Predicting the Drug–Drug Interaction Mediated by CYP3A4 Inhibition: Method Development and Performance Evaluation

2021 ◽  
Vol 24 (1) ◽  
Author(s):  
Hong-can Ren ◽  
Yang Sai ◽  
Tao Chen ◽  
Chun Zhang ◽  
Lily Tang ◽  
...  
Keyword(s):  
Performance Evaluation ◽  
Drug Interaction ◽  
Method Development ◽  
Cyp3a4 Inhibition ◽  
Drug Drug Interaction ◽  
And Performance

A Combined Model for Predicting CYP3A4 Clinical Net Drug-Drug Interaction Based on CYP3A4 Inhibition, Inactivation, and Induction Determined in Vitro

2008 ◽  
Vol 36 (8) ◽  
pp. 1698-1708 ◽  
Author(s):  
Odette A. Fahmi ◽  
Tristan S. Maurer ◽  
Mary Kish ◽  
Edwin Cardenas ◽  
Sherri Boldt ◽  
...  
Keyword(s):  
Drug Interaction ◽  
Combined Model ◽  
Cyp3a4 Inhibition ◽  
Drug Drug Interaction

QSAR Modelling of CYP3A4 Inhibition as a Screening Tool in the Context of DrugDrug Interaction Studies

2012 ◽  
Vol 31 (9) ◽  
pp. 669-677 ◽  
Author(s):  
Véronique Hamon ◽  
Dragos Horvath ◽  
Cédric Gaudin ◽  
Julie Desrivot ◽  
Céline Junges ◽  
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Keyword(s):  
Drug Interaction ◽  
Screening Tool ◽  
Cyp3a4 Inhibition ◽  
Interaction Studies ◽  
Qsar Modelling ◽  
Drug Drug Interaction
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