scholarly journals First-in-Human Phase I Study of Pictilisib (GDC-0941), a Potent Pan–Class I Phosphatidylinositol-3-Kinase (PI3K) Inhibitor, in Patients with Advanced Solid Tumors

2014 ◽  
Vol 21 (1) ◽  
pp. 77-86 ◽  
Author(s):  
Debashis Sarker ◽  
Joo Ern Ang ◽  
Richard Baird ◽  
Rebecca Kristeleit ◽  
Krunal Shah ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Phase I Study ◽  
Pi3k Inhibitor ◽  
Class I ◽  
Advanced Solid Tumors ◽  
Phosphatidylinositol 3 Kinase ◽  
Phosphatidylinositol 3

A first-in-human phase I study of BKM120, an oral pan-class I PI3K inhibitor, in patients (pts) with advanced solid tumors.

2010 ◽  
Vol 28 (15_suppl) ◽  
pp. 3003-3003 ◽  
Author(s):  
J. Baselga ◽  
M. J. De Jonge ◽  
J. Rodon ◽  
H. A. Burris ◽  
D. C. Birle ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Phase I Study ◽  
Pi3k Inhibitor ◽  
Class I ◽  
Advanced Solid Tumors

scholarly journals Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of SAR245408 (XL147), an Oral Pan-Class I PI3K Inhibitor, in Patients with Advanced Solid Tumors

2013 ◽  
Vol 20 (1) ◽  
pp. 233-245 ◽  
Author(s):  
Geoffrey I. Shapiro ◽  
Jordi Rodon ◽  
Cynthia Bedell ◽  
Eunice L. Kwak ◽  
Jose Baselga ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Pi3k Inhibitor ◽  
Class I ◽  
Advanced Solid Tumors ◽  
Pharmacodynamic Study

First-in-human phase I study of the oral PI3K inhibitor BEZ235 in patients (pts) with advanced solid tumors.

2010 ◽  
Vol 28 (15_suppl) ◽  
pp. 3005-3005 ◽  
Author(s):  
H. Burris ◽  
J. Rodon ◽  
S. Sharma ◽  
R. S. Herbst ◽  
J. Tabernero ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Phase I Study ◽  
Pi3k Inhibitor ◽  
Advanced Solid Tumors

A first-in-human phase I study of intravenous PI3K inhibitor BAY 80-6946 in patients with advanced solid tumors: Results of dose-escalation phase.

2011 ◽  
Vol 29 (15_suppl) ◽  
pp. 3035-3035 ◽  
Author(s):  
A. Patnaik ◽  
L. J. Appleman ◽  
J. M. Mountz ◽  
R. K. Ramanathan ◽  
M. Beeram ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Phase I Study ◽  
Pi3k Inhibitor ◽  
Advanced Solid Tumors
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