Thyrotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus is dependent upon feedback regulation by both triiodothyronine and thyroxine.

Endocrinology ◽  
1992 ◽  
Vol 130 (5) ◽  
pp. 2845-2850 ◽  
Author(s):  
I Kakucska ◽  
W Rand ◽  
R M Lechan
Keyword(s):  
Gene Expression ◽  
Paraventricular Nucleus ◽  
Feedback Regulation ◽  
Thyrotropin Releasing Hormone ◽  
Hypothalamic Paraventricular Nucleus ◽  
Releasing Hormone

scholarly journals Decreased thyrotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus of patients with major depression

2003 ◽  
Vol 8 (10) ◽  
pp. 838-839 ◽  
Author(s):  
A Alkemade ◽  
U A Unmehopa ◽  
J P Brouwer ◽  
W J G Hoogendijk ◽  
W M Wiersinga ◽  
...  
Keyword(s):  
Gene Expression ◽  
Major Depression ◽  
Paraventricular Nucleus ◽  
Thyrotropin Releasing Hormone ◽  
Hypothalamic Paraventricular Nucleus ◽  
Releasing Hormone

Triiodothyronine Exerts Direct Cell-Specific Regulation of Thyrotropin-Releasing Hormone Gene Expression in the Hypothalamic Paraventricular Nucleus*

Endocrinology ◽  
1988 ◽  
Vol 123 (5) ◽  
pp. 2291-2297 ◽  
Author(s):  
ERIC M. DYESS ◽  
THOMAS P. SEGERSON ◽  
ZSOLT LIPOSITS ◽  
WILLIS K. PAULL ◽  
MICHAEL M. KAPLAN ◽  
...  
Keyword(s):  
Gene Expression ◽  
Paraventricular Nucleus ◽  
Thyrotropin Releasing Hormone ◽  
Hypothalamic Paraventricular Nucleus ◽  
Releasing Hormone ◽  
Direct Cell ◽  
Specific Regulation

Effect of different types of stressors on peptide messenger ribonucleic acids in the hypothalamic paraventricular nucleus

1993 ◽  
Vol 128 (6) ◽  
pp. 485-492 ◽  
Author(s):  
Sandra Ceccatelli ◽  
Catello Orazzo
Keyword(s):  
Paraventricular Nucleus ◽  
Immobilization Stress ◽  
Thyrotropin Releasing Hormone ◽  
Hypothalamic Paraventricular Nucleus ◽  
Male Rats ◽  
Mrna Levels ◽  
Corticotropin Releasing Hormone ◽  
Ribonucleic Acids ◽  
Releasing Hormone ◽  
Different Types

Using in situ hybridization we have studied the effects of different types of stressors, such as ether, immobilization, cold and swimming, on the expression of several peptide messenger ribonucleic acids (mRNAs) in the hypothalamic paraventricular nucleus of adult male rats. Paraventricular nucleus sections were hybridized using synthetic oligonucleotide probes complementary to mRNA for corticotropin-releasing hormone, neurotensin, enkephalin and thyrotropin-releasing hormone. A clear upregulation of neurotensin mRNA was seen after ether and, to a lesser extent, after immobilization stress, whereas after the two other stressors neurotensin mRNA was undetectable, as in control rats. An increase in enkephalin mRNA was observed in a selective region of the dorsal part of the medioparvocellular subdivision of the paraventricular nucleus only after ether and immobilization stress. No significant changes were seen in corticotropin-releasing hormone and thyrotropin-releasing hormone mRNA levels in any of the experimental paradigms. The present results show selective changes for various peptide mRNAs in the paraventricular nucleus after various types of stress. Significant effects could be demonstrated only on neurotensin and enkephalin mRNA after ether and immobilization stress. This suggests that adaptive changes in the rate of synthesis, processing and transport of the peptide may develop over a longer period of time.

scholarly journals Thyrotropin-Releasing-Hormone-Synthesizing Neurons of the Hypothalamic Paraventricular Nucleus Are Inhibited by Glycinergic Inputs

Thyroid ◽  
2019 ◽  
Vol 29 (12) ◽  
pp. 1858-1868
Author(s):  
Edina Varga ◽  
Erzsébet Farkas ◽  
Györgyi Zséli ◽  
Andrea Kádár ◽  
Alexandra Venczel ◽  
...  
Keyword(s):  
Paraventricular Nucleus ◽  
Thyrotropin Releasing Hormone ◽  
Hypothalamic Paraventricular Nucleus ◽  
Releasing Hormone
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