Applications of Metabolomics to Microbial “Cell Factories” for Biomanufacturing

2011 ◽  
pp. 137-163
Author(s):  
David Mousdale ◽  
Brian McNeil
Keyword(s):  
Microbial Cell ◽  
Microbial Cell Factories ◽  
Cell Factories

Developing fourth-generation biofuels secreting microbial cell factories for enhanced productivity and efficient product recovery; a review

Fuel ◽  
2021 ◽  
Vol 298 ◽  
pp. 120858
Author(s):  
Sana Malik ◽  
Ayesha Shahid ◽  
Chen-Guang Liu ◽  
Aqib Zafar Khan ◽  
Muhammad Zohaib Nawaz ◽  
...  
Keyword(s):  
Product Recovery ◽  
Microbial Cell ◽  
Fourth Generation ◽  
Microbial Cell Factories ◽  
Cell Factories

Recent advances in engineering of microbial cell factories for intelligent pH regulation and tolerance

2021 ◽  
pp. 2100151
Author(s):  
Xiaopeng Gao ◽  
Ke Xu ◽  
Nadeem Ahmad ◽  
Lei Qin ◽  
Chun Li
Keyword(s):  
Ph Regulation ◽  
Microbial Cell ◽  
Microbial Cell Factories ◽  
Cell Factories ◽  
Recent Advances

Ramanome technology platform for label-free screening and sorting of microbial cell factories at single-cell resolution

2019 ◽  
Vol 37 (6) ◽  
pp. 107388 ◽  
Author(s):  
Yuehui He ◽  
Xixian Wang ◽  
Bo Ma ◽  
Jian Xu
Keyword(s):  
Single Cell ◽  
Microbial Cell ◽  
Label Free ◽  
Technology Platform ◽  
Microbial Cell Factories ◽  
Cell Factories

Microbial cell factories a new dimension in bio-nanotechnology: exploring the robustness of nature

2021 ◽  
pp. 1-31
Author(s):  
Komal Agrawal ◽  
Vijai Kumar Gupta ◽  
Pradeep Verma
Keyword(s):  
Microbial Cell ◽  
Microbial Cell Factories ◽  
Cell Factories

scholarly journals Flux balance analysis indicates that methane is the lowest cost feedstock for microbial cell factories

2017 ◽  
Vol 5 ◽  
pp. 26-33 ◽  
Author(s):  
Austin D. Comer ◽  
Matthew R. Long ◽  
Jennifer L. Reed ◽  
Brian F. Pfleger
Keyword(s):  
Flux Balance Analysis ◽  
Microbial Cell ◽  
Flux Balance ◽  
Microbial Cell Factories ◽  
Cell Factories ◽  
Balance Analysis

scholarly journals Establishing new microbial cell factories for sustainable bioprocesses

2012 ◽  
Vol 29 ◽  
pp. S75-S76
Author(s):  
Mhairi Workman ◽  
Philippe Holt ◽  
Xiaoying Liu
Keyword(s):  
Microbial Cell ◽  
Microbial Cell Factories ◽  
Cell Factories

scholarly journals Recombinant production of eukaryotic cytochrome P450s in microbial cell factories

2018 ◽  
Vol 38 (2) ◽  
Author(s):  
Johanna Hausjell ◽  
Heidi Halbwirth ◽  
Oliver Spadiut
Keyword(s):  
Cytochrome P450s ◽  
Microbial Cell ◽  
Cytochrome P450 Reductase ◽  
Redox Partner ◽  
Microbial Cell Factories ◽  
Cell Factories ◽  
Recombinant Production ◽  
Membrane Bound ◽  
Essential Reactions ◽  
Synthesis Of Hormones

Cytochrome P450s (P450s) comprise one of the largest known protein families. They occur in every kingdom of life and catalyze essential reactions, such as carbon source assimilation, synthesis of hormones and secondary metabolites, or degradation of xenobiotics. Due to their outstanding ability of specifically hydroxylating complex hydrocarbons, there is a great demand to use these enzymes for biocatalysis, including applications at an industrial scale. Thus, the recombinant production of these enzymes is intensively investigated. However, especially eukaryotic P450s are difficult to produce. Challenges are faced due to complex cofactor requirements and the availability of a redox-partner (cytochrome P450 reductase, CPR) can be a key element to get active P450s. Additionally, most eukaryotic P450s are membrane bound which complicates the recombinant production. This review describes current strategies for expression of P450s in the microbial cell factories Escherichia coli, Saccharomyces cerevisiae, and Pichia pastoris.

Engineering of microbial cell factories for production of plant-based natural products

2021 ◽  
pp. 381-392
Author(s):  
Julia Gallego-Jara ◽  
Gema Lozano Terol ◽  
Rosa Alba Sola Martínez ◽  
Manuel Cánovas Díaz ◽  
Teresa de Diego Puente
Keyword(s):  
Natural Products ◽  
Microbial Cell ◽  
Microbial Cell Factories ◽  
Cell Factories

An introduction to microbial cell factories for production of biomolecules

2021 ◽  
pp. 1-19
Author(s):  
Nisarg Gohil ◽  
Gargi Bhattacharjee ◽  
Vijai Singh
Keyword(s):  
Microbial Cell ◽  
Microbial Cell Factories ◽  
Cell Factories
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