Substance Abuse in Schizophrenia: Biological Factors Mediating Comorbidity and the Potential Role of Atypical Antipsychotic Drugs

2004 ◽  
Vol 27 (6) ◽  
pp. 795-796
Author(s):  
Andrew James Goudie ◽  
Jonathan Charles Cole

Behrendt & Young's (B&Y's) novel “unifying model” of hallucinations, although comprehensive, fails to incorporate research into the possible role of 5-HT2A receptors in the mode of action of novel “atypical” antipsychotic drugs (which treat hallucinations effectively), and into the role of such receptors, which are located in thalamocortical circuits, in mediating drug-induced hallucinations.


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