Disturbance of Pituitary-Adrenal Interrelationships in Benign Intracranial Hypertension (Pseudotumor Cerebri)

1966 ◽  
Vol 26 (12) ◽  
pp. 1366-1369 ◽  
Author(s):  
MICHAEL B. A. OLDSTONE
Keyword(s):  
Intracranial Hypertension ◽  
Pseudotumor Cerebri ◽  
Benign Intracranial Hypertension

Unilateral papilledema in 'benign' intracranial hypertension (pseudotumor cerebri)

JAMA ◽  
1983 ◽  
Vol 250 (17) ◽  
pp. 2346-2347 ◽  
Author(s):  
N. A. Sher
Keyword(s):  
Intracranial Hypertension ◽  
Pseudotumor Cerebri ◽  
Benign Intracranial Hypertension

Benign Intracranial Hypertension (Pseudotumor Cerebri)

1967 ◽  
Vol 14 (4) ◽  
pp. 819-830 ◽  
Author(s):  
Melvin Greer
Keyword(s):  
Intracranial Hypertension ◽  
Pseudotumor Cerebri ◽  
Benign Intracranial Hypertension

OCCURRENCE OF PSEUDOTUMOR CEREBRI (BENIGN INTRACRANIAL HYPERTENSION) DURING TREATMENT OF CHILDREN WITH ASTHMA BY ADRENAL STEROIDS

PEDIATRICS ◽  
1959 ◽  
Vol 23 (6) ◽  
pp. 1143-1151
Author(s):  
Susan C. Dees ◽  
Hamilton W. Mckay
Keyword(s):  
Intracranial Hypertension ◽  
Steroid Therapy ◽  
Pseudotumor Cerebri ◽  
Steroid Treatment ◽  
Benign Intracranial Hypertension ◽  
Adrenal Steroids ◽  
Sequence Of Events ◽  
Withdrawal Of Treatment ◽  
Small Doses ◽  
Children With Asthma

The development of pseudotumor cerebri (benign intracranial hypertension) is described in three young boys with asthma, who were receiving small doses of adrenal steroids during a stage of withdrawal of treatment. These patients had received continuous steroid treatment for several years, beginning in late infancy. They had acquired the appearance of Cushing's disease. The mechanism by which pseudotumor cerebri developed in these three children was not determined. Various hypotheses are discussed. Attention is called to the sequence of events in these children with asthma as another possible complication of prolonged use of steroid therapy.

BENIGN INTRACRANIAL HYPERTENSION (PSEUDOTUMOR CEREBRI): Review and Report of 18 Cases

1970 ◽  
Vol 59 (3) ◽  
pp. 328-339 ◽  
Author(s):  
B. HAGBERG ◽  
M. SILLANPÄÄ
Keyword(s):  
Intracranial Hypertension ◽  
Pseudotumor Cerebri ◽  
Benign Intracranial Hypertension

scholarly journals Benign Intracranial Hypertension: A Diagnostic Dilemma

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Gary Y. Shaw ◽  
Stephanie K. Million
Keyword(s):  
Intracranial Hypertension ◽  
Signs And Symptoms ◽  
Pseudotumor Cerebri ◽  
Empty Sella ◽  
Definitive Diagnosis ◽  
Benign Intracranial Hypertension ◽  
Imaging Studies ◽  
Diagnostic Challenge ◽  
Diagnostic Dilemma ◽  
Empty Sella Syndrome

Benign intracranial hypertension (BIH) (also known as pseudotumor cerebri and empty sella syndrome) remains a diagnostic challenge to most physicians. The modified Dandy criteria consist of, the classic findings of headache, pulsatile tinnitus, papilledema, and elevated cerebrospinal fluid (CSF) pressure, however, these are rarely collectively present in any one patient. Furthermore, these findings can wax and wane over time. Due to the nature of this disease, both signs and symptoms may be intermittent, making definitive diagnosis difficult. Newer imaging studies, particularly the magnetic resonance venogram (MRV) along with a constellation of correlative findings and associated diseases have given new impetus in the diagnosis, treatment, and pathophysiology of this disease. This has led the authors to offer modifications to the classic Dandy criteria. This report presents three representative cases of BIH highlighting many of the newer advances in both diagnosis and treatment of this perplexing disorder.

scholarly journals Pseudotumor cerebri during Cushing's disease treatment with ketoconazole

2011 ◽  
Vol 55 (4) ◽  
pp. 284-287 ◽  
Author(s):  
Fabiola Costenaro ◽  
Ticiana C. Rodrigues ◽  
Nelson P. Ferreira ◽  
Tiago G. da Costa ◽  
Tiago Schuch ◽  
...  
Keyword(s):  
Visual Field ◽  
Intracranial Hypertension ◽  
Cushing’S Disease ◽  
Magnetic Resonance Image ◽  
Black Spot ◽  
Pseudotumor Cerebri ◽  
Cushing's Disease ◽  
Benign Intracranial Hypertension ◽  
Elevated Intracranial Pressure ◽  
Disease Treatment

Benign intracranial hypertension (Pseudotumor cerebri) has been described as related to the reduction in steroid levels in Cushing's disease (CD), especially after surgical remission. Ketoconazole is a common and effective adjuvant therapy for hypercortisolism, but the major concern is liver enzyme dysfunction. We describe here the case of a 12-year old girl with CD who developed benign intracranial hypertension during treatment with ketoconazole. She presented headache, vomiting, a black spot on her right temporal visual field, and signs of elevated intracranial pressure. Pituitary image was normal on magnetic resonance image (MRI), and all symptoms improved after treatment with acetazolamide. We call attention to the diagnosis of this disorder in CD patients, especially children on ketoconazole treatment, because it could be confounded with adrenal insufficiency and lead to definitive severe visual impairment.

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