A phase I study of palbociclib (PALBO) plus everolimus (EVE) and exemestane (EXE) in hormone-receptor positive (HR+)/HER2- metastatic breast cancer (MBC) after progression on a CDK4/6 inhibitor (CDK4/6i): safety, tolerability and pharmacokinetic (PK) analysis.

Phase I ◽

Hormone Receptor ◽

Phase I Study ◽

Metastatic Breast ◽

Abstract CT330: Phase I study of PI3Kα inhibitor BYL719 + aromatase inhibitor (AI) in patients (pts) with hormone receptor-positive (HR+) metastatic breast cancer (MBC)

10.1158/1538-7445.am2015-ct330 ◽

2015 ◽

Cited By ~ 3

Author(s):

Payal D. Shah ◽

Mary E. Moynahan ◽

Shanu Modi ◽

Nicola Hamilton ◽

Betty Ann Caravella ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Aromatase Inhibitor ◽

Hormone Receptor ◽

Phase I Study ◽

Metastatic Breast ◽

Phase I study of everolimus, letrozole, and trastuzumab in patients with hormone receptor-positive metastatic breast cancer or other solid tumors

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-20-2878 ◽

2020 ◽

pp. clincanres.2878.2020

Author(s):

Alexej Ballhausen ◽

Jennifer J. Wheler ◽

Daniel D. Karp ◽

Sarina A. Piha-Paul ◽

Siqing Fu ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Solid Tumors ◽

Hormone Receptor ◽

Phase I Study ◽

Metastatic Breast ◽

Phase I/II study of letrozole and sorafenib as first-line therapy of hormone-receptor positive (HR+) metastatic breast cancer (MBC).

Journal of Clinical Oncology ◽

10.1200/jco.2014.32.15_suppl.531 ◽

2014 ◽

Vol 32 (15_suppl) ◽

pp. 531-531

Author(s):

Antoinette R. Tan ◽

Serena Tsan-Lai Wong ◽

Robert D. Warren ◽

Jennifer Eng-Wong ◽

Minetta C. Liu ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Hormone Receptor ◽

Metastatic Breast ◽

First Line ◽

First Line Therapy ◽

Hormone Receptor Positive ◽

Line Therapy

Sacituzumab govitecan in previously treated hormone receptor-positive/HER2-negative metastatic breast cancer: final results from a phase I/II, single-arm, basket trial

Annals of Oncology ◽

10.1016/j.annonc.2020.09.004 ◽

2020 ◽

Vol 31 (12) ◽

pp. 1709-1718 ◽

Cited By ~ 1

Author(s):

K. Kalinsky ◽

J.R. Diamond ◽

L.T. Vahdat ◽

S.M. Tolaney ◽

D. Juric ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Hormone Receptor ◽

Metastatic Breast ◽

Hormone Receptor Positive ◽

Previously Treated ◽

Basket Trial

Phase I trial of exemestane in combination with metformin and rosiglitazone in nondiabetic obese postmenopausal women with hormone receptor–positive metastatic breast cancer

Cancer Chemotherapy and Pharmacology ◽

10.1007/s00280-012-1977-9 ◽

2012 ◽

Vol 71 (1) ◽

pp. 63-72 ◽

Cited By ~ 27

Author(s):

Francisco J. Esteva ◽

Stacy L. Moulder ◽

Ana M. Gonzalez-Angulo ◽

Joe Ensor ◽

James L. Murray ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Postmenopausal Women ◽

Hormone Receptor ◽

Phase I Trial ◽

Metastatic Breast ◽

Phase I/II study of sorafenib with anastrozole in patients with hormone receptor positive aromatase inhibitor resistant metastatic breast cancer

Breast Cancer Research and Treatment ◽

10.1007/s10549-010-1226-z ◽

2010 ◽

Vol 125 (1) ◽

pp. 137-143 ◽

Cited By ~ 24

Author(s):

Claudine Isaacs ◽

Pia Herbolsheimer ◽

Minetta C. Liu ◽

Mary Wilkinson ◽

Yvonne Ottaviano ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Aromatase Inhibitor ◽

Hormone Receptor ◽

Metastatic Breast ◽

Abstract PD5-3: Phase I trial: PI3Kα inhibitor BYL719 plus aromatase inhibitor (AI) for patients with hormone receptor-positive (HR+) metastatic breast cancer (MBC)

10.1158/1538-7445.sabcs14-pd5-3 ◽

2015 ◽

Cited By ~ 1

Author(s):

Payal D Shah ◽

Mary Ellen Moynahan ◽

Shanu Modi ◽

Betty Ann Caravella ◽

Farrah M Datko ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Aromatase Inhibitor ◽

Hormone Receptor ◽

Phase I Trial ◽

Metastatic Breast ◽

Phase I Study and Pilot Efficacy Analysis of Entinostat, a Novel Histone Deacetylase Inhibitor, in Chinese Postmenopausal Women with Hormone Receptor-Positive Metastatic Breast Cancer

Targeted Oncology ◽

10.1007/s11523-021-00823-4 ◽

2021 ◽

Author(s):

Jiani Wang ◽

Qingyuan Zhang ◽

Qiao Li ◽

Yuxin Mu ◽

Jing Jing ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Histone Deacetylase Inhibitor ◽

Phase I Study ◽

Metastatic Breast ◽

Efficacy Analysis ◽

Hormone Receptor Positive ◽

Deacetylase Inhibitor ◽

Chinese Postmenopausal Women

Phase I/II trial of palbociclib, pembrolizumab and letrozole in patients with hormone receptor-positive metastatic breast cancer

European Journal of Cancer ◽

10.1016/j.ejca.2021.05.035 ◽

2021 ◽

Vol 154 ◽

pp. 11-20

Author(s):

Yuan Yuan ◽

Jin Sun Lee ◽

Susan E. Yost ◽

Paul H. Frankel ◽

Christopher Ruel ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Hormone Receptor ◽

Metastatic Breast ◽

Abstract P5-11-04: A phase I/IIb study of palbociclib (PALBO) plus everolimus (EVE) and exemestane (EXE) in hormone-receptor positive (HR+)/HER2- metastatic breast cancer (MBC) after progression on a CDK4/6 inhibitor (CDK4/6i): Results of the phase II study

10.1158/1538-7445.sabcs19-p5-11-04 ◽

2020 ◽

Cited By ~ 1

Author(s):

Romualdo Barroso-Sousa ◽

Tianyu Li ◽

Lorenzo Trippa ◽

Rebecca Rees ◽

Chelsea Andrews ◽

...

Keyword(s):

Breast Cancer ◽

Phase I ◽

Phase Ii ◽

Hormone Receptor ◽

Phase Ii Study ◽

Metastatic Breast ◽