Role of Selective Venous Sampling for PTH before Revision Surgery for Persistent Hyperparathyroidism Revisited.

2010 ◽  
pp. P2-244-P2-244
Author(s):  
J.E. Witteveen ◽  
J. Kievit ◽  
J. Morreau ◽  
J.A. Romijn ◽  
N.A.T. Hamdy
Keyword(s):  
Revision Surgery ◽  
Venous Sampling ◽  
Selective Venous Sampling ◽  
Persistent Hyperparathyroidism

scholarly journals The role of selective venous sampling in the management of persistent hyperparathyroidism revisited

2010 ◽  
Vol 163 (6) ◽  
pp. 945-952 ◽  
Author(s):  
Janneke E Witteveen ◽  
Job Kievit ◽  
Arian R van Erkel ◽  
Hans Morreau ◽  
Johannes A Romijn ◽  
...  
Keyword(s):  
Revision Surgery ◽  
Single Photon ◽  
Photon Emission ◽  
Emission Computed Tomography ◽  
Venous Sampling ◽  
Selective Venous Sampling ◽  
Persistent Hyperparathyroidism ◽  
Recurrent Hyperparathyroidism ◽  
Mibi Spect

IntroductionLocalization studies are mandatory prior to revision surgery in patients with persistent hyperparathyroidism in order to improve surgical outcome and reduce the risk of lengthy explorations. However, in this case, noninvasive localization studies are reported to have a poor sensitivity. The aim of our study is to determine the accuracy of selective venous sampling (SVS) for parathyroid hormone (PTH) in localizing residual hyperactive parathyroid glands in patients with persistent or recurrent hyperparathyroidism.Patients and methodsWe retrospectively evaluated the localizing accuracy of 20 PTH SVS performed prior to revision surgery in 18 patients with persistent or recurrent primary hyperparathyroidism (n=11) or autonomous (tertiary) hyperparathyroidism (n=7). Tc99m-methoxy-isobutyle-isonitrile (MIBI)-single photon emission computed tomography (SPECT) was also performed in all patients prior to revision surgery. Operative and pathological data were obtained from hospital records.ResultsThe SVS was able to accurately localize 15 of the 20 pathological glands removed at revision surgery, representing a sensitivity of 75%. This sensitivity is significantly higher than that of Tc99m-MIBI-SPECT, which was only 30% (P=0.012).ConclusionOur findings demonstrate that SVS is a valuable localization study in patients with persistent or recurrent hyperparathyroidism, with a sensitivity significantly higher than that of Tc99m-MIBI-SPECT. Our data suggest that SVS represents a useful addition to the preoperative workup of these patients prior to revision surgery.

Accuracy of selective venous sampling for intact parathyroid hormone in difficult patients with recurrent or persistent hyperparathyroidism

Surgery ◽  
2002 ◽  
Vol 132 (6) ◽  
pp. 944-951 ◽  
Author(s):  
Julia J. Jones ◽  
Laurent Brunaud ◽  
Christopher F. Dowd ◽  
Quan-Yang Duh ◽  
Eugene Morita ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Intact Parathyroid Hormone ◽  
Venous Sampling ◽  
Difficult Patients ◽  
Selective Venous Sampling ◽  
Persistent Hyperparathyroidism

Non–super-selective Venous Sampling for Persistent Hyperparathyroidism Using a Systemic Hypocalcemic Challenge

2012 ◽  
Vol 23 (9) ◽  
pp. 1191-1199 ◽  
Author(s):  
Lilah F. Morris ◽  
Christopher Loh ◽  
Kevin Ro ◽  
James E. Wiseman ◽  
Antoinette S. Gomes ◽  
...  
Keyword(s):  
Venous Sampling ◽  
Selective Venous Sampling ◽  
Persistent Hyperparathyroidism

scholarly journals Selective parathyroid venous sampling in patients with complicated hyperparathyroidism

