Induction chemotherapy (IC) docetaxel (T), cisplatin (P), 5-fluorouracil (F) (TPF), or TP followed by concomitant boost radiotherapy (R) with or without cetuximab (E) for functional organ preservation (FOP) of resectable laryngeal and hypopharyngeal cancer (LHSCC): First results of the phase II randomized DeLOS-II study.

Andreas Dietz; Michael Flentje; Rudolf Hagen; Ulrike Bockmuehl; Oliver Koelbl; Volker Schilling; Georg Maschmeyer; Ursula Schroeder; Christian Sittel; Martin Goerner; Thomas Lenarz; Jens Peter Klussmann; Orlando Guntinas-Lichius; Claudia Rudack; Sabine Reinisch; Thomas Foerg; Martin Westhofen; Hans Juergen Welkoborsky; Dirk Esser; Ulrich Keilholz

doi:10.1200/jco.2014.32.15_suppl.6016

Induction chemotherapy (IC) docetaxel (T), cisplatin (P), 5-fluorouracil (F) (TPF), or TP followed by concomitant boost radiotherapy (R) with or without cetuximab (E) for functional organ preservation (FOP) of resectable laryngeal and hypopharyngeal cancer (LHSCC): First results of the phase II randomized DeLOS-II study.

Journal of Clinical Oncology ◽

10.1200/jco.2014.32.15_suppl.6016 ◽

2014 ◽

Vol 32 (15_suppl) ◽

pp. 6016-6016 ◽

Cited By ~ 5

Author(s):

Andreas Dietz ◽

Michael Flentje ◽

Rudolf Hagen ◽

Ulrike Bockmuehl ◽

Oliver Koelbl ◽

...

Keyword(s):

Induction Chemotherapy ◽

Phase Ii ◽

Organ Preservation ◽

Hypopharyngeal Cancer ◽

Concomitant Boost ◽

First Results ◽

Boost Radiotherapy

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Phase II organ-preservation trial: Concurrent cisplatin and radiotherapy for advanced laryngeal cancer after response to docetaxel, cisplatin, and 5-fluorouracil-based induction chemotherapy

Head & Neck ◽

10.1002/hed.24571 ◽

2016 ◽

Vol 39 (2) ◽

pp. 227-233 ◽

Cited By ~ 8

Author(s):

Aron Popovtzer ◽

Hanna Burnstein ◽

Salomon Stemmer ◽

Dror Limon ◽

Ohad Hili ◽

...

Keyword(s):

Induction Chemotherapy ◽

Phase Ii ◽

Laryngeal Cancer ◽

Organ Preservation

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Induction chemotherapy (IC) followed by radiotherapy (RT) versus cetuximab plus IC and RT in advanced laryngeal/hypopharyngeal cancer resectable only by total laryngectomy—final results of the larynx organ preservation trial DeLOS-II

Annals of Oncology ◽

10.1093/annonc/mdy332 ◽

2018 ◽

Vol 29 (10) ◽

pp. 2105-2114 ◽

Cited By ~ 11

Author(s):

A. Dietz ◽

G. Wichmann ◽

T. Kuhnt ◽

L. Pfreundner ◽

R. Hagen ◽

...

Keyword(s):

Induction Chemotherapy ◽

Total Laryngectomy ◽

Organ Preservation ◽

Hypopharyngeal Cancer

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Docetaxel, cisplatin, and fluorouracil induction chemotherapy followed by accelerated fractionation/concomitant boost radiation and concurrent cisplatin in patients with advanced squamous cell head and neck cancer: A Southwest Oncology Group phase II trial (S0216)

Head & Neck ◽

10.1002/hed.21179 ◽

2009 ◽

pp. NA-NA ◽

Cited By ~ 4

Author(s):

David J. Adelstein ◽

James Moon ◽

Ehab Hanna ◽

P. G. Shankar Giri ◽

Glenn M. Mills ◽

...

Keyword(s):

Head And Neck Cancer ◽

Head And Neck ◽

Induction Chemotherapy ◽

Phase Ii ◽

Phase Ii Trial ◽

Oncology Group ◽

Southwest Oncology Group ◽

Concomitant Boost ◽

Accelerated Fractionation ◽

Boost Radiation

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8533 POSTER First Results of an Uncontrolled, Phase II Trial of Induction Chemotherapy With Cetuximab and Docetaxel-Cisplatin-5FU Followed by Cetuximab+Radiotherapy in the Responders in Locally Advanced Resectable Squamous Cell Cancer of the Head and Neck

European Journal of Cancer ◽

10.1016/s0959-8049(11)72175-x ◽

2011 ◽

Vol 47 ◽

pp. S553 ◽

Cited By ~ 2

Author(s):

E. Remenar ◽

J. Lövey ◽

P. Koltai ◽

K. Horvath ◽

M. Gödeny ◽

...

