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A first-in-human phase I study of BKM120, an oral pan-class I PI3K inhibitor, in patients (pts) with advanced solid tumors.
Journal of Clinical Oncology
◽
10.1200/jco.2010.28.15_suppl.3003
◽
2010
◽
Vol 28
(15_suppl)
◽
pp. 3003-3003
◽
Cited By ~ 17
Author(s):
J. Baselga
◽
M. J. De Jonge
◽
J. Rodon
◽
H. A. Burris
◽
D. C. Birle
◽
...
Keyword(s):
Phase I
◽
Solid Tumors
◽
Phase I Study
◽
Pi3k Inhibitor
◽
Class I
◽
Advanced Solid Tumors
Download Full-text
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First-in-Human Phase I Study of Pictilisib (GDC-0941), a Potent Pan–Class I Phosphatidylinositol-3-Kinase (PI3K) Inhibitor, in Patients with Advanced Solid Tumors
Clinical Cancer Research
◽
10.1158/1078-0432.ccr-14-0947
◽
2014
◽
Vol 21
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◽
pp. 77-86
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Cited By ~ 157
Author(s):
Debashis Sarker
◽
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Phase I
◽
Solid Tumors
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Phase I Study
◽
Pi3k Inhibitor
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Class I
◽
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Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of SAR245408 (XL147), an Oral Pan-Class I PI3K Inhibitor, in Patients with Advanced Solid Tumors
Clinical Cancer Research
◽
10.1158/1078-0432.ccr-13-1777
◽
2013
◽
Vol 20
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◽
pp. 233-245
◽
Cited By ~ 113
Author(s):
Geoffrey I. Shapiro
◽
Jordi Rodon
◽
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◽
Eunice L. Kwak
◽
Jose Baselga
◽
...
Keyword(s):
Phase I
◽
Solid Tumors
◽
Pi3k Inhibitor
◽
Class I
◽
Advanced Solid Tumors
◽
Pharmacodynamic Study
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First-in-human phase I study of the oral PI3K inhibitor BEZ235 in patients (pts) with advanced solid tumors.
Journal of Clinical Oncology
◽
10.1200/jco.2010.28.15_suppl.3005
◽
2010
◽
Vol 28
(15_suppl)
◽
pp. 3005-3005
◽
Cited By ~ 66
Author(s):
H. Burris
◽
J. Rodon
◽
S. Sharma
◽
R. S. Herbst
◽
J. Tabernero
◽
...
Keyword(s):
Phase I
◽
Solid Tumors
◽
Phase I Study
◽
Pi3k Inhibitor
◽
Advanced Solid Tumors
Download Full-text
A first-in-human phase I study of intravenous PI3K inhibitor BAY 80-6946 in patients with advanced solid tumors: Results of dose-escalation phase.
Journal of Clinical Oncology
◽
10.1200/jco.2011.29.15_suppl.3035
◽
2011
◽
Vol 29
(15_suppl)
◽
pp. 3035-3035
◽
Cited By ~ 9
Author(s):
A. Patnaik
◽
L. J. Appleman
◽
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◽
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◽
M. Beeram
◽
...
Keyword(s):
Phase I
◽
Solid Tumors
◽
Dose Escalation
◽
Phase I Study
◽
Pi3k Inhibitor
◽
Advanced Solid Tumors
Download Full-text
A phase I study evaluating GDC-0941, an oral phosphoinositide-3 kinase (PI3K) inhibitor, in patients with advanced solid tumors or multiple myeloma.
Journal of Clinical Oncology
◽
10.1200/jco.2011.29.15_suppl.3021
◽
2011
◽
Vol 29
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◽
pp. 3021-3021
◽
Cited By ~ 18
Author(s):
V. Moreno Garcia
◽
R. D. Baird
◽
K. J. Shah
◽
B. Basu
◽
N. Tunariu
◽
...
Keyword(s):
Multiple Myeloma
◽
Phase I
◽
Solid Tumors
◽
Phase I Study
◽
Pi3k Inhibitor
◽
Advanced Solid Tumors
◽
Phosphoinositide 3 Kinase
Download Full-text
Correction: Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of SAR245408 (XL147), an Oral Pan-Class I PI3K Inhibitor, in Patients with Advanced Solid Tumors
Clinical Cancer Research
◽
10.1158/1078-0432.ccr-15-0185
◽
2015
◽
Vol 21
(9)
◽
pp. 2192-2192
◽
Cited By ~ 1
Keyword(s):
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◽
Solid Tumors
◽
Pi3k Inhibitor
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◽
Advanced Solid Tumors
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◽
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Phase I dose-escalation and -expansion study of buparlisib (BKM120), an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors
Investigational New Drugs
◽
10.1007/s10637-014-0082-9
◽
2014
◽
Vol 32
(4)
◽
pp. 670-681
◽
Cited By ~ 121
Author(s):
Jordi Rodon
◽
Irene Braña
◽
Lillian L Siu
◽
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◽
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◽
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Phase I
◽
Solid Tumors
◽
Dose Escalation
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◽
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Phase I study of alpelisib (BYL719), an α-specific PI3K inhibitor, in Japanese patients with advanced solid tumors
Cancer Science
◽
10.1111/cas.13923
◽
2019
◽
Vol 110
(3)
◽
pp. 1021-1031
◽
Cited By ~ 12
Author(s):
Yuichi Ando
◽
Satoru Iwasa
◽
Shunji Takahashi
◽
Hideo Saka
◽
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Solid Tumors
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Phase I Study
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Phase I Trial of a Tablet Formulation of Pilaralisib, a Pan‐Class I PI3K Inhibitor, in Patients with Advanced Solid Tumors
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◽
10.1634/theoncologist.2017-0691
◽
2018
◽
Vol 23
(4)
◽
pp. 401
◽
Cited By ~ 4
Author(s):
Gerald Edelman
◽
Jordi Rodon
◽
Joanne Lager
◽
Christelle Castell
◽
Jason Jiang
◽
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Keyword(s):
Phase I
◽
Solid Tumors
◽
Phase I Trial
◽
Tablet Formulation
◽
Pi3k Inhibitor
◽
Class I
◽
Advanced Solid Tumors
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Abstract B159: Phase I dose-escalation study of BKM120, an oral pan-class I PI3K inhibitor, in Japanese patients with advanced solid tumors.
10.1158/1535-7163.targ-11-b159
◽
2011
◽
Cited By ~ 1
Author(s):
Toshihiko Doi
◽
Yuichi Ando
◽
Hideaki Bando
◽
Takayuki Yoshino
◽
Megumi Inada
◽
...
Keyword(s):
Phase I
◽
Solid Tumors
◽
Dose Escalation
◽
Japanese Patients
◽
Pi3k Inhibitor
◽
Class I
◽
Advanced Solid Tumors
◽
Dose Escalation Study
Download Full-text
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