An Unusual Case of Cushing's Syndrome Caused by Ectopic Adrenocortical Carcinoma.

2010 ◽  
pp. P2-701-P2-701
Author(s):  
A Yoshihara ◽  
N Watanabe ◽  
N Hiroi ◽  
H Ueshiba ◽  
N Shiraga ◽  
...  
Keyword(s):  
Cushing’S Syndrome ◽  
Adrenocortical Carcinoma ◽  
Unusual Case ◽  
Cushing's Syndrome

QUANTITATIVE ESTIMATION OF URINARY PREGNANETRIOL, PREGNANETRIOLONE, TETRAHYDRO S AND Δ5-PREGNENETRIOL IN THE INVESTIGATION OF ADRENOCORTICAL FUNCTION

1969 ◽  
Vol 60 (4) ◽  
pp. 657-668 ◽  
Author(s):  
Frances J. Thomas ◽  
A. W. Steinbeck
Keyword(s):  
Congenital Adrenal Hyperplasia ◽  
Cushing’S Syndrome ◽  
Adrenocortical Carcinoma ◽  
Quantitative Estimation ◽  
Cushing's Syndrome ◽  
Adrenocortical Function ◽  
Adrenal Hyperplasia ◽  
Ectopic Acth ◽  
Modified Method ◽  
Idiopathic Hirsutism

ABSTRACT A modified method for the estimation of urinary pregnanetriol, pregnanetriol, pregnanetriolone, Δ5-pregnenetriol and tetrahydro S was investigated. The steroids, separated by chromatography, were measured quantitatively, tetrahydro S by reaction with blue tetrazolium and the other three as acetaldehydogenic substances. The excretion of these steroids was studied in suspected instances of adrenal and/or ovarian disease. Urinary pregnanetriol and tetrahydro S levels were normal in Cushing's syndrome, secondary adrenocortical carcinoma, the Stein-Leventhal syndrome, idiopathic hirsutism and hypertension. Tetrahydro S was doubtfully elevated in an instance of ectopic ACTH Cushing's syndrome. Pregnanetriol excretion was elevated in untreated cases of congenital adrenal hyperplasia and after treatment in some. Pregnanetriolone was found in all patients with congenital adrenal hyperplasia, including those receiving cortisone. Pregnanetriolone was also detected in Cushing's syndrome, secondary adrenocortical carcinoma, the Stein-Leventhal syndrome, ectopic ACTH Cushing's syndrome and suspected congenital adrenal hyperplasia. Δ5-pregnenetriol was present as a glucuronide in the Stein-Leventhal syndrome and idiopathic hirsutism. The diagnostic implications of these results are discussed.

Virilizing adrenocortical carcinoma with Cushing’s syndrome in a 14 months old child

1984 ◽  
Vol 51 (4) ◽  
pp. 497-500 ◽  
Author(s):  
S. Garg ◽  
R. K. Marwaha ◽  
I. C. Pathak ◽  
R. J. Dash
Keyword(s):  
Cushing’S Syndrome ◽  
Adrenocortical Carcinoma ◽  
Cushing's Syndrome

scholarly journals Adrenocortical Carcinoma in a 3 yrs Girl—A Case Report

1970 ◽  
Vol 22 (1) ◽  
pp. 142-143
Author(s):  
M Nowshad Ali ◽  
S Hoq Miah ◽  
M Meharunnesa ◽  
SM Badruddoza ◽  
Mushtaque Ahmed
Keyword(s):  
Case Report ◽  
Precocious Puberty ◽  
Cushing’S Syndrome ◽  
Adrenocortical Carcinoma ◽  
Pediatric Population ◽  
Signs And Symptoms ◽  
Cushing's Syndrome ◽  
Adrenal Tumour ◽  
Uncommon Tumour

