Clinical Trial Simulation (CTS): A Regulatory Clinical Pharmacology Perspective

Simulation for Designing Clinical Trials ◽

10.1201/9780203910276-14 ◽

2002 ◽

pp. 219-228

Keyword(s):

Clinical Trial ◽

Clinical Pharmacology ◽

Clinical Trial Simulation ◽

Trial Simulation

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Clinical Trial Simulation—A Case Study Incorporating Efficacy and Tolerability Dose Response

Statistics for Biology and Health - Dose Finding in Drug Development ◽

10.1007/0-387-33706-7_8 ◽

2006 ◽

pp. 106-126

Author(s):

Wayne Ewy ◽

Peter Lockwood ◽

Candace Bramson

Keyword(s):

Clinical Trial ◽

Dose Response ◽

Clinical Trial Simulation ◽

Trial Simulation

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Clinical Trial Simulation to Inform Phase 2: Comparison of Concentrated vs. Distributed First-in-Patient Study Designs in Psoriasis

CPT Pharmacometrics & Systems Pharmacology ◽

10.1038/psp.2013.32 ◽

2013 ◽

Vol 2 (7) ◽

pp. 58 ◽

Author(s):

MG Dodds ◽

DH Salinger ◽

J Mandema ◽

JP Gibbs ◽

MA Gibbs

Keyword(s):

Clinical Trial ◽

Clinical Trial Simulation ◽

Phase 2 ◽

Patient Study ◽

Trial Simulation ◽

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Sensitivity Analysis of Pharmacokinetic and Pharmacodynamic Models in Clinical Trial Simulation and Design

Drugs and the Pharmaceutical Sciences - Simulation for Designing Clinical Trials ◽

10.1201/9780203910276.ch8 ◽

2002 ◽

Author(s):

Ivan Nestorov

Keyword(s):

Clinical Trial ◽

Sensitivity Analysis ◽

Clinical Trial Simulation ◽

Trial Simulation

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Clinical Trial Simulation (CTS)

Drugs and the Pharmaceutical Sciences - Simulation for Designing Clinical Trials ◽

10.1201/9780203910276.ch10 ◽

2002 ◽

Author(s):

Lawrence Lesko ◽

Peter Lee

Keyword(s):

Clinical Trial ◽

Clinical Trial Simulation ◽

Trial Simulation

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Deﬁning Covariate Distribution Models for Clinical Trial Simulation

Simulation for Designing Clinical Trials ◽

10.1201/9780203910276-7 ◽

2002 ◽

pp. 49-72

Keyword(s):

Clinical Trial ◽

Clinical Trial Simulation ◽

Distribution Models ◽

Trial Simulation

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Clinical Trial Simulation

Chapman & Hall/CRC Biostatistics Series - Adaptive Design Methods in Clinical Trials ◽

10.1201/9781584887775.ch11 ◽

2006 ◽

pp. 211-237

Keyword(s):

Clinical Trial ◽

Clinical Trial Simulation ◽

Trial Simulation

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Combining Model‐Based Clinical Trial Simulation, Pharmacoeconomics, and Value of Information to Optimize Trial Design

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12579 ◽

2020 ◽

Author(s):

Daniel Hill‐McManus ◽

Dyfrig A. Hughes

Keyword(s):

Clinical Trial ◽

Value Of Information ◽

Trial Design ◽

Clinical Trial Simulation ◽

Model Based ◽

Trial Simulation

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A kinetic-pharmacodynamic model for clinical trial simulation of antidepressant action: Application to clomipramine–lithium interaction

Contemporary Clinical Trials ◽

10.1016/j.cct.2006.09.001 ◽

2007 ◽

Vol 28 (3) ◽

pp. 276-287 ◽

Author(s):

Bérangère Gruwez ◽

Marie-France Poirier ◽

Alain Dauphin ◽

Jean-Pierre Olié ◽

Michel Tod

Keyword(s):

Clinical Trial ◽

Pharmacodynamic Model ◽

Clinical Trial Simulation ◽

Lithium Interaction ◽

Trial Simulation ◽

Antidepressant Action

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Clinical Trial Simulation in Alzheimer’s Disease

Applied Pharmacometrics - AAPS Advances in the Pharmaceutical Sciences Series ◽

10.1007/978-1-4939-1304-6_15 ◽

2014 ◽

pp. 451-476 ◽

Author(s):

Brian Corrigan ◽

Kaori Ito ◽

James Rogers ◽

Daniel Polhamus ◽

Diane Stephenson ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Clinical Trial ◽

Clinical Trial Simulation ◽

Trial Simulation

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Abstract 3373: Clinical trial simulation for the individualization of docetaxel dosing.

10.1158/1538-7445.am2013-3373 ◽

2013 ◽

Author(s):

Carlos Perez-Ruixo ◽

Belen Valenzuela ◽

Mario González-Sales ◽

Emiliano Calvo

Keyword(s):

Clinical Trial ◽

Clinical Trial Simulation ◽

Trial Simulation

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