Keyword(s):

Head And Neck ◽

Induction Chemotherapy ◽

Phase Ii ◽

Squamous Cell ◽

Phase Ii Trial ◽

Squamous Cell Cancer ◽

Cell Cancer ◽

Locally Advanced ◽

First Results

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A randomized phase II trial of cetuximab-based induction chemotherapy followed by concurrent cetuximab, 5-FU, hydroxyurea, and hyperfractionated radiation (CetuxFHX), or cetuximab, cisplatin, and accelerated radiation with concomitant boost (CetuxPX) in patients with locoregionally advanced head and neck cancer (HNC).

Journal of Clinical Oncology ◽

10.1200/jco.2011.29.15_suppl.5519 ◽

2011 ◽

Vol 29 (15_suppl) ◽

pp. 5519-5519 ◽

Cited By ~ 11

Author(s):

T. Y. Seiwert ◽

D. J. Haraf ◽

E. E. Cohen ◽

E. A. Blair ◽

K. Stenson ◽

...

Keyword(s):

Head And Neck Cancer ◽

Head And Neck ◽

Induction Chemotherapy ◽

Phase Ii ◽

Neck Cancer ◽

Phase Ii Trial ◽

Advanced Head ◽

Randomized Phase Ii ◽

Concomitant Boost

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Phase II study of capecitabine (Xeloda®) and concomitant boost radiotherapy in patients with locally advanced rectal cancer

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2006.05.063 ◽

2006 ◽

Vol 66 (3) ◽

pp. 762-771 ◽

Cited By ~ 85

Author(s):

Sunil Krishnan ◽

Nora A. Janjan ◽

John M. Skibber ◽

Miguel A. Rodriguez-Bigas ◽

Robert A. Wolff ◽

...

Keyword(s):

Rectal Cancer ◽

Phase Ii ◽

Phase Ii Study ◽

Locally Advanced ◽

Advanced Rectal Cancer ◽

Locally Advanced Rectal Cancer ◽

Concomitant Boost ◽

Boost Radiotherapy

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Concomitant boost radiotherapy and multidrug chemotherapy in the neoadjuvant treatment of locally advanced rectal cancer: Results of a phase II study

Acta Oncologica ◽

10.3109/0284186x.2011.582880 ◽

2011 ◽

Vol 50 (8) ◽

pp. 1151-1157 ◽

Cited By ~ 16

Author(s):

Luciana Caravatta ◽

Gilbert D. A. Padula ◽

Vincenzo Picardi ◽

Gabriella Macchia ◽

Francesco Deodato ◽

...

Keyword(s):

Rectal Cancer ◽

Phase Ii ◽

Phase Ii Study ◽

Locally Advanced ◽

Neoadjuvant Treatment ◽

Advanced Rectal Cancer ◽

Locally Advanced Rectal Cancer ◽

Concomitant Boost ◽

Multidrug Chemotherapy ◽

Boost Radiotherapy

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Prospective Phase II Trial of Concomitant Boost Radiotherapy for Stage II Nasopharyngeal Carcinoma

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2007.07.1656 ◽

2007 ◽

Vol 69 (3) ◽

pp. S467 ◽

Cited By ~ 1

Author(s):

J.J. Lu

Keyword(s):

Nasopharyngeal Carcinoma ◽

Phase Ii ◽

Phase Ii Trial ◽

Stage Ii ◽

Concomitant Boost ◽

Prospective Phase ◽

Boost Radiotherapy

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A phase II study of capecitabine and concomitant boost radiotherapy (XRT) in patients (pts) with locally advanced rectal cancer (LARC)

Journal of Clinical Oncology ◽

10.1200/jco.2005.23.16_suppl.3593 ◽

2005 ◽

Vol 23 (16_suppl) ◽

pp. 3593-3593 ◽

Cited By ~ 3

Author(s):

E. H. Lin ◽

J. Skibber ◽

M. Delcos ◽

C. Eng ◽

C. Christopher ◽

...

Keyword(s):

Rectal Cancer ◽

Phase Ii ◽

Phase Ii Study ◽

Locally Advanced ◽

Advanced Rectal Cancer ◽

Locally Advanced Rectal Cancer ◽

Concomitant Boost ◽

Boost Radiotherapy

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A phase I/II trial of induction chemotherapy followed by concomitant docetaxel with concomitant boost radiotherapy (CBR) for cancer of the head and neck

Journal of Clinical Oncology ◽

10.1200/jco.2005.23.16_suppl.5593 ◽

2005 ◽

Vol 23 (16_suppl) ◽

pp. 5593-5593

Author(s):

P. Prellop ◽

R. Ove ◽

R. Meredith ◽

J. Bonner ◽

G. Peters ◽

...

Keyword(s):

Phase I ◽

Head And Neck ◽

Induction Chemotherapy ◽

Concomitant Boost ◽

Boost Radiotherapy

Download Full-text