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Clinical Trial Simulation in Alzheimer’s Disease
Applied Pharmacometrics - AAPS Advances in the Pharmaceutical Sciences Series
◽
10.1007/978-1-4939-1304-6_15
◽
2014
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pp. 451-476
◽
Cited By ~ 1
Author(s):
Brian Corrigan
◽
Kaori Ito
◽
James Rogers
◽
Daniel Polhamus
◽
Diane Stephenson
◽
...
Keyword(s):
Alzheimer’S Disease
◽
Alzheimer's Disease
◽
Clinical Trial
◽
Clinical Trial Simulation
◽
Trial Simulation
Download Full-text
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Cited By
References
Application of Clinical Trial Simulation to Compare Proof-of-Concept Study Designs for Drugs with a Slow Onset of Effect; An Example in Alzheimer's Disease
Pharmaceutical Research
◽
10.1007/s11095-006-9048-8
◽
2006
◽
Vol 23
(9)
◽
pp. 2050-2059
◽
Cited By ~ 38
Author(s):
Peter Lockwood
◽
Wayne Ewy
◽
David Hermann
◽
Nick Holford
Keyword(s):
Alzheimer’S Disease
◽
Alzheimer's Disease
◽
Clinical Trial
◽
Clinical Trial Simulation
◽
Proof Of Concept
◽
Concept Study
◽
Trial Simulation
◽
Study Designs
◽
Slow Onset
Download Full-text
P4-248: Clinical trial simulation to assess the probabilities of technical success for drugs in Alzheimer's disease proof-of-concept studies
Alzheimer s & Dementia
◽
10.1016/j.jalz.2011.05.2273
◽
2011
◽
Vol 7
◽
pp. S793-S793
Author(s):
James Rogers
◽
Brian Corrigan
◽
Terence Fullerton
Keyword(s):
Alzheimer’S Disease
◽
Alzheimer's Disease
◽
Clinical Trial
◽
Clinical Trial Simulation
◽
Proof Of Concept
◽
Technical Success
◽
Trial Simulation
Download Full-text
A Randomized, Double-Blind Phase 2b Proof of Concept Clinical Trial in Early Alzheimer's Disease with BAN2401, an Anti-Aβ Protofibril Antibody
SSRN Electronic Journal
◽
10.2139/ssrn.3672342
◽
2020
◽
Author(s):
Chad Swanson
◽
Yong Zhang
◽
Shobha Dhadda
◽
Jinping Wang
◽
June Kaplow
◽
...
Keyword(s):
Alzheimer’S Disease
◽
Alzheimer's Disease
◽
Clinical Trial
◽
Proof Of Concept
◽
Double Blind
◽
Early Alzheimer’S Disease
Download Full-text
P2-027: TARGET ENGAGEMENT IN A PHASE II CLINICAL TRIAL OF AAV2-NGF GENE THERAPY FOR ALZHEIMER'S DISEASE
Alzheimer s & Dementia
◽
10.1016/j.jalz.2018.06.711
◽
2006
◽
Vol 14
(7S_Part_12)
◽
pp. P677-P677
Author(s):
Michael J. Castle
◽
Fernando Calvo Baltanas
◽
Imre Kovacs
◽
Alan H. Nagahara
◽
Krystof S. Bankiewicz
◽
...
Keyword(s):
Alzheimer’S Disease
◽
Alzheimer's Disease
◽
Clinical Trial
◽
Gene Therapy
◽
Phase Ii
◽
Phase Ii Clinical Trial
◽
Target Engagement
◽
Ngf Gene
Download Full-text
Medical nutrition in Alzheimer's disease: First results and clinical trial
European Journal of Pharmacology
◽
10.1016/j.ejphar.2011.09.213
◽
2011
◽
Vol 668
◽
pp. e8-e9
◽
Cited By ~ 1
Author(s):
P. Scheltens
Keyword(s):
Alzheimer’S Disease
◽
Alzheimer's Disease
◽
Clinical Trial
◽
First Results
◽
Medical Nutrition
Download Full-text
Clinical Trial Simulation—A Case Study Incorporating Efficacy and Tolerability Dose Response
Statistics for Biology and Health - Dose Finding in Drug Development
◽
10.1007/0-387-33706-7_8
◽
2006
◽
pp. 106-126
Author(s):
Wayne Ewy
◽
Peter Lockwood
◽
Candace Bramson
Keyword(s):
Clinical Trial
◽
Dose Response
◽
Clinical Trial Simulation
◽
Trial Simulation
Download Full-text
P4-045: Longitudinal ADC changes in Alzheimer's disease in a multi-center clinical trial setting
Alzheimer s & Dementia
◽
10.1016/j.jalz.2011.05.2065
◽
2011
◽
Vol 7
◽
pp. S713-S713
Author(s):
Luc Bracoud
◽
Angelika Caputo
◽
Chahin Pachai
◽
Boubakeur Belaroussi
◽
Ana Graf
◽
...
Keyword(s):
Alzheimer’S Disease
◽
Alzheimer's Disease
◽
Clinical Trial
◽
Clinical Trial Setting
◽
Trial Setting
Download Full-text
A clinical trial to validate event‐related potential markers of Alzheimer's disease in outpatient settings
Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
◽
10.1016/j.dadm.2015.08.004
◽
2015
◽
Vol 1
(4)
◽
pp. 387-394
◽
Cited By ~ 7
Author(s):
Marco Cecchi
◽
Dennis K. Moore
◽
Carl H. Sadowsky
◽
Paul R. Solomon
◽
P. Murali Doraiswamy
◽
...
Keyword(s):
Alzheimer’S Disease
◽
Alzheimer's Disease
◽
Clinical Trial
◽
Event Related Potential
◽
Outpatient Settings
Download Full-text
L-acetylcarnitine and Alzheimer's disease: Results of a controlled clinical trial
Neurobiology of Aging
◽
10.1016/0197-4580(90)90923-n
◽
1990
◽
Vol 11
(3)
◽
pp. 342-343
◽
Cited By ~ 1
Keyword(s):
Alzheimer’S Disease
◽
Alzheimer's Disease
◽
Clinical Trial
◽
Controlled Clinical Trial
Download Full-text
Potential of Low Dose Leuco-Methylthioninium Bis(Hydromethanesulphonate) (LMTM) Monotherapy for Treatment of Mild Alzheimer’s Disease: Cohort Analysis as Modified Primary Outcome in a Phase III Clinical Trial
Journal of Alzheimer s Disease
◽
10.3233/jad-170560
◽
2017
◽
Vol 61
(1)
◽
pp. 435-457
◽
Cited By ~ 52
Author(s):
Gordon K. Wilcock
◽
Serge Gauthier
◽
Giovanni B. Frisoni
◽
Jianping Jia
◽
Jiri H. Hardlund
◽
...
Keyword(s):
Alzheimer’S Disease
◽
Alzheimer's Disease
◽
Clinical Trial
◽
Primary Outcome
◽
Low Dose
◽
Cohort Analysis
◽
Phase Iii
◽
Phase Iii Clinical Trial
Download Full-text
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