Assessment of Small Intestinal Transit Times in Ulcerative Colitis and Crohn’s Disease Patients with Different Disease Activity Using Video Capsule Endoscopy

2016 ◽  
Vol 18 (2) ◽  
pp. 404-409 ◽  
Author(s):  
Monika Fischer ◽  
Shivi Siva ◽  
John M. Wo ◽  
Hala M. Fadda
Keyword(s):  
Ulcerative Colitis ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Disease Activity ◽  
Capsule Endoscopy ◽  
Intestinal Transit ◽  
Video Capsule Endoscopy ◽  
Small Intestinal Transit ◽  
Transit Times ◽  
Small Intestinal

scholarly journals Capsule Endoscopy for Crohn’s Disease: Current Status of Diagnosis and Management

2016 ◽  
Vol 2016 ◽  
pp. 1-12 ◽  
Author(s):  
Dong-Hoon Yang ◽  
Bora Keum ◽  
Yoon Tae Jeen
Keyword(s):  
Crohn’S Disease ◽  
Small Bowel ◽  
Crohn's Disease ◽  
Disease Activity ◽  
Capsule Endoscopy ◽  
Retention Rate ◽  
Current Status ◽  
Complete Surgical Excision ◽  
Intestinal Involvement ◽  
Small Intestinal

Crohn’s disease (CD) is an idiopathic inflammatory bowel disease involving the small and/or large intestine. More than 50% of Western CD patients and up to 88% of Asian CD patients may have small intestinal involvement. Video capsule endoscopy (VCE) has a higher diagnostic yield than small bowel barium radiography and computed tomography enterography for the detection of small intestinal involvement of CD. VCE also provides diagnostic yields comparable to magnetic resonance- (MR-) based enterography or enteroclysis and may have several advantages over MR-based tests for the detection of early small intestinal lesions. Several studies have suggested the use of VCE-based disease activity scoring systems to evaluate small intestinal mucosal disease activity, although their clinical relevance needs to be further studied. A possible indication for VCE is recurrence monitoring after complete surgical excision of CD-involved segments but its usefulness and efficacy compared with conventional endoscopy should be evaluated. The capsule retention rate ranges from 0 to 5.4% in suspected CD patients and from 0 to 13.2% in established CD patients. If VCE is necessary, significant small bowel stricture should be ruled out before VCE by performing a patency capsule study and/or small bowel radiological study in suspected or established CD patients.

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