Subthalamic nucleus and substantia nigra pars reticulata stimulation: the Grenoble experience

2020 ◽  
pp. 335-348
Author(s):  
Alim-Louis Benabid ◽  
Adnan Koudsie ◽  
Stephan Chabardes ◽  
Laurent Vercueil ◽  
Abdelhamid Benazzouz ◽  
...  
Author(s):  
Charles J. Wilson

The subthalamo-pallidal system constitutes the second layer of circuitry in the basal ganglia, downstream of the striatum. It consists of four nuclei. Two of them, the external segment of the globus pallidus (GPe) and subthalamic nucleus (STN), make their connections primarily within the basal ganglia. The others, the internal segment of the globus pallidus (GPi) and the substantia nigra pars reticulata (SNr), are the output nuclei of the basal ganglia. Collectively, their axons distribute collaterals to all the targets of the basal ganglia. Rare interneurons have been reported in each of them from studies of Golgi-stained preparations, but they have not so far been confirmed using more modern methods. The circuit as described here is based primarily on studies of the axonal arborizations of neurons stained individually by intracellular or juxtacellular labeling.


Brain ◽  
2011 ◽  
Vol 134 (11) ◽  
pp. 3276-3289 ◽  
Author(s):  
Timothy P. Gilmour ◽  
Brigitte Piallat ◽  
Christopher A. Lieu ◽  
Kala Venkiteswaran ◽  
Renuka Ramachandra ◽  
...  

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