Clinical Trial Simulation—A Case Study Incorporating Efficacy and Tolerability Dose Response

Statistics for Biology and Health - Dose Finding in Drug Development ◽

10.1007/0-387-33706-7_8 ◽

2006 ◽

pp. 106-126

Author(s):

Wayne Ewy ◽

Peter Lockwood ◽

Candace Bramson

Keyword(s):

Clinical Trial ◽

Dose Response ◽

Clinical Trial Simulation ◽

Trial Simulation

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The Rheumatoid Arthritis Drug Development Model: a case study in Bayesian clinical trial simulation

Pharmaceutical Statistics ◽

10.1002/pst.368 ◽

2009 ◽

pp. n/a-n/a ◽

Cited By ~ 2

Author(s):

Richard M. Nixon ◽

Anthony O'Hagan ◽

Jeremy Oakley ◽

Jason Madan ◽

John W. Stevens ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Clinical Trial ◽

Drug Development ◽

Development Model ◽

Clinical Trial Simulation ◽

Trial Simulation

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Misclassification and discordance of measured blood pressure from patient’s true blood pressure in current clinical practice: a clinical trial simulation case study

Journal of Pharmacokinetics and Pharmacodynamics ◽

10.1007/s10928-012-9250-8 ◽

2012 ◽

Vol 39 (3) ◽

pp. 283-294 ◽

Cited By ~ 11

Author(s):

Yuyan Jin ◽

Robert Bies ◽

Marc R. Gastonguay ◽

Norman Stockbridge ◽

Jogarao Gobburu ◽

...

Keyword(s):

Blood Pressure ◽

Clinical Trial ◽

Clinical Practice ◽

Clinical Trial Simulation ◽

Current Clinical Practice ◽

Trial Simulation ◽

True Blood

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Model-Based Integration for Clinical Trial Simulation and Design: A Phase II Case Study for Naratriptan

Simulation for Designing Clinical Trials ◽

10.1201/9780203910276-20 ◽

2002 ◽

pp. 331-344

Keyword(s):

Clinical Trial ◽

Phase Ii ◽

Clinical Trial Simulation ◽

Model Based ◽

Trial Simulation

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Predicting the Outcome of Phase III Trials using Phase II Data: A Case Study of Clinical Trial Simulation in Late Stage Drug Development

Basic & Clinical Pharmacology & Toxicology ◽

10.1111/j.1742-7843.2005.pto960314.x ◽

2005 ◽

Vol 96 (3) ◽

pp. 235-241 ◽

Cited By ~ 20

Author(s):

Filip De Ridder

Keyword(s):

Clinical Trial ◽

Drug Development ◽

Phase Ii ◽

Late Stage ◽

Phase Iii ◽

Clinical Trial Simulation ◽

Trial Simulation ◽

Phase Iii Trials

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Clinical Trial Simulation to Inform Phase 2: Comparison of Concentrated vs. Distributed First-in-Patient Study Designs in Psoriasis

CPT Pharmacometrics & Systems Pharmacology ◽

10.1038/psp.2013.32 ◽

2013 ◽

Vol 2 (7) ◽

pp. 58 ◽

Cited By ~ 8

Author(s):

MG Dodds ◽

DH Salinger ◽

J Mandema ◽

JP Gibbs ◽

MA Gibbs

Keyword(s):

Clinical Trial ◽

Clinical Trial Simulation ◽

Phase 2 ◽

Patient Study ◽

Trial Simulation ◽

Study Designs

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Sensitivity Analysis of Pharmacokinetic and Pharmacodynamic Models in Clinical Trial Simulation and Design

Drugs and the Pharmaceutical Sciences - Simulation for Designing Clinical Trials ◽

10.1201/9780203910276.ch8 ◽

2002 ◽

Author(s):

Ivan Nestorov

Keyword(s):

Clinical Trial ◽

Sensitivity Analysis ◽

Clinical Trial Simulation ◽

Trial Simulation

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Clinical Trial Simulation (CTS)

Drugs and the Pharmaceutical Sciences - Simulation for Designing Clinical Trials ◽

10.1201/9780203910276.ch10 ◽

2002 ◽

Author(s):

Lawrence Lesko ◽

Peter Lee

Keyword(s):

Clinical Trial ◽

Clinical Trial Simulation ◽

Trial Simulation

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Deﬁning Covariate Distribution Models for Clinical Trial Simulation

Simulation for Designing Clinical Trials ◽

10.1201/9780203910276-7 ◽

2002 ◽

pp. 49-72

Keyword(s):

Clinical Trial ◽

Clinical Trial Simulation ◽

Distribution Models ◽

Trial Simulation

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Clinical Trial Simulation (CTS): A Regulatory Clinical Pharmacology Perspective

Simulation for Designing Clinical Trials ◽

10.1201/9780203910276-14 ◽

2002 ◽

pp. 219-228

Keyword(s):

Clinical Trial ◽

Clinical Pharmacology ◽

Clinical Trial Simulation ◽

Trial Simulation

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