid Tumors
◽
Phase I Study
◽
Japanese Patients
◽
Humanized Monoclonal Antibody
◽
Antibody Targeting
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A phase I study of sonepcizumab (S), a humanized monoclonal antibody to sphingosine-1-phosphate (S1P), in patients with advanced solid tumors.
Journal of Clinical Oncology
◽
10.1200/jco.2010.28.15_suppl.2560
◽
2010
◽
Vol 28
(15_suppl)
◽
pp. 2560-2560
◽
Cited By ~ 8
Author(s):
M. S. Gordon
◽
R. Just
◽
L. S. Rosen
◽
A. Dorr
Keyword(s):
Monoclonal Antibody
◽
Phase I
◽
Solid Tumors
◽
Phase I Study
◽
Advanced Solid Tumors
◽
Humanized Monoclonal Antibody
◽
Sphingosine 1 Phosphate
Download Full-text
Phase I study of humanized monoclonal antibody AVE1642 directed against the type 1 insulin-like growth factor receptor (IGF-1R), administered in combination with anticancer therapies to patients with advanced solid tumors
Annals of Oncology
◽
10.1093/annonc/mds511
◽
2013
◽
Vol 24
(3)
◽
pp. 784-791
◽
Cited By ~ 32
Author(s):
V.M. Macaulay
◽
M.R. Middleton
◽
A.S. Protheroe
◽
A. Tolcher
◽
V. Dieras
◽
...
Keyword(s):
Monoclonal Antibody
◽
Growth Factor
◽
Phase I
◽
Solid Tumors
◽
Phase I Study
◽
Growth Factor Receptor
◽
Advanced Solid Tumors
◽
Insulin Like Growth Factor
◽
Humanized Monoclonal Antibody
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404 Phase I study of MEDI-575, a fully human monoclonal antibody targeting PDGFR-alpha in subjects with advanced solid tumors
European Journal of Cancer Supplements
◽
10.1016/s1359-6349(10)72111-x
◽
2010
◽
Vol 8
(7)
◽
pp. 128
◽
Cited By ~ 1
Author(s):
R. Lechleider
◽
C. Becerra
◽
M. Liang
◽
R. Narwal
◽
L. Shi
◽
...
Keyword(s):
Monoclonal Antibody
◽
Phase I
◽
Solid Tumors
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Phase I Study
◽
Human Monoclonal Antibody
◽
Advanced Solid Tumors
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Antibody Targeting
◽
Pdgfr Alpha
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Phase I Study of U3-1287, A Human Monoclonal Antibody Targeting Her3, in Japanese Patients with Advanced Solid Tumors
Annals of Oncology
◽
10.1016/s0923-7534(20)33026-x
◽
2012
◽
Vol 23
◽
pp. ix161-ix162
Author(s):
H. Wakui
◽
N. Yamamoto
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S. Nakamichi
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Y. Tamura
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H. Nokihara
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Keyword(s):
Monoclonal Antibody
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Phase I
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Solid Tumors
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Phase I Study
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Human Monoclonal Antibody
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Japanese Patients
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Advanced Solid Tumors
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Antibody Targeting
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Abstract C18: A phase I study of enavatuzumab (PDL192, ABT-361), a first-in-class human monoclonal antibody targeting TWEAK (tumor necrosis factor-like inducer of apoptosis) receptor, in patients (Pts) with advanced solid tumors.
10.1158/1535-7163.targ-11-c18
◽
2011
◽
Cited By ~ 1
Author(s):
Elaine T. Lam
◽
S. Gail Eckhardt
◽
Wells Messersmith
◽
Antonio Jimeno
◽
Cindy L. O'Bryant
◽
...
Keyword(s):
Monoclonal Antibody
◽
Tumor Necrosis Factor
◽
Phase I
◽
Solid Tumors
◽
Phase I Study
◽
Tumor Necrosis
◽
Human Monoclonal Antibody
◽
Advanced Solid Tumors
◽
Antibody Targeting
◽
Necrosis Factor
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Phase I study of every 2- or 3-week dosing of ramucirumab, a human immunoglobulin G1 monoclonal antibody targeting the vascular endothelial growth factor receptor-2 in patients with advanced solid tumors
Annals of Oncology
◽
10.1093/annonc/mdv144
◽
2015
◽
Vol 26
(6)
◽
pp. 1230-1237
◽
Cited By ~ 42
Author(s):
E.G. Chiorean
◽
H.I. Hurwitz
◽
R.B. Cohen
◽
J.D. Schwartz
◽
R.P. Dalal
◽
...
Keyword(s):
Monoclonal Antibody
◽
Vascular Endothelial Growth Factor
◽
Growth Factor
◽
Phase I
◽
Solid Tumors
◽
Phase I Study
◽
Growth Factor Receptor
◽
Vascular Endothelial
◽
Advanced Solid Tumors
◽
Endothelial Growth Factor
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