2006 ◽  
Vol 155 (6) ◽  
pp. 813-821 ◽  
Author(s):  
C M Ogilvie ◽  
P L Brown ◽  
M Matson ◽  
J Dacie ◽  
R H Reznek ◽  
...  
Keyword(s):  
Resonance Imaging ◽  
Venous Sampling ◽  
Valuable Adjunct ◽  
Parathyroid Disease ◽  
Sestamibi Scanning ◽  
Persistent Hyperparathyroidism ◽  
Failed Surgery ◽  
Magnetic Resonance Imaging Mri ◽  
Preoperative Localisation

Objective: The role of preoperative localisation of abnormal parathyroid glands remains controversial but is particularly relevant to the management of patients with recurrent or persistent hyperparathyroidism and familial syndromes. We report our experience of the use of selective parathyroid venous sampling (PVS) in the localisation of parathyroid disease in such patients. Design: We report a retrospective 10-year experience (n = 27) of the use of PVS in complicated primary hyperparathyroidism and contrast the use of PVS with neck ultrasound, magnetic resonance imaging (MRI), computed tomography (CT) and sestamibi imaging modalities. Results: In 14 out of 25 patients who underwent surgery PVS results were completely concordant with surgical and histological findings and 88% of patients achieved post-operative cure. Out of 13 patients referred after previous failed surgery, 12 underwent further surgery which was curative in 9. In total PVS yielded useful positive (n = 13) and/or negative information (n = 6) in 19 out of 25 patients undergoing surgery. Using histology as the gold standard, 59% of PVS studies were entirely consistent with histology, as compared with 39% of ultrasound scans, 36% of sestamibi scans and 17% of MRI/CT scans. Conclusions: PVS is a valuable adjunct to MRI/CT and sestamibi scanning in selected patients with complicated hyperparathyroidism when performed in an experienced unit.

scholarly journals The role of selective venous sampling in patients with non-localized primary hyperparathyroidism

2020 ◽  
Vol 36 (2) ◽  
pp. 164-171
Author(s):  
İlhan Gök ◽  
Nuri Alper Şahbaz ◽  
Cevher Akarsu ◽  
Ahmet Cem Dural ◽  
Meral Mert ◽  
...  
Keyword(s):  
Primary Hyperparathyroidism ◽  
Venous Sampling ◽  
Selective Venous Sampling

Selective Venous Sampling in Recurrent and Persistent Hyperparathyroidism: Indication, Technique, and Results

2004 ◽  
Vol 28 (10) ◽  
pp. 958-961 ◽  
Author(s):  
Philippe C.J. Chaffanjon ◽  
David Voirin ◽  
Ashok Vasdev ◽  
Olivier Chabre ◽  
Norman M. Kenyon ◽  
...  
Keyword(s):  
Venous Sampling ◽  
Selective Venous Sampling ◽  
Persistent Hyperparathyroidism

The Role of Vertebral Body Tethering in Treating Skeletally Immature Scoliosis

2021 ◽  
pp. 155633162110088
Author(s):  
Blake C. Meza ◽  
Andre M. Samuel ◽  
Todd J. Albert
Keyword(s):  
Vertebral Body ◽  
Revision Surgery ◽  
Critical Analysis ◽  
Posterior Spinal Fusion ◽  
Future Research ◽  
Skeletally Immature ◽  
Postoperative Results ◽  
Radiographic Outcomes ◽  
Novel Technology

This is a critical analysis of a study by Hoernschemeyer et al, “Anterior Vertebral Body Tethering for Adolescent Scoliosis with Growth Remaining: A Retrospective Review of 2 to 5-Year Postoperative Results” ( J Bone Joint Surg Am, 2020;102[13]:1169–1176), that assessed the clinical and radiographic outcomes of vertebral body tethering (VBT) in the treatment of adolescent scoliosis. The authors demonstrated successful treatment in 74% of patients, based on radiographic outcomes and avoidance of subsequent posterior spinal fusion. Nearly a quarter of patients required revision surgery. Almost half suffered a broken tether, although the effects of such complications are not fully understood. The study provided valuable information for determining which patients are reasonable candidates for VBT and emphasizes several questions surrounding this novel technology that remain unanswered. This analysis discusses the study’s strengths and weaknesses, suggests potential directions of future research, and examines the potential indications for VBT.

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