Adrenocortical carcinoma is an uncommon tumour in the pediatric population. Account for only a small fraction of pediatric adrenal tumour. Most tumors in children are functional, and virilization is by far the most common presenting symptom, followed by Cushing's syndrome and precocious puberty. All patients with suspected adrenocortical carcinoma should be carefully evaluated for signs and symptoms of hormonal syndromes. DOI: 10.3329/taj.v22i1.5039 TAJ 2009; 22(1): 142-143

scholarly journals Functioning Adrenocortical Carcinoma with Extension upto the Right Atrium Producing Cushing's Syndrome

2013 ◽  
Vol 3 ◽  
pp. 32 ◽  
Author(s):  
Santosh Kumar ◽  
Gautam R. Choudhary ◽  
Arawat Pushkarna
Keyword(s):  
Inferior Vena Cava ◽  
Cushing’S Syndrome ◽  
Adrenocortical Carcinoma ◽  
Right Atrium ◽  
Inferior Vena ◽  
Vena Cava ◽  
Cushing's Syndrome ◽  
Curative Therapy ◽  
Rare Malignancy ◽  
The Right

Adrenocortical carcinoma (ACC) is a rare malignancy with poor prognosis. Surgery is the only curative therapy available and overall 5-year survival for patients who undergo a complete resection is 32% to 48%. They are known to produce intravascular invasion and into the inferior vena cava (IVC) and in rare cases they may reach the right atrium. We report a case of functioning ACC extending into the inferior vena cava and right atrium in a female with Cushing's syndrome.

RE: A CASE OF CUSHING'S SYNDROME DUE TO ADRENOCORTICAL CARCINOMA WITH RECURRENCE 19 MONTHS AFTER LAPAROSCOPIC ADRENALECTOMY

1998 ◽  
Vol 159 (4) ◽  
pp. 1310-1310 ◽  
Author(s):  
T. Ushiyama ◽  
K. Suzuki ◽  
S. Kageyama ◽  
K. Fujita ◽  
Y. Oki ◽  
...  
Keyword(s):  
Cushing’S Syndrome ◽  
Adrenocortical Carcinoma ◽  
Laparoscopic Adrenalectomy ◽  
Cushing's Syndrome

scholarly journals An Adrenocortical Carcinoma Associated with Non-Islet Cell Tumor Hypoglycemia and Aberrant ACTH Production

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
M. D. S. A. Dilrukshi ◽  
A. W. Wickramarachchi ◽  
D. D. K. Abeyaratne ◽  
Brian Shine ◽  
Bahram Jafar-Mohammadi ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Cushing’S Syndrome ◽  
Adrenocortical Carcinoma ◽  
Islet Cell ◽  
Islet Cell Tumor ◽  
Severe Hypoglycemia ◽  
Cushing's Syndrome ◽  
Cell Tumor ◽  
Adrenocortical Carcinomas ◽  
Tumor Hypoglycemia

Introduction. Adrenocortical carcinomas (ACCs) are infrequently reported to present with severe hypoglycemia syndrome resulting from the secretion of insulin-like growth factor II (IGF-II) by tumor cells. Adrenocorticotropic hormone- (ACTH) independent hypercortisolism is the norm of hormonally active ACCs, but aberrant ACTH production by tumor cells can theoretically cause ACTH-dependent hypercortisolism. The purpose of this report was to present a case of an ACC manifested with the co-occurrence of two extremely rare presentations. Case Description. We present a rare case of a 43-year-old male patient admitted with recurrent episodes of severe non-ketotic and non-insulin-mediated hypoglycemia due to IGF-II mediated disease and ACTH-dependent Cushing’s syndrome. He was diagnosed with a diffusely disseminated adrenocortical carcinoma with immunohistochemistry of tumor cells showing focal ACTH immunostain positivity. Conclusion. Non-islet cell tumor hypoglycemia and ACTH-dependent Cushing’s syndrome are extremely rare presentations of an ACC, and co-occurrence of these entities in a single patient is never reported in the literature.

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