scholarly journals Studies on Formulation Development of Mucoadhesive Sustained Release Itraconazole Tablet Using Response Surface Methodology

2008 ◽  
Vol 9 (3) ◽  
Author(s):  
Ashwini Madgulkar ◽  
Shivajirao Kadam ◽  
Varsha Pokharkar
Keyword(s):  
Response Surface Methodology ◽  
Sustained Release ◽  
Response Surface ◽  
Formulation Development

scholarly journals Optimization of Sustained-Release Propranolol Dosage form Using Factorial Design and Response Surface Methodology

2004 ◽  
Vol 27 (10) ◽  
pp. 1626-1629 ◽  
Author(s):  
Yaw-Bin Huang ◽  
Yi-Hung Tsai ◽  
Wan-Chiech Yang ◽  
Jui-Sheng Chang ◽  
Pao-Chu Wu
Keyword(s):  
Response Surface Methodology ◽  
Sustained Release ◽  
Factorial Design ◽  
Response Surface ◽  
Dosage Form

scholarly journals Use of Response Surface Methodology in the Formulation and Optimization of Bisoprolol Fumarate Matrix Tablets for Sustained Drug Release

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Jadupati Malakar ◽  
Amit Kumar Nayak ◽  
Soumita Goswami
Keyword(s):  
Response Surface Methodology ◽  
Drug Release ◽  
Sustained Release ◽  
Response Surface ◽  
Diffusion Mechanism ◽  
Matrix Tablets ◽  
Fickian Diffusion ◽  
Order Model ◽  
Sustained Drug Release ◽  
Predicted Values

The aim of this investigation was to develop and optimize bisoprolol fumarate matrix tablets for sustained release application by response surface methodology based on 23 factorial design. The effects of the amounts of calcium alginate, HPMC K4M, and Carbopol 943 in bisoprolol fumarate matrix tablets on the properties of bisoprolol fumarate sustained release matrix tablets like drug release and hardness were analyzed and optimized. The observed responses were coincided well with the predicted values by the experimental design. The optimized bisoprolol fumarate matrix tablets showed prolonged sustained release of bisoprolol fumarate over 6 hours. These matrix tablets followed the first-order model with anomalous (non-Fickian) diffusion mechanism.

scholarly journals Formulation and Optimization of Sustained Release Matrix Tablet of Metformin HCl 500 mg Using Response Surface Methodology

2007 ◽  
Vol 127 (8) ◽  
pp. 1281-1290 ◽  
Author(s):  
Uttam MANDAL ◽  
Veeran GOWDA ◽  
Animesh GHOSH ◽  
Senthamil SELVAN ◽  
Sam SOLOMON ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Sustained Release ◽  
Response Surface ◽  
Matrix Tablet ◽  
Metformin Hcl

Formulation and evaluation of natural gum-based sustained release matrix tablets of flurbiprofen using response surface methodology

2009 ◽  
Vol 35 (12) ◽  
pp. 1470-1478 ◽  
Author(s):  
Syed Nisar Hussain Shah ◽  
Sajid Asghar ◽  
Muhammad Akram Choudhry ◽  
Muhammad Sajid Hamid Akash ◽  
Nisar ur Rehman ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Sustained Release ◽  
Response Surface ◽  
Matrix Tablets ◽  
Natural Gum

Formulation and evaluation of natural gum-based sustained release matrix tablets of flurbiprofen using response surface methodology

2009 ◽  
Vol 00 (00) ◽  
pp. 090730035508060-9
Author(s):  
Syed Nisar Hussain Shah ◽  
Sajid Asghar ◽  
Muhammad Akram Choudhry ◽  
Muhammad Sajid Hamid Akash ◽  
Nisar ur Rehman ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Sustained Release ◽  
Response Surface ◽  
Matrix Tablets ◽  
Natural Gum
Sign in / Sign up

Export Citation Format

Share Document